Protein Family Models

This is a putative DNA-binding protein dimerization domain found bacterial proteins such as CD3330, (a transposon-related DNA-binding protein from Clostridium difficile). Crystal structure analysis suggests that CD3330 N-terminus is involved in dimer formation and also in crystal packing but the C-terminus is open to solvent [1]. [1]. 20213425. Cleavable C-terminal His-tag vectors for structure. determination.. Eschenfeldt WH, Maltseva N, Stols L, Donnelly MI, Gu M, Nocek B,. Tan K, Kim Y, Joachimiak A;. J Struct Funct Genomics. 2010;11:31-39. (from Pfam)

Date:

2024-04-03

This domain is a helix-turn-helix domain that probably binds to DNA. (from Pfam)

Date:

2023-12-12

Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains. (from Pfam)

Date:

2023-12-12

This large family of DNA binding helix-turn helix proteins includes Cro Swiss:P03036 and CI Swiss:P03034. Within the protein Swiss:Q5F9C2, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family [1]. [1]. 20196080. The crystal structure of NGO0477 from Neisseria gonorrhoeae. reveals a novel protein fold incorporating a helix-turn-helix. motif.. Ren J, Sainsbury S, Nettleship JE, Saunders NJ, Owens RJ;. Proteins. 2010;78:1798-1802. (from Pfam)

Date:

2024-04-03