Protein Family Models for Gene (Select 66913262) - Protein Family Models

Select item 3931601.

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Family Accession:

Select item 3901272.

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Family Accession:

Select item 3523413.

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Family Accession:

Select item 3470944.

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Family Accession:

Select item 2272455.

Fpg/Nei family DNA glycosylase

Fpg/Nei family DNA glycosylase similar to Escherichia coli DNA-formamidopyrimidine glycosylase (Fpg), a DNA repair enzyme that excises oxidized purines from damaged DNA

Date:: 2024-08-28

Family Accession:: 11479425
Method:: Sparcle

Select item 1775676.

bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase

Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases

Gene:: mutM

GO Terms:

Molecular Function:: nucleic acid binding (GO:0003676)

Molecular Function:: damaged DNA binding (GO:0003684)

Molecular Function:: DNA-(apurinic or apyrimidinic site) endonuclease activity (GO:0003906)

Biological Process:: DNA repair (GO:0006281)

Biological Process:: base-excision repair (GO:0006284)

Molecular Function:: zinc ion binding (GO:0008270)

Molecular Function:: oxidized purine nucleobase lesion DNA N-glycosylase activity (GO:0008534)

Molecular Function:: hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799)

Molecular Function:: DNA N-glycosylase activity (GO:0019104)

Date:: 2021-07-22

Family Accession:: NF002211.1
Method:: HMM

Select item 223787.

DNA-formamidopyrimidine glycosylase

All proteins in the FPG family with known functions are FAPY-DNA glycosylases that function in base excision repair. Homologous to endonuclease VIII (nei). This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).

Gene:: mutM

GO Terms:

Cellular Component:: cytoplasm (GO:0005737)

Biological Process:: DNA repair (GO:0006281)

Molecular Function:: oxidized purine nucleobase lesion DNA N-glycosylase activity (GO:0008534)

Molecular Function:: metal ion binding (GO:0046872)

Date:: 2024-05-30

Family Accession:: TIGR00577.1
Method:: HMM

Protein Family Models

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