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aconitase family protein
Members of this family include aconitase (aconitate hydratase), 3-isopropylmalate dehydratase, and homoaconitase.
aconitase/3-isopropylmalate dehydratase large subunit family protein
3-isopropylmalate dehydratase large subunit
3-isopropylmalate dehydratase large subunit catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
3-isopropylmalate dehydratase/homoaconitate hydratase family large subunit
This subfamily is a subset of the larger HacA family (homoaconitate hydratase family, TIGR01343). Many members of this subfamily are archaeal examples of the 3-isopropylmalate dehydratase large subunit, but the family includes additional paralogs that may differ in function as well as proteins characterized as multifunctional.
homoaconitate hydratase family protein
This HMM represents a subfamily of proteins consisting of aconitase, homoaconitase, 3-isopropylmalate dehydratase, and uncharacterized proteins. The majority of the members of this family have been designated as 3-isopropylmalate dehydratase large subunit (LeuC) in microbial genome annotation, but the only characterized member is Thermus thermophilus homoaconitase, an enzyme of a non-aspartate pathway of Lys biosynthesis.
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