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aldo/keto reductase
This family includes a number of K+ ion channel beta chain regulatory domains - these are reported to have oxidoreductase activity [2]. [1]. 8234324. Refined 1.8 A structure of human aldose reductase complexed with. the potent inhibitor zopolrestat.. Wilson DK, Tarle I, Petrash JM, Quiocho FA;. Proc Natl Acad Sci U S A 1993;90:9847-9851.. [2]. 10884227. Structure of the cytoplasmic beta subunit-T1 assembly of. voltage-dependent K+ channels.. Gulbis JM, Zhou M, Mann S, MacKinnon R;. Science 2000;289:123-127. (from Pfam)
2,5-didehydrogluconate reductase DkgB
2,5-didehydrogluconate reductase DkgB is an aldo/keto reductase family protein that catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid
Catalyzes the reduction of 2,5-didehydro-D-gluconic acid to 2-dehydro-L-gulonic acid
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