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Sds3-like
Repression of gene transcription is mediated by histone deacetylases containing repressor-co-repressor complexes, which are recruited to promoters of target genes via interactions with sequence-specific transcription factors. The co-repressor complex contains a core of at least seven proteins [1]. This family represents the conserved region found in Sds3, Dep1 and BRMS1-homologue p40 proteins. [1]. 15451426. Identification of a novel BRMS1-homologue protein p40 as a. component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex.. Nikolaev AY, Papanikolaou NA, Li M, Qin J, Gu W;. Biochem Biophys Res Commun. 2004;323:1216-1222. (from Pfam)
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