PMC Articles for PubChem Compound (Select 46216556) - PMC

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Items: 12

Select item 80796911.

The heat shock response, determined by QuantiGene multiplex, is impaired in HD mouse models and not caused by HSF1 reduction

Casandra Gomez-Paredes, Michael A. Mason, Bridget A. Taxy, Aikaterini S. Papadopoulou, Paolo Paganetti, Gillian P. Bates

Sci Rep. 2021; 11: 9117. Published online 2021 Apr 27. doi: 10.1038/s41598-021-88715-5

PMCID:: PMC8079691

Abstract Article PDF–5.7M

Select item 76639192.

Priming with HDAC Inhibitors Sensitizes Ovarian Cancer Cells to Treatment with Cisplatin and HSP90 Inhibitors

Ana J. Rodrigues Moita, Jan J. Bandolik, Finn K. Hansen, Thomas Kurz, Alexandra Hamacher, Matthias U. Kassack

Int J Mol Sci. 2020 Nov; 21(21): 8300. Published online 2020 Nov 5. doi: 10.3390/ijms21218300

PMCID:: PMC7663919

Abstract Article PDF–3.5M

Select item 73817373.

Hsp90 inhibitor HSP990 in very low dose upregulates EAAT2 and exerts potent antiepileptic activity

Longze Sha, Ting Chen, Yu Deng, Tingfu Du, Kaili Ma, Wanwan Zhu, Yan Shen, Qi Xu

Theranostics. 2020; 10(18): 8415–8429. Published online 2020 Jul 9. doi: 10.7150/thno.44721

PMCID:: PMC7381737

Abstract Article PDF–2.3M

Select item 53526024.

Re-examining HSPC1 inhibitors

Sheah Lin Lee, Nina Claire Dempsey-Hibbert, Dale Vimalachandran, Terence David Wardle, Paul A. Sutton, John H. H. Williams

Cell Stress Chaperones. 2017 Mar; 22(2): 293–306. Published online 2017 Mar 2. doi: 10.1007/s12192-017-0774-0

PMCID:: PMC5352602

Abstract Article PDF–1.2M

Select item 50449795.

Chapter 22: Hsp90 as a potential therapeutic target in retinal disease

Mònica Aguilà, Michael E. Cheetham

Adv Exp Med Biol. Author manuscript; available in PMC 2016 Sep 30.

Published in final edited form as: Adv Exp Med Biol. 2016; 854: 161–167. doi: 10.1007/978-3-319-17121-0_22

PMCID:: PMC5044979

Abstract Article PDF–313K

Select item 44897366.

In Vivo Profiling Reveals a Competent Heat Shock Response in Adult Neurons: Implications for Neurodegenerative Disorders

Alisia Carnemolla, Hayley Lazell, Saliha Moussaoui, Gillian P. Bates

PLoS One. 2015; 10(7): e0131985. Published online 2015 Jul 2. doi: 10.1371/journal.pone.0131985

PMCID:: PMC4489736

Abstract Article PDF–2.2M

Select item 43334977.

A first-in-human phase I, dose-escalation, multicentre study of HSP990 administered orally in adult patients with advanced solid malignancies

A Spreafico, J-P Delord, L De Mattos-Arruda, Y Berge, J Rodon, E Cottura, P L Bedard, M Akimov, H Lu, S Pain, A Kaag, L L Siu, J Cortes

Br J Cancer. 2015 Feb 17; 112(4): 650–659. Published online 2015 Jan 27. doi: 10.1038/bjc.2014.653

PMCID:: PMC4333497

Abstract Article PDF–427K

Select item 40651448.

Contesting the dogma of an age-related heat shock response impairment: implications for cardiac-specific age-related disorders

Alisia Carnemolla, John P. Labbadia, Hayley Lazell, Andreas Neueder, Saliha Moussaoui, Gillian P. Bates

Hum Mol Genet. 2014 Jul 15; 23(14): 3641–3656. Published online 2014 Feb 19. doi: 10.1093/hmg/ddu073

PMCID:: PMC4065144

Abstract Article PDF–2.7M

Select item 39598219.

Hsp90 inhibition protects against inherited retinal degeneration

Mònica Aguilà, Dalila Bevilacqua, Caroline McCulley, Nele Schwarz, Dimitra Athanasiou, Naheed Kanuga, Sergey S. Novoselov, Clemens A.K. Lange, Robin R. Ali, James W. Bainbridge, Carlos Gias, Peter J. Coffey, Pere Garriga, Michael E. Cheetham

Hum Mol Genet. 2014 Apr 15; 23(8): 2164–2175. Published online 2013 Dec 2. doi: 10.1093/hmg/ddt613

PMCID:: PMC3959821

Abstract Article PDF–1.4M

Select item 383487310.

Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells

KATHRIN ZITZMANN, GALINA AILER, GEORGE VLOTIDES, GERALD SPOETTL, JULIAN MAURER, BURKHARD GÖKE, FELIX BEUSCHLEIN, CHRISTOPH J. AUERNHAMMER

Int J Oncol. 2013 Dec; 43(6): 1824–1832. Published online 2013 Oct 4. doi: 10.3892/ijo.2013.2130

PMCID:: PMC3834873

Abstract Article PDF–1.0M

Select item 365508811.

Novel HSP90 inhibitor NVP-HSP990 targets cell cycle regulators to ablate Olig2-positive glioma tumor initiating cells

Jun Fu, Dimpy Koul, Jun Yao, Shuzhen Wang, Ying Yuan, Howard Colman, Erik. P. Sulman, Frederick. F. Lang, W.K. Alfred Yung

Cancer Res. Author manuscript; available in PMC 2014 May 15.

Published in final edited form as: Cancer Res. 2013 May 15; 73(10): 3062–3074. Published online 2013 Mar 14. doi: 10.1158/0008-5472.CAN-12-2033

Retraction in:: Cancer Res. 2014 Nov 15; 74(22): 6731–6732.

PMCID:: PMC3655088

Abstract Article

Select item 359990512.

Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990

Dušan Milanović, Elke Firat, Anca Ligia Grosu, Gabriele Niedermann

Radiat Oncol. 2013; 8: 42. Published online 2013 Feb 28. doi: 10.1186/1748-717X-8-42

PMCID:: PMC3599905

Abstract Article PDF–863K

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