PMC Links for Nucleotide (Select 1780222532) - PMC

Select item 64331201.

MEK drives BRAF activation through allosteric control of KSR proteins

Hugo Lavoie, Malha Sahmi, Pierre Maisonneuve, Sara A. Marullo, Neroshan Thevakumaran, Ting Jin, Igor Kurinov, Frank Sicheri, Marc Therrien

Nature. Author manuscript; available in PMC 2019 Mar 25.

Published in final edited form as: Nature. 2018 Feb 22; 554(7693): 549–553. Published online 2018 Feb 12. doi: 10.1038/nature25478

PMCID:: PMC6433120

Abstract Article PDF–2.4M

Select item 60813822.

Intrinsically active MEK variants are differentially regulated by proteinases and phosphatases

Merav Ordan, Chiara Pallara, Galia Maik-Rachline, Tamar Hanoch, Francesco Luigi Gervasio, Fabian Glaser, Juan Fernandez-Recio, Rony Seger

Sci Rep. 2018; 8: 11830. Published online 2018 Aug 7. doi: 10.1038/s41598-018-30202-5

PMCID:: PMC6081382

Abstract Article PDF–4.8M

Select item 56186823.

p53 regulates ERK1/2/CREB cascade via a novel SASH1/MAP2K2 crosstalk to induce hyperpigmentation

Ding'an Zhou, Zhongshu Kuang, Xing Zeng, Ke Wang, Jiangshu Ma, Huangchao Luo, Mei Chen, Yan Li, Jiawei Zeng, Shu Li, Fujun Luan, Yong He, Hongying Dai, Beizhong Liu, Hui Li, Lin He, Qinghe Xing

J Cell Mol Med. 2017 Oct; 21(10): 2465–2480. Published online 2017 Apr 6. doi: 10.1111/jcmm.13168

PMCID:: PMC5618682

Abstract Article PDF–5.5M

Select item 55316114.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 3949915.

Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1.

D R Alessi, Y Saito, D G Campbell, P Cohen, G Sithanandam, U Rapp, A Ashworth, C J Marshall, S Cowley

EMBO J. 1994 Apr 1; 13(7): 1610–1619. doi: 10.1002/j.1460-2075.1994.tb06424.x

PMCID:: PMC394991

Summary Page Browse PDF–2.1M

Select item 3600946.

Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1.

D L Charest, G Mordret, K W Harder, F Jirik, S L Pelech

Mol Cell Biol. 1993 Aug; 13(8): 4679–4690. doi: 10.1128/mcb.13.8.4679

PMCID:: PMC360094

Summary Page Browse PDF–3.8M

Select item 69776867.

Lycorine Induces autophagy-associated apoptosis by targeting MEK2 and enhances vemurafenib activity in colorectal cancer

Man Hu, Zhaomin Yu, Peiyuan Mei, Jinxiao Li, Dan Luo, Haiming Zhang, Minfeng Zhou, Fengxia Liang, Rui Chen

Aging (Albany NY) 2020 Jan 15; 12(1): 138–155. Published online 2020 Jan 3. doi: 10.18632/aging.102606

Correction in:: Aging (Albany NY). 2020 Apr 15; 12(7): 6488–6489.

PMCID:: PMC6977686

Abstract Article PDF–5.4M

Select item 67215878.

Long Non-Coding RNAs Target Pathogenetically Relevant Genes and Pathways in Rheumatoid Arthritis

Marzia Dolcino, Elisa Tinazzi, Antonio Puccetti, Claudio Lunardi

Cells. 2019 Aug; 8(8): 816. Published online 2019 Aug 2. doi: 10.3390/cells8080816

PMCID:: PMC6721587

Abstract Article PDF–1.0M

Select item 57886499.

Gene master regulators of papillary and anaplastic thyroid cancers

Dumitru A. Iacobas, Neha Y. Tuli, Sanda Iacobas, John K. Rasamny, Augustine Moscatello, Jan Geliebter, Raj K. Tiwari

Oncotarget. 2018 Jan 5; 9(2): 2410–2424. Published online 2017 Dec 19. doi: 10.18632/oncotarget.23417

PMCID:: PMC5788649

Abstract Article PDF–7.4M

Select item 544810210.

The WW domain of the scaffolding protein IQGAP1 is neither necessary nor sufficient for binding to the MAPKs ERK1 and ERK2

A. Jane Bardwell, Leonila Lagunes, Ronak Zebarjedi, Lee Bardwell

J Biol Chem. 2017 May 26; 292(21): 8750–8761. Published online 2017 Apr 10. doi: 10.1074/jbc.M116.767087

PMCID:: PMC5448102

Abstract Article PDF–2.8M

Select item 540687411.

Gene Expression Analysis before and after Treatment with Adalimumab in Patients with Ankylosing Spondylitis Identifies Molecular Pathways Associated with Response to Therapy

Marzia Dolcino, Elisa Tinazzi, Andrea Pelosi, Giuseppe Patuzzo, Francesca Moretta, Claudio Lunardi, Antonio Puccetti

Genes (Basel) 2017 Apr; 8(4): 127. Published online 2017 Apr 24. doi: 10.3390/genes8040127

PMCID:: PMC5406874

Abstract Article PDF–2.7M

Select item 460701312.

Mutation in NRAS in familial Noonan syndrome – case report and review of the literature

Sara Ekvall, Maria Wilbe, Jovanna Dahlgren, Eric Legius, Arie van Haeringen, Otto Westphal, Göran Annerén, Marie-Louise Bondeson

BMC Med Genet. 2015; 16: 95. Published online 2015 Oct 14. doi: 10.1186/s12881-015-0239-1

PMCID:: PMC4607013

Abstract Article PDF–1018K

Select item 459476713.

A conserved set of maternal genes? Insights from a molluscan transcriptome

M. MAUREEN LIU, JOHN W. DAVEY, DANIEL J. JACKSON, MARK L. BLAXTER, ANGUS DAVISON

Int J Dev Biol. Author manuscript; available in PMC 2015 Oct 6.

Published in final edited form as: Int J Dev Biol. 2014; 58(6-8): 501–511. doi: 10.1387/ijdb.140121ad

PMCID:: PMC4594767

Abstract Article PDF–1004K

Select item 441443414.

Alteration of gene expression profile following PPP2R5C knockdown may be associated with proliferation suppression and increased apoptosis of K562 cells

Sichu Liu, Qi Shen, Yu Chen, Chengwu Zeng, Changshu Cao, Lijian Yang, Shaohua Chen, Xiuli Wu, Bo Li, Yangqiu Li

J Hematol Oncol. 2015; 8: 34. Published online 2015 Apr 12. doi: 10.1186/s13045-015-0125-5

PMCID:: PMC4414434

Abstract Article PDF–707K

Select item 426987215.

Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation

Alessia Landi, Jolien Vermeire, Veronica Iannucci, Hanne Vanderstraeten, Evelien Naessens, Mostafa Bentahir, Bruno Verhasselt

Retrovirology. 2014; 11: 118. Published online 2014 Dec 13. doi: 10.1186/s12977-014-0118-4

PMCID:: PMC4269872

Abstract Article PDF–1.1M

Select item 418815216.

Clinical and Molecular Findings of Tunisian Patients with RASopathies

Rim Louati, N. Bouayed Abdelmoula, Imen Trabelsi, Dorra Abid, Christina Lissewski, Najla Kharrat, Samir Kamoun, Martin Zenker, Tarek Rebai

Mol Syndromol. 2014 Aug; 5(5): 212–217. Published online 2014 May 23. doi: 10.1159/000362898

PMCID:: PMC4188152

Abstract Article PDF–137K

Select item 301750317.

A Docking Site in MKK4 Mediates High Affinity Binding to JNK MAPKs and Competes with Similar Docking Sites in JNK Substrates

David T. Ho, A. Jane Bardwell, Mahsa Abdollahi, Lee Bardwell

J Biol Chem. Author manuscript; available in PMC 2011 Jan 7.

Published in final edited form as: J Biol Chem. 2003 Aug 29; 278(35): 32662–32672. Published online 2003 Jun 3. doi: 10.1074/jbc.M304229200

PMCID:: PMC3017503

Abstract Article PDF–2.4M

Select item 301749818.

Characterization of an ERK-binding Domain in Microphthalmia-associated Transcription Factor and Differential Inhibition of ERK2-mediated Substrate Phosphorylation

Douglas M. Molina, Seema Grewal, Lee Bardwell

J Biol Chem. Author manuscript; available in PMC 2011 Jan 7.

Published in final edited form as: J Biol Chem. 2005 Dec 23; 280(51): 42051–42060. Published online 2005 Oct 24. doi: 10.1074/jbc.M510590200

PMCID:: PMC3017498

Abstract Article PDF–1.6M

Select item 265282319.

Cardio‐facio‐cutaneous and Noonan syndromes due to mutations in the RAS/MAPK signalling pathway: genotype–phenotype relationships and overlap with Costello syndrome

Caroline Nava, Nadine Hanna, Caroline Michot, Sabrina Pereira, Nathalie Pouvreau, Tetsuya Niihori, Yoko Aoki, Yoichi Matsubara, Benoit Arveiler, Didier Lacombe, Eric Pasmant, Béatrice Parfait, Clarisse Baumann, Delphine Héron, Sabine Sigaudy, Annick Toutain, Marlène Rio, Alice Goldenberg, Bruno Leheup, Alain Verloes, Hélène Cavé

J Med Genet. 2007 Dec; 44(12): 763–771. Published online 2007 Aug 17. doi: 10.1136/jmg.2007.050450

PMCID:: PMC2652823

Abstract Article

Select item 140230520.

Increased therapeutic potential of an experimental anti-mitotic inhibitor SB715992 by genistein in PC-3 human prostate cancer cell line

David A Davis, Sarah H Sarkar, Maha Hussain, Yiwei Li, Fazlul H Sarkar

BMC Cancer. 2006; 6: 22. Published online 2006 Jan 24. doi: 10.1186/1471-2407-6-22

PMCID:: PMC1402305

Abstract Article PDF–1.0M

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