Protein Family Models

TCP-1/cpn60 chaperonin family protein similar to thermosome subunit, a molecular chaperone that binds unfolded polypeptides in vitro, and has a weak ATPase activity

Date:

2020-06-18

Thermosome is the name given to the archaeal rather than eukaryotic form of the group II chaperonin (counterpart to the group I chaperonin, GroEL/GroES, in bacterial), a torroidal, ATP-dependent molecular chaperone that assists in the folding or refolding of nascent or denatured proteins. Various homologous subunits, one to five per archaeal genome, may be designated alpha, beta, etc., but phylogenetic analysis does not show distinct alpha subunit and beta subunit lineages traceable to ancient paralogs.

Date:

2019-09-10