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proton-translocating transhydrogenase family protein
PNTB_4TM is the region upstream of family PNTB, Pfam:PF02233, that carries four of this transporters transmembrane regions. PNTB is the beta-subunit of pyridine nucleotide transhydrogenase. This family forms part of the Proton-translocating Transhydrogenase (PTH) Family. (from Pfam)
Alanine dehydrogenase/PNT, N-terminal domain
This family now also contains the lysine 2-oxoglutarate reductases. [1]. 11354603. Lysine metabolism in higher plants.. Azevedo RA, Lea PJ;. Amino Acids 2001;20:261-279. (from Pfam)
Alanine dehydrogenase/PNT, C-terminal domain
NAD(P) transhydrogenase subunit alpha
alpha subunit of NAD(P) transhydrogenase catalyzes the transhydrogenation between NADH and NADP which is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Re/Si-specific NAD(P)(+) transhydrogenase subunit alpha
This integral membrane protein is the alpha subunit of alpha 2 beta 2 tetramer that couples the proton transport across the membrane to the reversible transfer of hydride ion equivalents between NAD and NADP. An alternate name is pyridine nucleotide transhydrogenase alpha subunit. The N-terminal region is homologous to alanine dehydrogenase. In some species, such as Rhodospirillum rubrum, the alpha chain is replaced by two shorter chains, both with some homology to the full-length alpha chain modeled here. These score below the trusted cutoff.
Involved in catalyzing the transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm
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