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DciA family protein
This family contains several actinomycete proteins. Family members such as DciA (dna[CI] antecedent) found in Pseudomonas aeruginosa, has been shown to share a common function with DnaC (in Escherichia coli) and DnaI (in Bacillus subtilis), acting as a replicative helicase. Furthermore, functional analysis revealed that DciA is essential for replication initiation and protein depletion resulted in a blockage of the initiation of replication after the formation of the open complex [1]. [1]. 27830752. DciA is an ancestral replicative helicase operator essential for. bacterial replication initiation.. Brezellec P, Vallet-Gely I, Possoz C, Quevillon-Cheruel S, Ferat. JL;. Nat Commun. 2016;7:13271. (from Pfam)
DUF721 domain-containing protein
uncharacterized DUF721 domain-containing protein
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