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TonB-dependent receptor plug domain-containing protein
The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors ([1]). It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel. [1]. 15111112. The plug domain of a neisserial TonB-dependent transporter. retains structural integrity in the absence of its transmembrane. beta-barrel.. Oke M, Sarra R, Ghirlando R, Farnaud S, Gorringe AR, Evans RW,. Buchanan SK;. FEBS Lett 2004;564:294-300. (from Pfam)
TonB-dependent receptor
TonB dependent receptor having a carboxypeptidase regulatory-like domain, may act as a channel to allow import of extracellular nutrients, such as iron-siderophore complexes or non-Fe compounds
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