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Select item 30395701.

Initial characterization of the human central proteome

Thomas R Burkard, Melanie Planyavsky, Ines Kaupe, Florian P Breitwieser, Tilmann Bürckstümmer, Keiryn L Bennett, Giulio Superti-Furga, Jacques Colinge

BMC Syst Biol. 2011; 5: 17. Published online 2011 Jan 26. doi: 10.1186/1752-0509-5-17

PMCID:: PMC3039570

Abstract Article PDF–2.3M

Select item 27904432.

Novel interactions of CLN5 support molecular networking between Neuronal Ceroid Lipofuscinosis proteins

Annina Lyly, Carina von Schantz, Claudia Heine, Mia-Lisa Schmiedt, Tessa Sipilä, Anu Jalanko, Aija Kyttälä

BMC Cell Biol. 2009; 10: 83. Published online 2009 Nov 26. doi: 10.1186/1471-2121-10-83

PMCID:: PMC2790443

Abstract Article PDF–2.0M

Select item 26350563.

Crystal Structure and Autoactivation Pathway of the Precursor Form of Human Tripeptidyl-peptidase 1, the Enzyme Deficient in Late Infantile Ceroid Lipofuscinosis

Jayita Guhaniyogi, Istvan Sohar, Kalyan Das, Ann M. Stock, Peter Lobel

J Biol Chem. 2009 Feb 6; 284(6): 3985–3997. doi: 10.1074/jbc.M806943200

PMCID:: PMC2635056

Abstract Article PDF–884K

Select item 17350244.

Identification of novel CLN2 mutations shows Canadian specific NCL2 alleles

W Ju, R Zhong, S Moore, D Moroziewicz, J Currie, P Parfrey, W Brown, N Zhong

J Med Genet. 2002 Nov; 39(11): 822–825. doi: 10.1136/jmg.39.11.822

PMCID:: PMC1735024

Summary PDF–99K

Select item 13778955.

Mutational analysis of the defective protease in classic late-infantile neuronal ceroid lipofuscinosis, a neurodegenerative lysosomal storage disorder.

D E Sleat, R M Gin, I Sohar, K Wisniewski, S Sklower-Brooks, R K Pullarkat, D N Palmer, T J Lerner, R M Boustany, P Uldall, A N Siakotos, R J Donnelly, P Lobel

Am J Hum Genet. 1999 Jun; 64(6): 1511–1523. doi: 10.1086/302427

Correction in:: Am J Hum Genet. 2004 Dec; 75(6): 1158.

PMCID:: PMC1377895

Summary PDF–477K

Select item 5289286.

The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)

Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504

Correction in:: Genome Res. 2006 Jun; 16(6): 804.

PMCID:: PMC528928

Abstract Article PDF–140K

Select item 4036977.

The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment

Hilary F. Clark, Austin L. Gurney, Evangeline Abaya, Kevin Baker, Daryl Baldwin, Jennifer Brush, Jian Chen, Bernard Chow, Clarissa Chui, Craig Crowley, Bridget Currell, Bethanne Deuel, Patrick Dowd, Dan Eaton, Jessica Foster, Christopher Grimaldi, Qimin Gu, Philip E. Hass, Sherry Heldens, Arthur Huang, Hok Seon Kim, Laura Klimowski, Yisheng Jin, Stephanie Johnson, James Lee, Lhney Lewis, Dongzhou Liao, Melanie Mark, Edward Robbie, Celina Sanchez, Jill Schoenfeld, Somasekar Seshagiri, Laura Simmons, Jennifer Singh, Victoria Smith, Jeremy Stinson, Alicia Vagts, Richard Vandlen, Colin Watanabe, David Wieand, Kathryn Woods, Ming-Hong Xie, Daniel Yansura, Sothy Yi, Guoying Yu, Jean Yuan, Min Zhang, Zemin Zhang, Audrey Goddard, William I. Wood, Paul Godowski

Genome Res. 2003 Oct; 13(10): 2265–2270. doi: 10.1101/gr.1293003

Correction in:: Genome Res. 2003 Dec; 13(12): 2759.

PMCID:: PMC403697

Abstract Article PDF–120K

Select item 68515598.

Mutation update: Review of TPP1 gene variants associated with neuronal ceroid lipofuscinosis CLN2 disease

Emily Gardner, Mitch Bailey, Angela Schulz, Mikel Aristorena, Nicole Miller, Sara E. Mole

Hum Mutat. 2019 Nov; 40(11): 1924–1938. Published online 2019 Jul 26. doi: 10.1002/humu.23860

PMCID:: PMC6851559

Abstract Article PDF–1.2M

Select item 68222439.

High‐throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification

Yi Zhu, Tobias Weiss, Qiushi Zhang, Rui Sun, Bo Wang, Xiao Yi, Zhicheng Wu, Huanhuan Gao, Xue Cai, Guan Ruan, Tiansheng Zhu, Chao Xu, Sai Lou, Xiaoyan Yu, Ludovic Gillet, Peter Blattmann, Karim Saba, Christian D. Fankhauser, Michael B. Schmid, Dorothea Rutishauser, Jelena Ljubicic, Ailsa Christiansen, Christine Fritz, Niels J. Rupp, Cedric Poyet, Elisabeth Rushing, Michael Weller, Patrick Roth, Eugenia Haralambieva, Silvia Hofer, Chen Chen, Wolfram Jochum, Xiaofei Gao, Xiaodong Teng, Lirong Chen, Qing Zhong, Peter J. Wild, Ruedi Aebersold, Tiannan Guo

Mol Oncol. 2019 Nov; 13(11): 2305–2328. Published online 2019 Sep 18. doi: 10.1002/1878-0261.12570

PMCID:: PMC6822243

Abstract Article PDF–6.5M

Select item 675392110.

Urine proteome changes in rats subcutaneously inoculated with approximately ten tumor cells

Jing Wei, Wenshu Meng, Youhe Gao

PeerJ. 2019; 7: e7717. Published online 2019 Sep 17. doi: 10.7717/peerj.7717

PMCID:: PMC6753921

Abstract Article PDF–5.2M

Select item 674507611.

Endo-lysosomal proteins and ubiquitin CSF concentrations in Alzheimer’s and Parkinson’s disease

Simon Sjödin, Gunnar Brinkmalm, Annika Öhrfelt, Lucilla Parnetti, Silvia Paciotti, Oskar Hansson, John Hardy, Kaj Blennow, Henrik Zetterberg, Ann Brinkmalm

Alzheimers Res Ther. 2019; 11: 82. Published online 2019 Sep 14. doi: 10.1186/s13195-019-0533-9

PMCID:: PMC6745076

Abstract Article PDF–1.4M

Select item 668504912.

Exploring the Mitochondrial Degradome by the TAILS Proteomics Approach in a Cellular Model of Parkinson’s Disease

Marta Lualdi, Maurizio Ronci, Mara Zilocchi, Federica Corno, Emily S. Turilli, Mauro Sponchiado, Antonio Aceto, Tiziana Alberio, Mauro Fasano

Front Aging Neurosci. 2019; 11: 195. Published online 2019 Jul 31. doi: 10.3389/fnagi.2019.00195

PMCID:: PMC6685049

Abstract Article PDF–1.5M

Select item 644529513.

Detection of BDNF-Related Proteins in Human Perilymph in Patients With Hearing Loss

Ines de Vries, Heike Schmitt, Thomas Lenarz, Nils Prenzler, Sameer Alvi, Hinrich Staecker, Martin Durisin, Athanasia Warnecke

Front Neurosci. 2019; 13: 214. Published online 2019 Mar 26. doi: 10.3389/fnins.2019.00214

PMCID:: PMC6445295

Abstract Article PDF–2.4M

Select item 631747614.

Targeted Analysis of Lysosomal Directed Proteins and Their Sites of Mannose-6-phosphate Modification

Tomislav Čaval, Jing Zhu, Weihua Tian, Sanne Remmelzwaal, Zhang Yang, Henrik Clausen, Albert J.R. Heck

Mol Cell Proteomics. 2019 Jan; 18(1): 16–27. Published online 2018 Sep 20. doi: 10.1074/mcp.RA118.000967

PMCID:: PMC6317476

Abstract Article PDF–535K

Select item 627369615.

A SILAC-Based Approach Elicits the Proteomic Responses to Vancomycin-Associated Nephrotoxicity in Human Proximal Tubule Epithelial HK-2 Cells

Zhi-Ling Li, Shu-Feng Zhou

Molecules. 2016 Feb; 21(2): 148. Published online 2016 Jan 29. doi: 10.3390/molecules21020148

PMCID:: PMC6273696

Abstract Article PDF–9.5M

Select item 615647016.

Systems pathology analysis identifies neurodegenerative nature of age‐related vitreoretinal interface diseases

Tiina Öhman, Fitsum Tamene, Helka Göös, Sirpa Loukovaara, Markku Varjosalo

Aging Cell. 2018 Oct; 17(5): e12809. Published online 2018 Jul 2. doi: 10.1111/acel.12809

PMCID:: PMC6156470

Abstract Article PDF–2.7M

Select item 613867217.

Proteomics reveals signal peptide features determining the client specificity in human TRAP-dependent ER protein import

Duy Nguyen, Regine Stutz, Stefan Schorr, Sven Lang, Stefan Pfeffer, Hudson H. Freeze, Friedrich Förster, Volkhard Helms, Johanna Dudek, Richard Zimmermann

Nat Commun. 2018; 9: 3765. Published online 2018 Sep 14. doi: 10.1038/s41467-018-06188-z

PMCID:: PMC6138672

Abstract Article PDF–2.0M

Select item 607403418.

Proteomic distinction of renal oncocytomas and chromophobe renal cell carcinomas

Vanessa Drendel, Bianca Heckelmann, Christoph Schell, Lucas Kook, Martin L. Biniossek, Martin Werner, Cordula A. Jilg, Oliver Schilling

Clin Proteomics. 2018; 15: 25. Published online 2018 Aug 3. doi: 10.1186/s12014-018-9200-6

PMCID:: PMC6074034

Abstract Article PDF–1.7M

Select item 598873019.

Neuromelanin organelles are specialized autolysosomes that accumulate undegraded proteins and lipids in aging human brain and are likely involved in Parkinson’s disease

Fabio A. Zucca, Renzo Vanna, Francesca A. Cupaioli, Chiara Bellei, Antonella De Palma, Dario Di Silvestre, Pierluigi Mauri, Sara Grassi, Alessandro Prinetti, Luigi Casella, David Sulzer, Luigi Zecca

NPJ Parkinsons Dis. 2018; 4: 17. Published online 2018 Jun 5. doi: 10.1038/s41531-018-0050-8

PMCID:: PMC5988730

Abstract Article PDF–2.9M

Select item 593283220.

Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation

Charlotte H. Hulme, Emma L. Wilson, Heidi R. Fuller, Sally Roberts, James B. Richardson, Pete Gallacher, Mandy J. Peffers, Sally L. Shirran, Catherine H. Botting, Karina T. Wright

Arthritis Res Ther. 2018; 20: 87. Published online 2018 May 2. doi: 10.1186/s13075-018-1573-4

PMCID:: PMC5932832

Abstract Article PDF–1.0M

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