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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 64985852.

Parkinson’s disease-associated LRRK2-G2019S mutant acts through regulation of SERCA activity to control ER stress in astrocytes

Jee Hoon Lee, Ji-hye Han, Hyunmi Kim, Sang Myun Park, Eun-hye Joe, Ilo Jou

Acta Neuropathol Commun. 2019; 7: 68. Published online 2019 May 2. doi: 10.1186/s40478-019-0716-4

PMCID:: PMC6498585

Abstract Article PDF–6.9M

Select item 63515653.

Mechanism of IRSp53 inhibition by 14-3-3

David J. Kast, Roberto Dominguez

Nat Commun. 2019; 10: 483. Published online 2019 Jan 29. doi: 10.1038/s41467-019-08317-8

PMCID:: PMC6351565

Abstract Article PDF–2.4M

Select item 58309164.

Chk1 and 14‐3‐3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest

Ruixue Yuan, Harmjan R Vos, Robert M van Es, Jing Chen, Boudewijn MT Burgering, Bart Westendorp, Alain de Bruin

EMBO J. 2018 Mar 1; 37(5): e97877. Published online 2018 Jan 23. doi: 10.15252/embj.201797877

PMCID:: PMC5830916

Abstract Article PDF–1.2M

Select item 56072415.

Chimeric 14-3-3 proteins for unraveling interactions with intrinsically disordered partners

Nikolai N. Sluchanko, Kristina V. Tugaeva, Sandra J. Greive, Alfred A. Antson

Sci Rep. 2017; 7: 12014. Published online 2017 Sep 20. doi: 10.1038/s41598-017-12214-9

PMCID:: PMC5607241

Abstract Article PDF–2.6M

Select item 2305736.

14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner.

N R Michaud, J R Fabian, K D Mathes, D K Morrison

Mol Cell Biol. 1995 Jun; 15(6): 3390–3397. doi: 10.1128/mcb.15.6.3390

PMCID:: PMC230573

Summary PDF–519K

Select item 407527.

Inhibition of phosphatidylinositol 3-kinase activity by association with 14-3-3 proteins in T cells.

N Bonnefoy-Bérard, Y C Liu, M von Willebrand, A Sung, C Elly, T Mustelin, H Yoshida, K Ishizaka, A Altman

Proc Natl Acad Sci U S A. 1995 Oct 24; 92(22): 10142–10146. doi: 10.1073/pnas.92.22.10142

PMCID:: PMC40752

Summary Page Browse PDF–1.3M

Select item 58497168.

A LATS biosensor screen identifies VEGFR as a regulator of the Hippo pathway in angiogenesis

T. Azad, H. J. Janse van Rensburg, E. D. Lightbody, B. Neveu, A. Champagne, A. Ghaffari, V. R. Kay, Y. Hao, H. Shen, B. Yeung, B. A. Croy, K. L. Guan, F. Pouliot, J. Zhang, C. J. B. Nicol, X. Yang

Nat Commun. 2018; 9: 1061. Published online 2018 Mar 13. doi: 10.1038/s41467-018-03278-w

PMCID:: PMC5849716

Abstract Article PDF–5.9M

Select item 49959719.

Site-specific phosphorylation and microtubule dynamics control Pyrin inflammasome activation

Wenqing Gao, Jieling Yang, Wang Liu, Yupeng Wang, Feng Shao

Proc Natl Acad Sci U S A. 2016 Aug 16; 113(33): E4857–E4866. Published online 2016 Aug 1. doi: 10.1073/pnas.1601700113

PMCID:: PMC4995971

Abstract Article PDF–1.5M

Select item 430571410.

Gene expression profiling reveals sequential changes in gastric tubular adenoma and carcinoma in situ

Chang-Hee Lee, Seung-Hyun Bang, Seung-Koo Lee, Kyu-Young Song, In-Chul Lee

World J Gastroenterol. 2005 Apr 7; 11(13): 1937–1945. Published online 2005 Apr 7. doi: 10.3748/wjg.v11.i13.1937

PMCID:: PMC4305714

Abstract Article PDF–686K

Select item 391137211.

Susceptibility to Acute Rheumatic Fever Based on Differential Expression of Genes Involved in Cytotoxicity, Chemotaxis, and Apoptosis

Penelope A. Bryant, Gordon K. Smyth, Travis Gooding, Alicia Oshlack, Zinta Harrington, Bart Currie, Jonathan R. Carapetis, Roy Robins-Browne, Nigel Curtis

Infect Immun. 2014 Feb; 82(2): 753–761. doi: 10.1128/IAI.01152-13

PMCID:: PMC3911372

Abstract Article PDF–1.0M

Select item 378330812.

Identification of Gene Expression Signature in Estrogen Receptor Positive Breast Carcinoma

Arvind D. Thakkar, Hemanth Raj, Debarshi Chakrabarti, Ravishankar, N. Saravanan, Bhaskaran Muthuvelan, Arun Balakrishnan, Muralidhara Padigaru

Biomark Cancer. 2010; 2: 1–15. Published online 2010 Feb 11. doi: 10.4137/BIC.S3793

PMCID:: PMC3783308

Abstract Article PDF–6.2M

Select item 366152013.

Global Gene Expression Profiling of Individual Human Oocytes and Embryos Demonstrates Heterogeneity in Early Development

Lisa Shaw, Sharon F. Sneddon, Leo Zeef, Susan J. Kimber, Daniel R. Brison

PLoS One. 2013; 8(5): e64192. Published online 2013 May 22. doi: 10.1371/journal.pone.0064192

PMCID:: PMC3661520

Abstract Article PDF–662K

Select item 338354014.

Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis

Jason E McDermott, Deborah L Diamond, Courtney Corley, Angela L Rasmussen, Michael G Katze, Katrina M Waters

BMC Syst Biol. 2012; 6: 28. Published online 2012 Apr 30. doi: 10.1186/1752-0509-6-28

PMCID:: PMC3383540

Abstract Article PDF–1.1M

Select item 295671015.

LNCaP Atlas: Gene expression associated with in vivo progression to castration-recurrent prostate cancer

Tammy L Romanuik, Gang Wang, Olena Morozova, Allen Delaney, Marco A Marra, Marianne D Sadar

BMC Med Genomics. 2010; 3: 43. Published online 2010 Sep 24. doi: 10.1186/1755-8794-3-43

PMCID:: PMC2956710

Abstract Article PDF–781K

Select item 295287116.

Identification of a consensus element recognized and cleaved by IRE1α

Daisuke Oikawa, Mio Tokuda, Akira Hosoda, Takao Iwawaki

Nucleic Acids Res. 2010 Oct; 38(18): 6265–6273. Published online 2010 May 27. doi: 10.1093/nar/gkq452

PMCID:: PMC2952871

Abstract Article PDF–9.1M

Select item 275392517.

Identification and characterization of the interferon-β-mediated p53 signal pathway in human peripheral blood mononuclear cells

Fanglin Zhang, Subramaniam Sriram

Immunology. 2009 Sep; 128(1 Pt 2): e905–e918. doi: 10.1111/j.1365-2567.2009.03104.x

PMCID:: PMC2753925

Abstract Article PDF–641K

Select item 271608518.

MicroRNA miR-196a-2 and breast cancer: a genetic and epigenetic association study and functional analysis

Aaron E. Hoffman, Tongzhang Zheng, Chunhui Yi, Derek Leaderer, Joanne Weidhaas, Frank Slack, Yawei Zhang, Trupti Paranjape, Yong Zhu

Cancer Res. Author manuscript; available in PMC 2010 Jul 15.

Published in final edited form as: Cancer Res. 2009 Jul 15; 69(14): 5970–5977. Published online 2009 Jun 30. doi: 10.1158/0008-5472.CAN-09-0236

Correction in:: volume 69 on page 6758

PMCID:: PMC2716085

Abstract Article PDF–985K

Select item 253118719.

Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males

Peter C Charles, Brian D Alder, Eleanor G Hilliard, Jonathan C Schisler, Robert E Lineberger, Joel S Parker, Sabeen Mapara, Samuel S Wu, Andrea Portbury, Cam Patterson, George A Stouffer

BMC Med Genomics. 2008; 1: 38. Published online 2008 Aug 18. doi: 10.1186/1755-8794-1-38