Protein Family Models

Flagellins polymerise to form bacterial flagella. There is some similarity between this family and Pfam:PF00669, particularly the motif NRFXSXIXXL. It has been suggested that these two regions associate [2] and this is shown to be correct as structurally this family forms an extended helix that interacts with Pfam:PF00700. [1]. 7648320. Spinning tails.. DeRosier DJ;. Curr Opin Struct Biol 1995;5:187-193.. [2]. 2190210. Flagellin as an object for supramolecular engineering.. Fedorov OV, Efimov AV;. Protein Eng 1990;3:411-413. (from Pfam)

Date:

2024-08-14

Flagellins polymerise to form bacterial flagella. This family includes flagellins and hook associated protein 3. Structurally this family forms an extended helix that interacts with Pfam:PF00700. [1]. 7648320. Spinning tails.. DeRosier DJ;. Curr Opin Struct Biol 1995;5:187-193. (from Pfam)

Date:

2024-08-14

lateral flagellin LafA in a rare type of flagellin, which is the subunit protein that polymerizes to form the flagella

Date:

2024-01-12

This HMM describes rare second type of flagellin from E. coli and some closely related species, called LafA, where the familiar and common flagellin, FliC, is nearly universal and carries the H-antigen used for serotyping strains. In contrast to FliC, whose center region is highly variable, LafA shows little variability in sequence. In many E. coli strains, the Flag-2 locus either is absent or is cryptic, appearing degraded and non-functional.

Gene:

lafA

Date:

2020-10-26