Mean (±SE) change in minimal coronary artery diameter according to intake of different nutrients, with adjustments as in (see footnote 1), except that total fat was not adjusted for carbohydrate, and carbohydrate and protein were also adjusted for polyunsaturated fat. These models estimate the effect of saturated fat replacing other fats (monounsaturated or polyunsaturated), monounsaturated fat replacing other fats (saturated or polyunsaturated), polyunsaturated fat replacing other fats (saturated or monounsaturated), total fat replacing carbohydrate, carbohydrate replacing saturated or monounsaturated fat, and protein replacing saturated or monounsaturated fat. Median intakes (% of energy) for quartiles 1-4 were as follows: saturated fat (6.1, 7.8, 9.5, and 12.0), monounsaturated fat (6.9, 8.6, 10.7, and 13.0), polyunsaturated fat (3.9, 5.2, 6.1, and 7.5), total fat (17.6, 21.7, 27.0, and 31.9), carbohydrate (47.1, 55.6, 60.5, and 68.9), and protein (12.7, 15.8, 18.0, and 21.2). P for trend = 0.001 (saturated fat), 0.40 (monounsaturated fat), 0.04 (polyunsaturated fat), 0.48 (total fat), 0.20 (protein), and 0.001 (carbohydrate).