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Links from Protein

Items: 6

1.
IL-3R-alpha blockade inhibits tumor endothelial cell-derived extracellular vesicle (EV)-mediated vessel formation by targeting the β-catenin pathway
Giusy Lombardo, Maddalena Gili, Cristina Grange, Claudia Cavallari, Patrizia Dentelli, Gabriele Togliatto, Daniela Taverna, Giovanni Camussi, Maria Felice Brizzi
Oncogene. 2018; 37(9): 1175–1191. Published online 2017 Dec 14. doi: 10.1038/s41388-017-0034-x
PMCID:
PMC5861089
AbstractArticlePDF–4.7M
2.
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling
Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero, Winnie L. Kan, Emma F. Barry, Mara Dottore, Karen S. Cheung Tung Shing, Craig J. Morton, Urmi Dhagat, Matthew P. Hardy, Nicholas J. Wilson, Matthew T. Downton, Christine Schieber, Timothy P. Hughes, Angel F. Lopez, Michael W. Parker
Nat Commun. 2018; 9: 386. Published online 2018 Jan 26. doi: 10.1038/s41467-017-02633-7
PMCID:
PMC5785977
AbstractArticlePDF–6.3M
3.
Whole-Genome Sequencing of a Family with Hereditary Pulmonary Alveolar Proteinosis Identifies a Rare Structural Variant Involving CSF2RA/CRLF2/IL3RA Gene Disruption
Chih-Yung Chiu, Shih-Chi Su, Wen-Lang Fan, Shen-Hao Lai, Ming-Han Tsai, Shih-Hsiang Chen, Kin-Sun Wong, Wen-Hung Chung
Sci Rep. 2017; 7: 43469. Published online 2017 Feb 24. doi: 10.1038/srep43469
PMCID:
PMC5324064
AbstractArticlePDF–1.0M
4.
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors.
A Yoshimura, T Ohkubo, T Kiguchi, N A Jenkins, D J Gilbert, N G Copeland, T Hara, A Miyajima
EMBO J. 1995 Jun 15; 14(12): 2816–2826. doi: 10.1002/j.1460-2075.1995.tb07281.x
PMCID:
PMC398400
SummaryPage BrowsePDF–2.6M
5.
Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.
J M Woodcock, B Zacharakis, G Plaetinck, C J Bagley, S Qiyu, T R Hercus, J Tavernier, A F Lopez
EMBO J. 1994 Nov 1; 13(21): 5176–5185. doi: 10.1002/j.1460-2075.1994.tb06848.x
PMCID:
PMC395466
SummaryPage BrowsePDF–1.9M
6.
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors
Con Panousis, Urmi Dhagat, Kirsten M. Edwards, Veronika Rayzman, Matthew P. Hardy, Hal Braley, Gail M. Gauvreau, Timothy R. Hercus, Steven Smith, Roma Sehmi, Laura McMillan, Mara Dottore, Barbara J. McClure, Louis J. Fabri, Gino Vairo, Angel F Lopez, Michael W. Parker, Andrew D. Nash, Nicholas J. Wilson, Michael J. Wilson, Catherine M. Owczarek
MAbs. 2016 Apr; 8(3): 436–453. Published online 2015 Dec 14. doi: 10.1080/19420862.2015.1119352
PMCID:
PMC4966837
AbstractArticlePDF–1.3M

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