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GTP cyclohydrolase MptA
This HMM has been narrowed in scope, to include the GTP cyclohydrolase MptA involved in methanopterin biosynthesis in archaea (EC 3.5.4.39), but to no longer include FolE2, involved in de novo tetrahydrofolate biosynthesis in some bacteria.
GTP cyclohydrolase IV
GTP cyclohydrolase IV converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin
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