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helix-turn-helix domain-containing protein
This domain represents a DNA-binding Helix-turn-helix domain found in transcriptional regulatory proteins. (from Pfam)
ArsR/SmtB family transcription factor
ArsR (Arsenical Resistance Operon Repressor)/SmtB family transcription factor is a winged-helix-turn-helix transcriptional regulator that may be metal-sensing and modulate the expression of genes associated with metal homeostasis
metalloregulator ArsR/SmtB family transcription factor
Transcriptional repressors that sense toxic heavy metals such as arsenic or cadmium, and are released from DNA so that resistance factors will be expressed, include ArsR, SmtB, ZiaR, CadC, CadX, KmtR, etc. However, some members of this family, including the sporulation delaying system autorepressor SdpR and its family (see NF033789), may lack metal-binding cites and instead regulate other cellular processes.
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