This HMM represents a subfamily of proteins consisting of aconitase, homoaconitase, 3-isopropylmalate dehydratase, and uncharacterized proteins. The majority of the members of this family have been designated as 3-isopropylmalate dehydratase large subunit (LeuC) in microbial genome annotation, but the only characterized member is Thermus thermophilus homoaconitase, an enzyme of a non-aspartate pathway of Lys biosynthesis.
GO Terms:- Biological Process:
- amino acid biosynthetic process (GO:0008652)
- Molecular Function:
- hydro-lyase activity (GO:0016836)
- Molecular Function:
- 4 iron, 4 sulfur cluster binding (GO:0051539)
- Date:
- 2024-05-30