Protein Family Models

Members of this family occur exclusively in the genus Leptospira, and regularly occur in a locus that includes proteins annotated as D-sedoheptulose 7-phosphate isomerase (an LPS biosynthesis enzyme), glycosyltransferase, O-antigen ligase.

Date:

2024-09-20

Members of this family of chromosomal class D beta-lactamase share about 88% identity with OXA-50 of Pseudomonas aeruginosa, and can be found in the closely related species Pseudomonas paraeruginosa. The family is named OXA-50-var to signify its close relationship with but also its difference from the closely related OXA-50 family.

Gene:

blaOXA

Date:

2024-08-23

This family of class D beta-lactamases is known primarily from Acinetobacter faecalis.

Gene:

blaOXA

Date:

2024-08-17

This strictly chlamydial protein family of about 400 amino acids is named for founding member CT_392 from Chlamydia trachomatis D/UW-3/CX.

Date:

2024-07-25

Gene:

rbsU

Date:

2024-07-18

bifunctional NADH-quinone oxidoreductase subunit C/D (NuoC/NuoD) is part of the connecting domain of complex I of the respiratory chain that couples the transfer of electrons from NADH to quinone with the translocation of protons across the membrane

Date:

2024-04-11

3-deoxy-7-phosphoheptulonate synthase catalyzes the condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) to produce 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP), the first step of the shikimate pathway for aromatic amino acid biosynthesis

Date:

2024-02-09

glycoside hydrolase family 97 protein such as Bacteroides thetaiotaomicron glucan 1,4-alpha-glucosidase SusB and retaining alpha-galactosidase, which hydrolyze terminal, non-reducing (1->4)-linked alpha-D-glucose and alpha-D-galactose, respectively

Date:

2024-02-09

tryptophan synthase catalyzes the conversion of L-serine and 1-C-(indol-3-yl)glycerol 3-phosphate to L-tryptophan and D-glyceraldehyde 3-phosphate

Date:

2024-02-09

1-phosphofructokinase family hexose kinase such as 1-phosphofructokinase, which catalyzes the ATP-dependent conversion of D-fructose 1-phosphate to D-fructose 1,6-bisphosphate and is involved in the utilization of fructose as a sole carbon and energy source

Date:

2024-02-09

1,3-beta-glucan synthase is a glycosyltransferase family 48 protein that catalyzes the addition of glucose to a ((1->3)-beta-D-glucosyl) chain

Date:

2024-02-09

phosphatidylinositol 4-kinase (PI4K) catalyzes the transfer of the gamma-phosphoryl group from ATP to the 4-hydroxyl of the inositol ring of D-myo-phosphatidylinositol (PtdIns) to generate PtdIns(4)P, the major precursor in the synthesis of other phosphoinositides

Date:

2024-02-09

L,D-transpeptidase catalyzes the formation of 3--3 peptidoglycan cross-links

Date:

2024-02-09

1,4-alpha-glucan-branching protein transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain

Date:

2024-02-09

L,D-transpeptidase catalyzes the formation of 3--3 peptidoglycan cross-links

Date:

2024-02-09

PD-(D/E)XK nuclease family protein similar to uncharacterized Fromanvirus gene 69 protein

Date:

2024-02-09

glycosyltransferase family 87 protein such as mycobacterial alpha-(1->3)-arabinofuranosyltransferase, which catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor, beta-D-arabinofuranosyl-1-monophosphoryldecaprenol, on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of arabinogalactan

Date:

2024-02-09

alkaline phosphatase D family protein similar to Bacillus subtilis alkaline phosphatase D (PhoD), which catalyzes the hydrolysis of a phosphate monoester to produce the corresponding alcohol and phosphate

Date:

2024-02-09

L,D-transpeptidase catalyzes the formation of 3--3 peptidoglycan cross-links

Date:

2024-02-09

serine hydrolase domain-containing protein may have hydrolase activity such as Staphylococcus aureus teichoic acid D-alanine hydrolase, transferase activity such as Aspergillus terreus monacolin J acid methylbutanoyltransferase, or may be catalytically inactive

Date:

2024-02-09