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type II toxin-antitoxin system RelE/ParE family toxin
ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralised by the antitoxin ParD. The family also encompasses RelE/ParE described in [2]. [1]. 1459960. Definition of a minimal plasmid stabilization system from the. broad-host-range plasmid RK2.. Roberts RC, Helinski DR;. J Bacteriol 1992;174:8119-8132.. [2]. 14659018. New connections in the prokaryotic toxin-antitoxin network:. relationship with the eukaryotic nonsense-mediated RNA decay. system.. Anantharaman V, Aravind L;. Genome Biol 2003;4:R81.. [3]. 20487277. Interaction specificity, toxicity and regulation of a paralogous. set of ParE/RelE-family toxin-antitoxin systems.. Fiebig A, Castro Rojas CM, Siegal-Gaskins D, Crosson S;. Mol Microbiol. 2010;77:236-251. (from Pfam)
type II toxin-antitoxin (TA) system RelE/ParE family toxin is the RelE/ParE-like toxin component of a type II toxin-antitoxin system, its activity is attenuated by interaction with its cognate antitoxin
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