Protein Family Models for Protein (Select 1002972057) - Protein Family Models

Select item 4266991.

stealth conserved region 3 domain-containing protein

Stealth_CR3 is the third of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. The domain is found in tandem with CR1, CR2 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system [1]. [1]. 16299590. Stealth proteins: in silico identification of a novel protein. family rendering bacterial pathogens invisible to host immune. defense.. Sperisen P, Schmid CD, Bucher P, Zilian O;. PLoS Comput Biol. 2005;1:e63. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF028412.5
Method:: HMM

Select item 4265142.

Stealth CR1 domain-containing protein

Stealth_C1 is the first of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. CR1 carries a well-conserved IDVVYT sequence-motif. The domain is found in tandem with CR2, CR3 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system [1]. [1]. 16299590. Stealth proteins: in silico identification of a novel protein. family rendering bacterial pathogens invisible to host immune. defense.. Sperisen P, Schmid CD, Bucher P, Zilian O;. PLoS Comput Biol. 2005;1:e63. (from Pfam)

Date:: 2024-08-14

Family Accession:: NF028411.5
Method:: HMM

Select item 4201463.

Stealth protein CR2, conserved region 2

Stealth_CR2 is the second of several highly conserved regions on stealth proteins in metazoa and bacteria. There are up to four CR regions on all member proteins. CR2 carries a well-conserved NDD sequence-motif. The domain is found in tandem with CR1, CR3 and CR4 on both potential metazoan hosts and pathogenic eubacterial species that are capsular polysaccharide phosphotransferases. The CR domains appear on eukaryotic proteins such as GNPTAB, N-acetylglucosamine-1-phosphotransferase subunits alpha/beta. Horizontal gene-transfer seems to have occurred between host and bacteria of these sequence-regions in order for the bacteria to evade detection by the host innate immune system [1]. [1]. 16299590. Stealth proteins: in silico identification of a novel protein. family rendering bacterial pathogens invisible to host immune. defense.. Sperisen P, Schmid CD, Bucher P, Zilian O;. PLoS Comput Biol. 2005;1:e63. (from Pfam)

GO Terms:

Molecular Function:: transferase activity, transferring phosphorus-containing groups (GO:0016772)

Date:: 2024-08-14

Family Accession:: NF022822.5
Method:: HMM

Select item 4056254.