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Items: 1 to 20 of 47

1.
Evolutionary dynamics of Clostridium difficile over short and long time scales
Miao He, Mohammed Sebaihia, Trevor D. Lawley, Richard A. Stabler, Lisa F. Dawson, Melissa J. Martin, Kathryn E. Holt, Helena M.B. Seth-Smith, Michael A. Quail, Richard Rance, Karen Brooks, Carol Churcher, David Harris, Stephen D. Bentley, Christine Burrows, Louise Clark, Craig Corton, Vicky Murray, Graham Rose, Scott Thurston, Andries van Tonder, Danielle Walker, Brendan W. Wren, Gordon Dougan, Julian Parkhill
Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16): 7527–7532. Published online 2010 Apr 5. doi: 10.1073/pnas.0914322107
PMCID:
PMC2867753
AbstractArticlePDF–772K
2.
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium
Richard A Stabler, Miao He, Lisa Dawson, Melissa Martin, Esmeralda Valiente, Craig Corton, Trevor D Lawley, Mohammed Sebaihia, Michael A Quail, Graham Rose, Dale N Gerding, Maryse Gibert, Michel R Popoff, Julian Parkhill, Gordon Dougan, Brendan W Wren
Genome Biol. 2009; 10(9): R102. Published online 2009 Sep 25. doi: 10.1186/gb-2009-10-9-r102
PMCID:
PMC2768977
AbstractArticlePDF–1.2M
3.
Expanding the repertoire of conservative site-specific recombination in Clostridioides difficile
Ognjen Sekulovic, Jacob Bourgeois, Aimee Shen, Andrew Camilli
Anaerobe. Author manuscript; available in PMC 2019 Dec 18.
Published in final edited form as: Anaerobe. 2019 Dec; 60: 102073. Published online 2019 Jul 16. doi: 10.1016/j.anaerobe.2019.102073
PMCID:
PMC6917912
AbstractArticlePDF–520K
4.
Phase variation of a signal transduction system controls Clostridioides difficile colony morphology, motility, and virulence
Elizabeth M. Garrett, Ognjen Sekulovic, Daniela Wetzel, Joshua B. Jones, Adrianne N. Edwards, Germán Vargas-Cuebas, Shonna M. McBride, Rita Tamayo
PLoS Biol. 2019 Oct; 17(10): e3000379. Published online 2019 Oct 28. doi: 10.1371/journal.pbio.3000379
PMCID:
PMC6837544
AbstractArticlePDF–2.7M
5.
Hypervirulent clade 2, ribotype 019/sequence type 67 Clostridioides difficile strain from Japan
Ryoichi Saito, Yukino Usui, Alafate Ayibieke, Jun Nakajima, Isaac Prah, Kazunari Sonobe, Yoshibumi Aiso, Shiori Ito, Yasuhiro Itsui, Yoshiro Hadano, Yoko Nukui, Ryuji Koike, Shuji Tohda
Gut Pathog. 2019; 11: 54. Published online 2019 Nov 4. doi: 10.1186/s13099-019-0336-3
PMCID:
PMC6827173
AbstractArticlePDF–2.0M
6.
Clostridioides difficile Whole-Genome Sequencing Reveals Limited Within-Host Genetic Diversity in a Pediatric Cohort
Aakash Balaji, Egon A. Ozer, Larry K. Kociolek
J Clin Microbiol. 2019 Sep; 57(9): e00559-19. Prepublished online 2019 Jul 17. Published online 2019 Aug 26. doi: 10.1128/JCM.00559-19
PMCID:
PMC6711918
AbstractArticlePDF–553K
7.
A global to local genomics analysis of Clostridioides difficile ST1/RT027 identifies cryptic transmission events in a northern Arizona healthcare network
Charles H. D. Williamson, Nathan E. Stone, Amalee E. Nunnally, Heidie M. Hornstra, David M. Wagner, Chandler C. Roe, Adam J. Vazquez, Nivedita Nandurkar, Jacob Vinocur, Joel Terriquez, John Gillece, Jason Travis, Darrin Lemmer, Paul Keim, Jason W. Sahl
Microb Genom. 2019 Jul; 5(7): e000271. Published online 2019 May 20. doi: 10.1099/mgen.0.000271
PMCID:
PMC6700662
AbstractArticlePDF–1.7M
8.
Toxin B Variants from Clostridium difficile Strains VPI 10463 and NAP1/027 Share Similar Substrate Profile and Cellular Intoxication Kinetics but Use Different Host Cell Entry Factors
Diana López-Ureña, Josué Orozco-Aguilar, Yendry Chaves-Madrigal, Andrea Ramírez-Mata, Amanda Villalobos-Jimenez, Stefan Ost, Carlos Quesada-Gómez, César Rodríguez, Panagiotis Papatheodorou, Esteban Chaves-Olarte
Toxins (Basel) 2019 Jun; 11(6): 348. Published online 2019 Jun 17. doi: 10.3390/toxins11060348
PMCID:
PMC6628394
AbstractArticlePDF–2.8M
9.
Whole-genome sequencing reveals nosocomial Clostridioides difficile transmission and a previously unsuspected epidemic scenario
Sergio García-Fernández, Martinique Frentrup, Matthias Steglich, Aitor Gonzaga, Marta Cobo, Nieves López-Fresneña, Javier Cobo, María-Isabel Morosini, Rafael Cantón, Rosa del Campo, Ulrich Nübel
Sci Rep. 2019; 9: 6959. Published online 2019 May 6. doi: 10.1038/s41598-019-43464-4
PMCID:
PMC6502822
AbstractArticlePDF–1.0M
10.
Environmental transmission of Clostridioides difficile ribotype 027 at a long-term care facility; an outbreak investigation guided by whole genome sequencing
Bradley T. Endres, Kierra M. Dotson, Kelley Poblete, Jacob McPherson, Chris Lancaster, Eugénie Bassères, Ali Memariani, Sandi Arnold, Shawn Tupy, Conner Carlsen, Bonnie Morehead, Sophia Anyatonwu, Christa Cook, Khurshida Begum, M. Jahangir Alam, Kevin W. Garey
Infect Control Hosp Epidemiol. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: Infect Control Hosp Epidemiol. 2018 Nov; 39(11): 1322–1329. Published online 2018 Sep 26. doi: 10.1017/ice.2018.230
PMCID:
PMC6423542
AbstractArticlePDF–619K
11.
RstA Is a Major Regulator of Clostridioides difficile Toxin Production and Motility
Adrianne N. Edwards, Brandon R. Anjuwon-Foster, Shonna M. McBride
mBio. 2019 Mar-Apr; 10(2): e01991-18. Published online 2019 Mar 12. doi: 10.1128/mBio.01991-18
PMCID:
PMC6414698
AbstractArticlePDF–4.7M
12.
In silico simulations of occurrence of transcription factor binding sites in bacterial genomes
Jan Mrázek, Anna C. Karls
BMC Evol Biol. 2019; 19: 67. Published online 2019 Mar 1. doi: 10.1186/s12862-019-1381-8
PMCID:
PMC6397444
AbstractArticlePDF–1.8M
13.
Epidemic Clostridioides difficile Ribotype 027 Lineages: Comparisons of Texas Versus Worldwide Strains
Bradley T Endres, Khurshida Begum, Hua Sun, Seth T Walk, Ali Memariani, Chris Lancaster, Anne J Gonzales-Luna, Kierra M Dotson, Eugénie Bassères, Charlene Offiong, Shawn Tupy, Kristi Kuper, Edward Septimus, Raouf Arafat, M Jahangir Alam, Zhongming Zhao, Julian G Hurdle, Tor C Savidge, Kevin W Garey
Open Forum Infect Dis. 2019 Feb; 6(2): ofz013. Published online 2019 Feb 9. doi: 10.1093/ofid/ofz013
PMCID:
PMC6368847
AbstractArticlePDF–671K
14.
PrsA2 (CD630_35000) of Clostridioides difficile Is an Active Parvulin-Type PPIase and a Virulence Modulator
Can Murat Ünal, Mareike Berges, Nathiana Smit, Cordelia Schiene-Fischer, Christina Priebe, Till Strowig, Dieter Jahn, Michael Steinert
Front Microbiol. 2018; 9: 2913. Published online 2018 Dec 4. doi: 10.3389/fmicb.2018.02913
PMCID:
PMC6288519
AbstractArticlePDF–3.0M
15.
Novel Clade C-I Clostridium difficile strains escape diagnostic tests, differ in pathogenicity potential and carry toxins on extrachromosomal elements
Gabriel Ramírez-Vargas, Diana López-Ureña, Adriana Badilla, Josué Orozco-Aguilar, Tatiana Murillo, Priscilla Rojas, Thomas Riedel, Jörg Overmann, Gabriel González, Esteban Chaves-Olarte, Carlos Quesada-Gómez, César Rodríguez
Sci Rep. 2018; 8: 13951. Published online 2018 Sep 17. doi: 10.1038/s41598-018-32390-6
PMCID:
PMC6141592
AbstractArticlePDF–3.5M
16.
Clostridium difficile Whole Genome Sequencing Reveals Limited Transmission Among Symptomatic Children: A Single-Center Analysis
Larry K Kociolek, Dale N Gerding, Robyn O Espinosa, Sameer J Patel, Stanford T Shulman, Egon A Ozer
Clin Infect Dis. 2018 Jul 15; 67(2): 229–234. Published online 2018 Jan 23. doi: 10.1093/cid/ciy060
PMCID:
PMC6030871
AbstractArticlePDF–1.3M
17.
The Binary Toxin CDT of Clostridium difficile as a Tool for Intracellular Delivery of Bacterial Glucosyltransferase Domains
Lara-Antonia Beer, Helma Tatge, Carmen Schneider, Maximilian Ruschig, Michael Hust, Jessica Barton, Stefan Thiemann, Viola Fühner, Giulio Russo, Ralf Gerhard
Toxins (Basel) 2018 Jun; 10(6): 225. Published online 2018 Jun 1. doi: 10.3390/toxins10060225
PMCID:
PMC6024811
AbstractArticlePDF–2.2M
18.
Characterization of Flagellum and Toxin Phase Variation in Clostridioides difficile Ribotype 012 Isolates
Brandon R. Anjuwon-Foster, Natalia Maldonado-Vazquez, Rita Tamayo
J Bacteriol. 2018 Jul 15; 200(14): e00056-18. Prepublished online 2018 May 7. Published online 2018 Jun 25. doi: 10.1128/JB.00056-18
PMCID:
PMC6018351
AbstractArticlePDF–1.9M
19.
Convergent Loss of ABC Transporter Genes From Clostridioides difficile Genomes Is Associated With Impaired Tyrosine Uptake and p-Cresol Production
Matthias Steglich, Julia D. Hofmann, Julia Helmecke, Johannes Sikorski, Cathrin Spröer, Thomas Riedel, Boyke Bunk, Jörg Overmann, Meina Neumann-Schaal, Ulrich Nübel
Front Microbiol. 2018; 9: 901. Published online 2018 May 8. doi: 10.3389/fmicb.2018.00901
PMCID:
PMC5951980
AbstractArticlePDF–1.6M
20.
Phase variation of Clostridium difficile virulence factors
Brandon R. Anjuwon-Foster, Rita Tamayo
Gut Microbes. 2018; 9(1): 76–83. Published online 2017 Sep 21. doi: 10.1080/19490976.2017.1362526
PMCID:
PMC5914908
AbstractArticlePDF–518K

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