Protein Family Models for Protein (Select 1180916812) - Protein Family Models

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Links from Protein

Items: 6

Select item 4138431.

Wzz/FepE/Etk N-terminal domain-containing protein

This HMM describes an N-terminal region of homology share by two different classes of chain length determinant proteins (also known as polysaccharide co-polymerases) and by membrane-bound tyrosine kinases such Etk, involved in the polysaccharide export.

GO Terms:

Biological Process:: lipopolysaccharide biosynthetic process (GO:0009103)

Cellular Component:: membrane (GO:0016020)

Date:: 2024-08-14

Family Accession:: NF014732.5
Method:: HMM

Select item 4132412.

CobQ/CobB/MinD/ParA nucleotide binding domain

This family consists of various cobyrinic acid a,c-diamide synthases. These include CbiA Swiss:P29946 and CbiP Swiss:Q05597 from S.typhimurium [4], and CobQ Swiss:Q52686 from R. capsulatus [3]. These amidases catalyse amidations to various side chains of hydrogenobyrinic acid or cobyrinic acid a,c-diamide in the biosynthesis of cobalamin (vitamin B12) from uroporphyrinogen III. Vitamin B12 is an important cofactor and an essential nutrient for many plants and animals and is primarily produced by bacteria [4]. The family also contains dethiobiotin synthetases as well as the plasmid partitioning proteins of the MinD/ParA family [6]. [1]. 9742225. Cobalamin (vitamin B12) biosynthesis: identification and. characterization of a Bacillus megaterium cobI operon.. Raux E, Lanois A, Warren MJ, Rambach A, Thermes C;. Biochem J 1998;335:159-166.. [2]. 9742226. Cobalamin (vitamin B12) biosynthesis: functional. characterization of the Bacillus megaterium cbi genes required. to convert uroporphyrinogen III into cobyrinic acid a,c-diamide.. Raux E, Lanois A, Rambach A, Warren MJ, Thermes C;. Biochem J 1998;335:167-173.. [3]. 7635831. Identification and sequence analysis of genes involved in late. steps in cobalamin (vitamin B12) synthesis in Rhodobacter. capsulatus.. Pollich M, Klug G;. J Bacteriol 1995;177:4481-4487.. [4]. 8501034. Characterization of the cobalamin (vitamin B12) biosynthetic. genes of Salmonella typhimurium.. Roth JR, Lawrence JG, Rubenfield M, Kieffer-Higgins S, Church. GM;. J Bacteriol 1993;175:3303-3316.. [5]. 10966576. The synthetase domains of cobalamin biosynthesis. amidotransferases cobB and cobQ belong to a . TRUNCATED at 1650 bytes (from Pfam)