PMC Links for OMIM (Select 606831) - PMC

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Items: 12

Select item 73363021.

NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma

Jeannette L. Tenthorey, Roberto A. Chavez, Thornton W. Thompson, Katherine A. Deets, Russell E. Vance, Isabella Rauch

J Exp Med. 2020 Jul 6; 217(7): e20191736. Published online 2020 Apr 27. doi: 10.1084/jem.20191736

PMCID:: PMC7336302

Abstract Article PDF–2.0M

Select item 68151402.

HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4

Akhouri Kishore Raghawan, Rajashree Ramaswamy, Vegesna Radha, Ghanshyam Swarup

Proc Natl Acad Sci U S A. 2019 Oct 22; 116(43): 21694–21703. Published online 2019 Oct 9. doi: 10.1073/pnas.1905261116

PMCID:: PMC6815140

Abstract Article PDF–1.8M

Select item 59355773.

IRF8 regulates transcription of Naips for NLRC4 inflammasome activation

Rajendra Karki, Ein Lee, David Place, Parimal Samir, Jayadev Mavuluri, Bhesh Raj Sharma, Arjun Balakrishnan, R. K. Subbarao Malireddi, Rechel Geiger, Qifan Zhu, Geoffrey Neale, Thirumala-Devi Kanneganti

Cell. Author manuscript; available in PMC 2019 May 3.

Published in final edited form as: Cell. 2018 May 3; 173(4): 920–933.e13. Published online 2018 Mar 22. doi: 10.1016/j.cell.2018.02.055

PMCID:: PMC5935577

Abstract Article PDF–2.0M

Select item 47884084.

Prevention and cure of rotavirus infection via TLR5/NLRC4–mediated production of IL-22 and IL-18

Benyue Zhang, Benoit Chassaing, Zhenda Shi, Robin Uchiyama, Zhan Zhang, Timothy L. Denning, Sue E. Crawford, Andrea J. Pruijssers, Jason A. Iskarpatyoti, Mary K. Estes, Terence S. Dermody, Wenjun Ouyang, Ifor R. Williams, Matam Vijay-Kumar, Andrew T. Gewirtz

Science. Author manuscript; available in PMC 2016 Mar 11.

Published in final edited form as: Science. 2014 Nov 14; 346(6211): 861–865. doi: 10.1126/science.1256999

PMCID:: PMC4788408

Abstract Article PDF–471K

Select item 47328725.

Disease tolerance mediated by commensal E. coli via inflammasome and IGF-1 signaling

Alexandria M. Palaferri Schieber, Yujung Michelle Lee, Max W. Chang, Mathias Leblanc, Brett Collins, Michael Downes, Ronald M. Evans, Janelle S. Ayres

Science. Author manuscript; available in PMC 2016 Oct 30.

Published in final edited form as: Science. 2015 Oct 30; 350(6260): 558–563. doi: 10.1126/science.aac6468

PMCID:: PMC4732872

Abstract Article PDF–1.5M

Select item 46401896.

Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization

Liman Zhang, Shuobing Chen, Jianbin Ruan, Jiayi Wu, Alexander B. Tong, Qian Yin, Yang Li, Liron David, Alvin Lu, Wei Li Wang, Carolyn Marks, Qi Ouyang, Xinzheng Zhang, Youdong Mao, Hao Wu

Science. Author manuscript; available in PMC 2015 Nov 10.

Published in final edited form as: Science. 2015 Oct 23; 350(6259): 404–409. Published online 2015 Oct 8. doi: 10.1126/science.aac5789

PMCID:: PMC4640189

Abstract Article PDF–1.0M

Select item 42356347.

An inherited mutation in NLRC4 causes autoinflammation in human and mice

Akiko Kitamura, Yuki Sasaki, Takaya Abe, Hirotsugu Kano, Koji Yasutomo

J Exp Med. 2014 Nov 17; 211(12): 2385–2396. doi: 10.1084/jem.20141091

PMCID:: PMC4235634

Abstract Article PDF–2.3M

Select item 41773698.

An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome

Scott W. Canna, Adriana Almeida de Jesus, Sushanth Gouni, Stephen R. Brooks, Bernadette Marrero, Yin Liu, Michael A. DiMattia, Kristien J.M. Zaal, Gina A. Montealegre Sanchez, Hanna Kim, Dawn Chapelle, Nicole Plass, Yan Huang, Alejandro V. Villarino, Angelique Biancotto, Thomas A. Fleisher, Joseph A. Duncan, John J O’Shea, Susanne Benseler, Alexei Grom, Zuoming Deng, Ronald M Laxer, Raphaela Goldbach-Mansky

Nat Genet. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Nat Genet. 2014 Oct; 46(10): 1140–1146. Published online 2014 Sep 14. doi: 10.1038/ng.3089

PMCID:: PMC4177369

Abstract Article PDF–2.2M

Select item 41773679.

Mutation of NLRC4 causes a syndrome of enterocolitis and autoinflammation

Neil Romberg, Khatoun Al Moussawi, Carol Nelson-Williams, Amy L Stiegler, Erin Loring, Murim Choi, John Overton, Eric Meffre, Mustafa K Khokha, Anita J Huttner, Brian West, Nikolai A Podoltsev, Titus J Boggon, Barbara I Kazmierczak, Richard P Lifton

Nat Genet. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Nat Genet. 2014 Oct; 46(10): 1135–1139. Published online 2014 Sep 14. doi: 10.1038/ng.3066

PMCID:: PMC4177367

Abstract Article PDF–1.5M

Select item 346548310.

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

Jakob von Moltke, Norver J. Trinidad, Mahtab Moayeri, Alexander F. Kintzer, Samantha B. Wang, Nico van Rooijen, Charles R. Brown, Bryan A. Krantz, Stephen H. Leppla, Karsten Gronert, Russell E. Vance

Nature. Author manuscript; available in PMC 2013 Apr 4.

Published in final edited form as: Nature. 2012 Oct 4; 490(7418): 107–111. Published online 2012 Aug 19. doi: 10.1038/nature11351