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helix-turn-helix domain-containing protein
This helix-turn-helix domain is often found in transposases and is likely to be DNA-binding. (from Pfam)
CENP-B N-terminal DNA-binding domain
Centromere Protein B (CENP-B) is a DNA-binding protein localised to the centromere. Within the N-terminal 125 residues, there is a DNA-binding region, which binds to a corresponding 17bp CENP-B box sequence. CENP-B dimers either bind two separate DNA molecules or alternatively, they may bind two CENP-B boxes on one DNA molecule, with the intervening stretch of DNA forming a loop structure. The CENP-B DNA-binding domain consists of two repeating domains, RP1 and RP2. This family corresponds to RP1 has been shown to consist of four helices in a helix-turn-helix structure [1]. [1]. 9451007. A helix-turn-helix structure unit in human centromere protein B. (CENP-B).. Iwahara J, Kigawa T, Kitagawa K, Masumoto H, Okazaki T, Yokoyama. S;. EMBO J 1998;17:827-837. (from Pfam)
IS630 transposase-related protein
Transposase proteins are necessary for efficient DNA transposition. This family includes insertion sequences from Synechocystis PCC 6803 three of which are characterised as homologous to bacterial IS5- and IS4- and to several members of the IS630-Tc1-mariner superfamily [1]. [1]. 9305771. Three insertion sequences from the cyanobacterium Synechocystis. PCC6803 support the occurrence of horizontal DNA transfer among. bacteria.. Cassier-Chauvat C, Poncelet M, Chauvat F;. Gene 1997;195:257-266. (from Pfam)
transposase
Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family. [1]. 9180700. Genetic organization and transposition properties of IS511.. D. A. Mullin, D. L. Zies, A. H. Mullin, N. Caballera & B. Ely;. Mol Gen Genet 1997;254:456-463.. [2]. 8973350. The use of an improved transposon mutagenesis system for DNA. sequencing leads to the characterization of a new insertion. sequence of Streptomyces lividans 66.. J. Fischer, H. Maier, P. Viell & J. Altenbuchner;. Gene 1996;180:81-89.. [3]. 8917074. Identification and nucleotide sequence of Rhizobium meliloti. insertion sequence ISRm6, a small transposable element that. belongs to the IS3 family.. S. Zekri & N. Toro;. Gene 1996;175:43-48. (from Pfam)
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