Protein Family Models for Gene (Select 1448126) - Protein Family Models

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Select item 2512213.

succinate-CoA ligase subunit beta

This model is designated subfamily because it does not discriminate the ADP-forming enzyme ((EC 6.2.1.5) from the GDP_forming (EC 6.2.1.4) enzyme. The N-terminal half is described by the CoA-ligases HMM (PF00549). The C-terminal half is described by the ATP-grasp HMM (PF02222). This family contains a split seen both in a maximum parsimony tree (which ignores gaps) and in the gap pattern near position 85 of the seed alignment. Eukaryotic and most bacterial sequences are longer and contain a region similar to TXQTXXXG. Sequences from Deinococcus radiodurans, Mycobacterium tuberculosis, Streptomyces coelicolor, and the Archaea are 6 amino acids shorter in that region and contain a motif resembling [KR]G

Gene:: sucC

GO Terms:

Molecular Function:: succinate-CoA ligase activity (GO:0004774)

Biological Process:: tricarboxylic acid cycle (GO:0006099)

Date:: 2024-06-27

Family Accession:: TIGR01016.1
Method:: HMM

Select item 2363414.

ADP-forming succinate--CoA ligase subunit beta

Gene:: sucC

GO Terms:

Molecular Function:: catalytic activity (GO:0003824)

Molecular Function:: ATP binding (GO:0005524)

Biological Process:: tricarboxylic acid cycle (GO:0006099)

Molecular Function:: metal ion binding (GO:0046872)

Date:: 2021-07-22

Family Accession:: NF001913.0
Method:: HMM

Protein Family Models

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