PMC Links for Nucleotide (Select 1708260631) - PMC

Select item 65808611.

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

Edmond M. Chan, Tsukasa Shibue, James M. McFarland, Benjamin Gaeta, Mahmoud Ghandi, Nancy Dumont, Alfredo Gonzalez, Justine S. McPartlan, Tianxia Li, Yanxi Zhang, Jie Bin Liu, Jean-Bernard Lazaro, Peili Gu, Cortt G. Piett, Annie Apffel, Syed O. Ali, Rebecca Deasy, Paula Keskula, Raymond W.S. Ng, Emma A. Roberts, Elizaveta Reznichenko, Lisa Leung, Maria Alimova, Monica Schenone, Mirazul Islam, Yosef E. Maruvka, Yang Liu, Jatin Roper, Srivatsan Raghavan, Marios Giannakis, Yuen-Yi Tseng, Zachary D. Nagel, Alan D’Andrea, David E. Root, Jesse S. Boehm, Gad Getz, Sandy Chang, Todd R. Golub, Aviad Tsherniak, Francisca Vazquez, Adam J. Bass

Nature. Author manuscript; available in PMC 2019 Oct 10.

Published in final edited form as: Nature. 2019 Apr; 568(7753): 551–556. Published online 2019 Apr 10. doi: 10.1038/s41586-019-1102-x

PMCID:: PMC6580861

Abstract Article PDF–5.0M

Select item 64681702.

ATM pathway activation limits R-loop-associated genomic instability in Werner syndrome cells

Veronica Marabitti, Giorgia Lillo, Eva Malacaria, Valentina Palermo, Massimo Sanchez, Pietro Pichierri, Annapaola Franchitto

Nucleic Acids Res. 2019 Apr 23; 47(7): 3485–3502. Published online 2019 Jan 18. doi: 10.1093/nar/gkz025

PMCID:: PMC6468170

Abstract Article PDF–11M

Select item 64266013.

Werner Helicase Control of Human Papillomavirus 16 E1-E2 DNA Replication Is Regulated by SIRT1 Deacetylation

Dipon Das, Molly L. Bristol, Nathan W. Smith, Claire D. James, Xu Wang, Pietro Pichierri, Iain M. Morgan

mBio. 2019 Mar-Apr; 10(2): e00263-19. Published online 2019 Mar 19. doi: 10.1128/mBio.00263-19

Correction in:: mBio. 2019 Jul-Aug; 10(4): e01635-19.

PMCID:: PMC6426601

Abstract Article PDF–2.9M

Select item 69330104.

Latin American Study of Hereditary Breast and Ovarian Cancer LACAM: A Genomic Epidemiology Approach

Javier Oliver, Rosalía Quezada Urban, Claudia Alejandra Franco Cortés, Clara Estela Díaz Velásquez, Ana Lorena Montealegre Paez, Rafael Adrián Pacheco-Orozco, Carlos Castro Rojas, Reggie García-Robles, Juan Javier López Rivera, Sandra Gaitán Chaparro, Ana Milena Gómez, Fernando Suarez Obando, Gustavo Giraldo, Maria Isabel Maya, Paula Hurtado-Villa, Ana Isabel Sanchez, Norma Serrano, Ana Isabel Orduz Galvis, Sandra Aruachan, Johanna Nuñez Castillo, Cecilia Frecha, Cecilia Riggi, Federico Jauk, Eva María Gómez García, Claudia Lorena Carranza, Vanessa Zamora, Gabriela Torres Mejía, Isabelle Romieu, Carlos Arturo Castañeda, Miluska Castillo, Rina Gitler, Adriana Antoniano, Ernesto Rojas Jiménez, Luis Enrique Romero Cruz, Fernando Vallejo Lecuona, Iván Delgado Enciso, Abril Bernardette Martínez Rizo, Alejandro Flores Carranza, Verónica Benites Godinez, Claudia Fabiola Méndez Catalá, Luis Alonso Herrera, Yolanda Irasema Chirino, Luis Ignacio Terrazas, Sandra Perdomo, Felipe Vaca Paniagua

Front Oncol. 2019; 9: 1429. Published online 2019 Dec 20. doi: 10.3389/fonc.2019.01429

PMCID:: PMC6933010

Abstract Article PDF–815K

Select item 52097255.

A comprehensive custom panel design for routine hereditary cancer testing: preserving control, improving diagnostics and revealing a complex variation landscape

Elisabeth Castellanos, Bernat Gel, Inma Rosas, Eva Tornero, Sheila Santín, Raquel Pluvinet, Juan Velasco, Lauro Sumoy, Jesús del Valle, Manuel Perucho, Ignacio Blanco, Matilde Navarro, Joan Brunet, Marta Pineda, Lidia Feliubadaló, Gabi Capellá, Conxi Lázaro, Eduard Serra

Sci Rep. 2017; 7: 39348. Published online 2017 Jan 4. doi: 10.1038/srep39348

PMCID:: PMC5209725

Abstract Article PDF–2.3M

Select item 50355686.

Transcriptome guided identification of novel functions of RECQ1 helicase

Xing Lu, Swetha Parvathaneni, Xiao Ling Li, Ashish Lal, Sudha Sharma

Methods. Author manuscript; available in PMC 2017 Oct 1.

Published in final edited form as: Methods. 2016 Oct 1; 108: 111–117. Published online 2016 Apr 18. doi: 10.1016/j.ymeth.2016.04.018

PMCID:: PMC5035568

Abstract Article PDF–1.4M

Select item 45246097.

A Novel WRN Frameshift Mutation Identified by Multiplex Genetic Testing in a Family with Multiple Cases of Cancer

Liu Yang, Guosheng Wang, Xinyi Zhao, Song Ye, Peng Shen, Weilin Wang, Shusen Zheng

PLoS One. 2015; 10(8): e0133020. Published online 2015 Aug 4. doi: 10.1371/journal.pone.0133020

PMCID:: PMC4524609

Abstract Article PDF–2.7M

Select item 43627248.

The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest

Julia M. Sidorova, Nianzhen Li, Albert Folch, Raymond J. Monnat, Jr

Cell Cycle. Author manuscript; available in PMC 2015 Mar 17.

Published in final edited form as: Cell Cycle. 2008 Mar 15; 7(6): 796–807. Published online 2008 Jan 4. doi: 10.4161/cc.7.6.5566

PMCID:: PMC4362724

Abstract Article PDF–911K

Select item 43151599.

Characterization of familial breast cancer in Saudi Arabia

Adnan Merdad, Mamdooh A Gari, Shireen Hussein, Shadi Al-Khayat, Hana Tashkandi, Jaudah Al-Maghrabi, Fatma Al-Thubaiti, Ibtessam R Hussein, Taha Koumosani, Nehad Shaer, Adeel G Chaudhary, Adel M Abuzenadah, Mohammed H Al-Qahtani, Ashraf Dallol

BMC Genomics. 2015; 16(Suppl 1): S3. Published online 2015 Jan 15. doi: 10.1186/1471-2164-16-S1-S3

PMCID:: PMC4315159

Abstract Article PDF–404K

Select item 430346310.

Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines

David CL Lam, Susan Y Luo, Wen Deng, Johnny SH Kwan, Jaime Rodriguez-Canales, Annie LM Cheung, Grace HW Cheng, Chi-Ho Lin, Ignacio I Wistuba, Pak C Sham, Thomas SK Wan, Sai-Wah Tsao

Onco Targets Ther. 2015; 8: 195–209. Published online 2015 Jan 16. doi: 10.2147/OTT.S71242

PMCID:: PMC4303463

Abstract Article PDF–4.9M

Select item 397229711.

Effects of Equol on Gene Expression in Female Cynomolgus Monkey Iliac Arteries

K Eyster, S. Appt, A. Chalpe, T. Register, T. Clarkson

Nutr Metab Cardiovasc Dis. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Nutr Metab Cardiovasc Dis. 2014 Apr; 24(4): 423–427. Published online 2013 Nov 1. doi: 10.1016/j.numecd.2013.09.014

PMCID:: PMC3972297

Abstract Article PDF–212K

Select item 395773512.

DNA Repair Pathways in Trypanosomatids: from DNA Repair to Drug Resistance

Marie-Michelle Genois, Eric R. Paquet, Marie-Claude N. Laffitte, Ranjan Maity, Amélie Rodrigue, Marc Ouellette, Jean-Yves Masson

Microbiol Mol Biol Rev. 2014 Mar; 78(1): 40–73. doi: 10.1128/MMBR.00045-13

PMCID:: PMC3957735

Abstract Article PDF–3.2M

Select item 311960013.

Differential gene expression in normal and transformed human mammary epithelial cells in response to oxidative stress

Diego F Cortes, Wei Sha, Valerie Hower, Greg Blekherman, Reinhard Laubenbacher, Steven Akman, Suzy V Torti, Vladimir Shulaev

Free Radic Biol Med. Author manuscript; available in PMC 2012 Jun 1.

Published in final edited form as: Free Radic Biol Med. 2011 Jun 1; 50(11): 1565–1574. Published online 2011 Mar 29. doi: 10.1016/j.freeradbiomed.2011.03.002

PMCID:: PMC3119600

Abstract Article PDF–529K

Select item 274889414.

Expression differences by continent of origin point to the immortalization process

Adam R. Davis, Isaac S. Kohane

Hum Mol Genet. 2009 Oct 15; 18(20): 3864–3875. Published online 2009 Jul 23. doi: 10.1093/hmg/ddp330

PMCID:: PMC2748894

Abstract Article PDF–425K

Select item 263975915.

Werner Syndrome Protein, WRN, Protects Cells from DNA Damage Induced by the Benzene Metabolite Hydroquinone

Xuefeng Ren, Sophia Lim, Martyn T. Smith, Luoping Zhang

Toxicol Sci. 2009 Feb; 107(2): 367–375. Published online 2008 Dec 8. doi: 10.1093/toxsci/kfn254

PMCID:: PMC2639759

Abstract Article PDF–521K

Select item 246474116.

Programmed Genetic Instability: A Tumor-Permissive Mechanism for Maintaining the Evolvability of Higher Species through Methylation-Dependent Mutation of DNA Repair Genes in the Male Germ Line

Yongzhong Zhao, Richard J. Epstein

Mol Biol Evol. 2008 Aug; 25(8): 1737–1749. Published online 2008 Jun 4. doi: 10.1093/molbev/msn126

PMCID:: PMC2464741

Abstract Article PDF–814K

Select item 242730417.

Monozygotic Twins Reveal Germline Contribution to Allelic Expression Differences

Vivian G. Cheung, Alan Bruzel, Joshua T. Burdick, Michael Morley, James L. Devlin, Richard S. Spielman

Am J Hum Genet. 2008 Jun 6; 82(6): 1357–1360. Published online 2008 May 30. doi: 10.1016/j.ajhg.2008.05.003

PMCID:: PMC2427304

Abstract Article PDF–323K

Select item 189541818.

Differential gene expression, GATA1 target genes, and the chemotherapy sensitivity of Down syndrome megakaryocytic leukemia

Yubin Ge, Alan A. Dombkowski, Katherine M. LaFiura, Dana Tatman, Ravikiran S. Yedidi, Mark L. Stout, Steven A. Buck, Gita Massey, David L. Becton, Howard J. Weinstein, Yaddanapudi Ravindranath, Larry H. Matherly, Jeffrey W. Taub

Blood. 2006 Feb 15; 107(4): 1570–1581. Prepublished online 2005 Oct 25. doi: 10.1182/blood-2005-06-2219