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Items: 1 to 20 of 93

1.
Sinomenine Alleviates Rheumatoid Arthritis by Suppressing the PI3K-Akt Signaling Pathway, as Demonstrated Through Network Pharmacology, Molecular Docking, and Experimental Validation
Qingyang Liu, Jian Wang, Chunhui Ding, Ying Chu, Fengying Jiang, Yunxia Hu, Haifeng Li, Qiubo Wang
Drug Des Devel Ther. 2024; 18: 3523–3545. Published online 2024 Aug 6. doi: 10.2147/DDDT.S475959
PMCID:
PMC11317229
AbstractArticlePDF–22M
2.
Antioxidant Activity and the Therapeutic Effect of Sinomenine Hydrochloride-Loaded Liposomes-in-Hydrogel on Atopic Dermatitis
Xue Chen, Yang Wu, Ruoyang Jia, Yuqing Fang, Keang Cao, Xinying Yang, Xiaobo Qu, Hongmei Xia
Int J Mol Sci. 2024 Jul; 25(14): 7676. Published online 2024 Jul 12. doi: 10.3390/ijms25147676
PMCID:
PMC11276951
AbstractArticlePDF–13M
3.
Graphene oxide quantum dots-loaded sinomenine hydrochloride nanocomplexes for effective treatment of rheumatoid arthritis via inducing macrophage repolarization and arresting abnormal proliferation of fibroblast-like synoviocytes
Ye Lin, Yuanyuan Tang, Ouyang Yi, Junping Zhu, Zhaoli Su, Gejing Li, Hua Zhou, Liang Liu, Bin Liu, Xiong Cai
J Nanobiotechnology. 2024; 22: 383. Published online 2024 Jul 1. doi: 10.1186/s12951-024-02645-8
PMCID:
PMC11218134
AbstractArticlePDF–17M
4.
High‐dose sinomenine attenuates ischemia/reperfusion‐induced hepatic inflammation and oxidative stress in rats with diabetes mellitus
Bo Hui, Xiaogang Zhang, Dinghui Dong, Yantao Shu, Ren Li, Zhengan Yang
Immun Inflamm Dis. 2024 Jun; 12(6): e1271. Published online 2024 Jun 18. doi: 10.1002/iid3.1271
PMCID:
PMC11184649
AbstractArticlePDF–1.2M
5.
Sinomenine treats rheumatoid arthritis by inhibiting MMP9 and inflammatory cytokines expression: bioinformatics analysis and experimental validation
Jinfang Luo, Yi Zhu, Yang Yu, Yujie Chen, Kang He, Jianxin Liu
Sci Rep. 2024; 14: 12786. Published online 2024 Jun 4. doi: 10.1038/s41598-024-61769-x
PMCID:
PMC11151427
AbstractArticlePDF–14M
6.
Sinomenine attenuates pulmonary fibrosis by downregulating TGF-β1/Smad3, PI3K/Akt and NF-κB signaling pathways
Fuqiang Yao, Minghao Xu, Lingjun Dong, Xiao Shen, Yujie Shen, Yisheng Jiang, Ting Zhu, Chu Zhang, Guangmao Yu
BMC Pulm Med. 2024; 24: 229. Published online 2024 May 10. doi: 10.1186/s12890-024-03050-5
PMCID:
PMC11088103
AbstractArticlePDF–20M
7.
Sinomenine Hydrochloride Protects IgA Nephropathy Through Regulating Cell Growth and Apoptosis of T and B Lymphocytes
Jun-Jian Li, Li Li, Shuang Li, Xin-Yi Tang, Hui-Feng Sun, Jian-Xin Liu
Drug Des Devel Ther. 2024; 18: 1247–1262. Published online 2024 Apr 17. doi: 10.2147/DDDT.S449119
PMCID:
PMC11032719
AbstractArticlePDF–11M
8.
Sinomenine hydrochloride enhancement of the inhibitory effects of anti-transferrin receptor antibody-dependent on the COX-2 pathway in human hepatoma cells
Yi Hong, Juan Yang, Xin Shen, Huifen Zhu, Xiaoxu Sun, Xue Wen, Jing Bian, Heyu Hu, Lu Yuan, Juan Tao, Ping Lei, Guanxin Shen
Cancer Immunol Immunother. 2013 Mar; 62(3): 447–454. Published online 2012 Sep 2. doi: 10.1007/s00262-012-1337-y
PMCID:
PMC11028739
AbstractArticlePDF–665K
9.
Bone protective effect of sinomenine against monosodium iodoacetate induced knee and hip injury in rat model: an inflammatory pathway
Yi-Hao Lei, Xing-Xi Hu, Hong-Jie Wen, Yong-Cheng Deng, Jun-Liang Jiang, Qing-Gang Zhao
Acta Cir Bras. 2024; 39: e390924. Published online 2024 Feb 5. doi: 10.1590/acb390924
PMCID:
PMC10852535
AbstractArticlePDF–346K
10.
Bioactivities and Mechanisms of Action of Sinomenine and Its Derivatives: A Comprehensive Review
Wen Hou, Lejun Huang, Hao Huang, Shenglan Liu, Wei Dai, Jianhong Tang, Xiangzhao Chen, Xiaolu Lu, Qisheng Zheng, Zhinuo Zhou, Ziyun Zhang, Jinxia Lan
Molecules. 2024 Jan; 29(2): 540. Published online 2024 Jan 22. doi: 10.3390/molecules29020540
PMCID:
PMC10818773
AbstractArticlePDF–4.5M
11.
Efficacy and safety of sinomenine for diabetic kidney diseases: A meta-analysis
Ying-Jie Zhang, Zong-Jie Shang, Mei Zheng, Ran Shi
Medicine (Baltimore) 2023 Dec 29; 102(52): e36779. Published online 2023 Dec 29. doi: 10.1097/MD.0000000000036779
PMCID:
PMC10754606
AbstractArticlePDF–2.4M
12.
Integrated multi-omics and bioinformatic methods to reveal the mechanisms of sinomenine against diabetic nephropathy
Yan Li, Lei Wang, Jimin Zhang, Bojun Xu, Huakui Zhan
BMC Complement Med Ther. 2023; 23: 287. Published online 2023 Aug 14. doi: 10.1186/s12906-023-04119-0
PMCID:
PMC10424381
AbstractArticlePDF–5.8M
13.
Sinomenine ameliorates adjuvant-induced arthritis by inhibiting the autophagy/NETosis/inflammation axis
H. Jiang, Q. Lu, J. Xu, G. Huo, Y. Cai, S. Geng, H. Xu, J. Zhang, H. Li, K. Yuan, G. Huang
Sci Rep. 2023; 13: 3933. Published online 2023 Mar 9. doi: 10.1038/s41598-023-30922-3
PMCID:
PMC9998614
AbstractArticlePDF–15M
14.
Sinomenine alleviates diabetic peripheral neuropathic pain through inhibition of the inositol‐requiring enzyme 1 alpha–X‐box binding protein 1 pathway by downregulating prostaglandin‐endoperoxide synthase 2
Ji Chen, Peng Guo, Xinxin Liu, Huizhi Liao, Kemin Chen, Yuxia Wang, Jie Qin, Fengrui Yang
J Diabetes Investig. 2023 Mar; 14(3): 364–375. Published online 2023 Jan 24. doi: 10.1111/jdi.13938
PMCID:
PMC9951574
AbstractArticlePDF–2.0M
15.
Effects of external acupoint therapy using sinomenine powder against rheumatoid arthritis based on pharmacokinetic and pharmacodynamic fitting
Haotian Bai, Rui Wang, Bixi Guan, Yongji Li, Yunlei Huang, Jing Yang
Chin Med J (Engl) 2022 Nov 5; 135(21): 2637–2639. Published online 2022 Mar 9. doi: 10.1097/CM9.0000000000002048
PMCID:
PMC9945214
ArticlePDF–745K
16.
Benefit-risk assessment of traditional Chinese medicine preparations of sinomenine using multicriteria decision analysis (MCDA) for patients with rheumatoid arthritis
Gao Xiang, Min Gao, Huirong Qin, Xiaolan Shen, Huilian Huang, Xiaoqiang Hou, Zhitao Feng
BMC Complement Med Ther. 2023; 23: 37. Published online 2023 Feb 6. doi: 10.1186/s12906-023-03864-6
PMCID:
PMC9901080
AbstractArticlePDF–1.5M
17.
Sinomenine Hydrochloride Can Ameliorate Benign Prostatic Hyperplasia by Lowering the 5α-Reductase 2 Level and Regulating the Balance between the Proliferation and Apoptosis of Cells
Mao-Si Fan, Yue-Fei Xia, Rui-Han Ye, Ze-Rui Sun, Ming-Yue Wang, Meng-Fei An, Shao-Shi Zhang, Li-Juan Zhang, Yun-Li Zhao, Ze-Min Xiang, Jun Sheng
Molecules. 2023 Jan; 28(2): 803. Published online 2023 Jan 13. doi: 10.3390/molecules28020803
PMCID:
PMC9867214
AbstractArticlePDF–2.7M
18.
Towards Better Sinomenine-Type Drugs to Treat Rheumatoid Arthritis: Molecular Mechanisms and Structural Modification
Cuili Zhang, Shujie Zhang, Jingjing Liao, Zipeng Gong, Xin Chai, Haining Lyu
Molecules. 2022 Dec; 27(24): 8645. Published online 2022 Dec 7. doi: 10.3390/molecules27248645
PMCID:
PMC9781648
AbstractArticlePDF–1.0M
19.
Sinomenine pretreatment alleviates hepatic ischemia/reperfusion injury through activating Nrf‐2/HO‐1 pathway
Bo Hui, Yantao Shu, Dandan Yang, Zhidong Wang, Li Zhang, Nina Lei, Zhengan Yang
Immun Inflamm Dis. 2022 Oct; 10(10): e700. Published online 2022 Sep 28. doi: 10.1002/iid3.700
PMCID:
PMC9517062
AbstractArticlePDF–1.7M
20.
Sinomenine Hydrochloride Promotes TSHR-Dependent Redifferentiation in Papillary Thyroid Cancer
Jing Zhang, Aomei Zhao, Xi Jia, Xinru Li, Yiqian Liang, Yan Liu, Xin Xie, Xijie Qu, Qi Wang, Yuemin Zhang, Rui Gao, Yan Yu, Aimin Yang
Int J Mol Sci. 2022 Sep; 23(18): 10709. Published online 2022 Sep 14. doi: 10.3390/ijms231810709
PMCID:
PMC9500915
AbstractArticlePDF–2.3M

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