Protein Family Models

translation initiation factor IF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA

Date:

2019-08-16

This model represents the archaeal translation initiation factor 2 subunit gamma and is found in all known archaea. eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.

Gene:

eif2g

Date:

2019-09-10

eIF-2G; forms a ternary complex with GTP and initiator tRNA in the early steps of protein synthesis

Date:

2020-10-26

Proteins with a small GTP-binding domain recognized by this model include Ras, RhoA, Rab11, translation elongation factor G, translation initiation factor IF-2, tetratcycline resistance protein TetM, CDC42, Era, ADP-ribosylation factors, tdhF, and many others. In some proteins the domain occurs more than once. This model recognizes a large number of small GTP-binding proteins and related domains in larger proteins. Note that the alpha chains of heterotrimeric G proteins are larger proteins in which the NKXD motif is separated from the GxxxxGK[ST] motif (P-loop) by a long insert and are not easily detected by this model.

Date:

2022-03-28