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Select item 62551851.

NOXA genetic amplification or pharmacologic induction primes lymphoma cells to BCL2 inhibitor-induced cell death

Yuxuan Liu, Patrizia Mondello, Tatiana Erazo, Neeta Bala Tannan, Zahra Asgari, Elisa de Stanchina, Gouri Nanjangud, Venkatraman E. Seshan, Shenqiu Wang, Hans-Guido Wendel, Anas Younes

Proc Natl Acad Sci U S A. 2018 Nov 20; 115(47): 12034–12039. Published online 2018 Nov 7. doi: 10.1073/pnas.1806928115

PMCID:: PMC6255185

Abstract Article PDF–1.1M

Select item 62402312.

Homoharringtonine interacts synergistically with bortezomib in NHL cells through MCL-1 and NOXA-dependent mechanisms

Tri Nguyen, Rebecca Parker, Yu Zhang, Elisa Hawkins, Maciej Kmieciak, William Craun, Steven Grant

BMC Cancer. 2018; 18: 1129. Published online 2018 Nov 16. doi: 10.1186/s12885-018-5018-x

PMCID:: PMC6240231

Abstract Article PDF–1.8M

Select item 62376023.

Repression of Noxa by Bmi1 contributes to deguelin‐induced apoptosis in non‐small cell lung cancer cells

Wei Li, Xinfang Yu, Zhenkun Xia, Xinyou Yu, Li Xie, Xiaolong Ma, Huiling Zhou, Lijun Liu, Jian Wang, Yifeng Yang, Haidan Liu

J Cell Mol Med. 2018 Dec; 22(12): 6213–6227. Published online 2018 Sep 25. doi: 10.1111/jcmm.13908

PMCID:: PMC6237602

Abstract Article PDF–3.1M

Select item 18877304.

BH3-only Protein Noxa Is a Mediator of Hypoxic Cell Death Induced by Hypoxia-inducible Factor 1α

Jee-Youn Kim, Hyun-Jong Ahn, Jong-Hoon Ryu, Kyoungho Suk, Jae-Hoon Park

J Exp Med. 2004 Jan 5; 199(1): 113–124. doi: 10.1084/jem.20030613

PMCID:: PMC1887730

Abstract Article PDF–390K

Select item 2479475.

Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line.

M Hijikata, N Kato, T Sato, Y Kagami, K Shimotohno

J Virol. 1990 Oct; 64(10): 4632–4639. doi: 10.1128/jvi.64.10.4632-4639.1990

PMCID:: PMC247947

Summary Page Browse PDF–2.1M

Select item 65490726.

Gene expression alterations of human liver cancer cells following borax exposure

Lun Wu, Ying Wei, Wen-Bo Zhou, You-Shun Zhang, Qin-Hua Chen, Ming-Xing Liu, Zheng-Peng Zhu, Jiao Zhou, Li-Hua Yang, Hong-Mei Wang, Guang-Min Wei, Sheng Wang, Zhi-Gang Tang

Oncol Rep. 2019 Jul; 42(1): 115–130. Published online 2019 May 23. doi: 10.3892/or.2019.7169

PMCID:: PMC6549072

Abstract Article PDF–852K

Select item 58337347.

BIM and NOXA are mitochondrial effectors of TAF6δ-driven apoptosis

Aurélie Delannoy, Emmanuelle Wilhelm, Sebastian Eilebrecht, Edith Milena Alvarado-Cuevas, Arndt G Benecke, Brendan Bell

Cell Death Dis. 2018 Feb; 9(2): 70. Published online 2018 Jan 22. doi: 10.1038/s41419-017-0115-3

PMCID:: PMC5833734

Abstract Article PDF–1.0M

Select item 57628438.

Measurement of BH3-only protein tolerance

Haiming Dai, Husheng Ding, Kevin L Peterson, X Wei Meng, Paula A Schneider, Katherine L B Knorr, Scott H Kaufmann

Cell Death Differ. 2018 Feb; 25(2): 282–293. Published online 2017 Oct 20. doi: 10.1038/cdd.2017.156

PMCID:: PMC5762843

Abstract Article PDF–4.6M

Select item 57599479.

Gene Expression Analysis Reveals the Concurrent Activation of Proapoptotic and Antioxidant-Defensive Mechanisms in Flavokawain B–Treated Cervical Cancer HeLa Cells

Swee Keong Yeap, Nadiah Abu, Nadeem Akthar, Wan Yong Ho, Huynh Ky, Sheau Wei Tan, Noorjahan Banu Alitheen, Tunku Kamarul

Integr Cancer Ther. 2017 Sep; 16(3): 373–384. Published online 2016 Jul 24. doi: 10.1177/1534735416660383

PMCID:: PMC5759947

Abstract Article PDF–1.0M

Select item 569782310.

Global transcriptome profile reveals abundance of DNA damage response and repair genes in individuals from high level natural radiation areas of Kerala coast

Vinay Jain, Birajalaxmi Das

PLoS One. 2017; 12(11): e0187274. Published online 2017 Nov 21. doi: 10.1371/journal.pone.0187274

PMCID:: PMC5697823

Abstract Article PDF–16M

Select item 564356311.

Screening for candidate genes related to breast cancer with cDNA microarray analysis

Yu-Juan Xiang, Qin-Ye Fu, Zhong-Bing Ma, De-Zong Gao, Qiang Zhang, Yu-Yang Li, Liang Li, Lu Liu, Chun-Miao Ye, Zhi-Gang Yu, Ming-Ming Guo

Chronic Dis Transl Med. 2015 Jun; 1(2): 65–72. Published online 2015 Mar 5. doi: 10.1016/j.cdtm.2015.02.001

PMCID:: PMC5643563

Abstract Article PDF–816K

Select item 547422312.

Histone Deacetylase Inhibitors Interrupt HSP90•RASGRP1 and HSP90•CRAF Interactions to Upregulate BIM and Circumvent Drug Resistance in Lymphoma Cells

Husheng Ding, Kevin L. Peterson, Cristina Correia, Brian Koh, Paula A. Schneider, Grzegorz S. Nowakowski, Scott H. Kaufmann

Leukemia. Author manuscript; available in PMC 2017 Jul 6.

Published in final edited form as: Leukemia. 2017 Jul; 31(7): 1593–1602. Published online 2016 Nov 28. doi: 10.1038/leu.2016.357

PMCID:: PMC5474223

Abstract Article PDF–1.2M

Select item 511146013.

The Evaluation and Comparison of Transcriptionally Targeted Noxa and Puma Killer Genes to Initiate Apoptosis Under Cancer-Specific Promoter CXCR1 in Hepatocarcinoma Gene Therapy

Shahryar Khoshtinat Nikkhoi, Hedieh Heydarzadeh, Saeed Ranjbar, Fatemeh Salimi, Masoud Aghaeifard, Seyed Moayed Alavian, Azadeh Reshadmanesh

Hepat Mon. 2016 Oct; 16(10): e38828. Published online 2016 Sep 19. doi: 10.5812/hepatmon.38828

PMCID:: PMC5111460

Abstract Article PDF–2.8M

Select item 461499014.

A knockdown with smoke model reveals FHIT as a repressor of Heme oxygenase 1

Jennifer A Boylston, Charles Brenner

Cell Cycle. 2014 Sep 15; 13(18): 2913–2930. Published online 2014 Oct 30. doi: 10.4161/15384101.2014.946858

PMCID:: PMC4614990

Abstract Article PDF–1.7M

Select item 441684915.

Heat Shock Inhibition of CDK5 Increases NOXA Levels through miR-23a Repression

Trevor M. Morey, Rabih Roufayel, Donald S. Johnston, Andrew S. Fletcher, Dick D. Mosser

J Biol Chem. 2015 May 1; 290(18): 11443–11454. Published online 2015 Mar 31. doi: 10.1074/jbc.M114.625988

PMCID:: PMC4416849

Abstract Article PDF–4.8M

Select item 434617816.

Genetics and Genomics of Endometriosis

Keith A. Hansen, Kathleen M. Eyster

Clin Obstet Gynecol. Author manuscript; available in PMC 2015 Mar 2.

Published in final edited form as: Clin Obstet Gynecol. 2010 Jun; 53(2): 403–412. doi: 10.1097/GRF.0b013e3181db7ca1

PMCID:: PMC4346178

Abstract Article PDF–135K

Select item 433320917.

Patterns of Gene Transcript Abundance in the Blood of Children with Severe or Uncomplicated Dengue Highlight Differences in Disease Evolution and Host Response to Dengue Virus Infection

Hoang Truong Long, Martin L. Hibberd, Tran Tinh Hien, Nguyen Minh Dung, Tran Van Ngoc, Jeremy Farrar, Bridget Wills, Cameron P. Simmons

J Infect Dis. Author manuscript; available in PMC 2015 Feb 19.

Published in final edited form as: J Infect Dis. 2009 Feb 15; 199(4): 537–546. doi: 10.1086/596507

PMCID:: PMC4333209

Abstract Article PDF–1.9M

Select item 411897918.

Evaluation of Genome-Wide Expression Profiles of Blood and Sputum Neutrophils in Cystic Fibrosis Patients Before and After Antibiotic Therapy

Massimo Conese, Stefano Castellani, Silvia Lepore, Orazio Palumbo, Antonio Manca, Teresa Santostasi, Angela Maria Polizzi, Massimiliano Copetti, Sante Di Gioia, Valeria Casavola, Lorenzo Guerra, Anna Diana, Pasqualina Montemurro, Maria Addolorata Mariggiò, Crescenzio Gallo, Angela Bruna Maffione, Massimo Carella

PLoS One. 2014; 9(8): e104080. Published online 2014 Aug 1. doi: 10.1371/journal.pone.0104080