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Select item 66152321.

Rewiring E2F1 with classical NHEJ via APLF suppression promotes bladder cancer invasiveness

Christin Richter, Stephan Marquardt, Fanghua Li, Alf Spitschak, Nico Murr, Berdien A. H. Edelhäuser, George Iliakis, Brigitte M. Pützer, Stella Logotheti

J Exp Clin Cancer Res. 2019; 38: 292. Published online 2019 Jul 8. doi: 10.1186/s13046-019-1286-9

PMCID:: PMC6615232

Abstract Article PDF–2.1M

Select item 65886502.

E2F1 mediates the downregulation of POLD1 in replicative senescence

Shichao Gao, Qiao Song, Jing Liu, Xiaomin Zhang, Xunming Ji, Peichang Wang

Cell Mol Life Sci. 2019 Jul; 76(14): 2833–2850. Published online 2019 Mar 20. doi: 10.1007/s00018-019-03070-z

PMCID:: PMC6588650

Abstract Article PDF–4.9M

Select item 3605013.

Molecular cloning of cellular genes encoding retinoblastoma-associated proteins: identification of a gene with properties of the transcription factor E2F.

B Shan, X Zhu, P L Chen, T Durfee, Y Yang, D Sharp, W H Lee

Mol Cell Biol. 1992 Dec; 12(12): 5620–5631. doi: 10.1128/mcb.12.12.5620

PMCID:: PMC360501

Summary Page Browse PDF–2.9M

Select item 65799974.

TFAP2E methylation promotes 5-fluorouracil resistance via exosomal miR-106a-5p and miR-421 in gastric cancer MGC-803 cells

Sun Jingyue, Wang Xiao, Zha Juanmin, Li Wei, Li Daoming, Xu Hong

Mol Med Rep. 2019 Jul; 20(1): 323–331. Published online 2019 May 14. doi: 10.3892/mmr.2019.10237

PMCID:: PMC6579997

Abstract Article PDF–1.3M

Select item 64076155.

Non-overlapping Control of Transcriptome by Promoter- and Super-Enhancer-Associated Dependencies in Multiple Myeloma

Mariateresa Fulciniti, Charles Y. Lin, Mehmet K. Samur, Michael A. Lopez, Irtisha Singh, Matthew A. Lawlor, Raphael E. Szalat, Christopher J. Ott, Herve’ Avet-Loiseau, Kenneth C. Anderson, Richard A. Young, James E. Bradner, Nikhil C. Munshi

Cell Rep. Author manuscript; available in PMC 2019 Mar 8.

Published in final edited form as: Cell Rep. 2018 Dec 26; 25(13): 3693–3705.e6. doi: 10.1016/j.celrep.2018.12.016

PMCID:: PMC6407615

Abstract Article PDF–1.1M

Select item 64068126.

Pan-Cancer Analyses Reveal Genomic Features of FOXM1 Overexpression in Cancer

Carter J Barger, Connor Branick, Linda Chee, Adam R. Karpf

Cancers (Basel) 2019 Feb; 11(2): 251. Published online 2019 Feb 21. doi: 10.3390/cancers11020251

PMCID:: PMC6406812

Abstract Article PDF–2.1M

Select item 64059727.

MiR-1205 functions as a tumor suppressor by disconnecting the synergy between KRAS and MDM4/E2F1 in non-small cell lung cancer

Hong Yan, Xiaoying Chen, Yu Li, Lei Fan, Yusi Tai, Yang Zhou, Yuxiang Chen, Xinming Qi, Ruimin Huang, Jin Ren

Am J Cancer Res. 2019; 9(2): 312–329. Published online 2019 Feb 1.

PMCID:: PMC6405972

Abstract Article PDF–5.0M

Select item 63760048.

Autofluorescence is a Reliable in vitro Marker of Cellular Senescence in Human Mesenchymal Stromal Cells

Alessandro Bertolo, Martin Baur, Julien Guerrero, Tobias Pötzel, Jivko Stoyanov

Sci Rep. 2019; 9: 2074. Published online 2019 Feb 14. doi: 10.1038/s41598-019-38546-2

PMCID:: PMC6376004

Abstract Article PDF–3.9M

Select item 62202629.

CDC20B is required for deuterosome-mediated centriole production in multiciliated cells

Diego R. Revinski, Laure-Emmanuelle Zaragosi, Camille Boutin, Sandra Ruiz-Garcia, Marie Deprez, Virginie Thomé, Olivier Rosnet, Anne-Sophie Gay, Olivier Mercey, Agnès Paquet, Nicolas Pons, Gilles Ponzio, Brice Marcet, Laurent Kodjabachian, Pascal Barbry

Nat Commun. 2018; 9: 4668. Published online 2018 Nov 7. doi: 10.1038/s41467-018-06768-z

PMCID:: PMC6220262

Abstract Article PDF–6.6M

Select item 612139510.

The Role of the Nuclear Factor κB Pathway in the Cellular Response to Low and High Linear Energy Transfer Radiation

Christine E. Hellweg, Luis F. Spitta, Kristina Koch, Arif A. Chishti, Bernd Henschenmacher, Sebastian Diegeler, Bikash Konda, Sebastian Feles, Claudia Schmitz, Thomas Berger, Christa Baumstark-Khan

Int J Mol Sci. 2018 Aug; 19(8): 2220. Published online 2018 Jul 30. doi: 10.3390/ijms19082220

PMCID:: PMC6121395

Abstract Article PDF–7.3M

Select item 595881411.

Bacillus Calmette-Guérin induces rapid gene expression changes in human bladder cancer cell lines that may modulate its survival

Juwita N. Rahmat, Kesavan Esuvaranathan, Ratha Mahendran

Oncol Lett. 2018 Jun; 15(6): 9231–9241. Published online 2018 Apr 11. doi: 10.3892/ol.2018.8462

PMCID:: PMC5958814

Abstract Article PDF–1.0M

Select item 568505512.

Bevacizumab and gefitinib enhanced whole-brain radiation therapy for brain metastases due to non-small-cell lung cancer

R.F. Yang, B. Yu, R.Q. Zhang, X.H. Wang, C. Li, P. Wang, Y. Zhang, B. Han, X.X. Gao, L. Zhang, Z.M. Jiang

Braz J Med Biol Res. 2018; 51(1): e6073. Published online 2017 Nov 17. doi: 10.1590/1414-431X20176073

PMCID:: PMC5685055

Abstract Article PDF–619K

Select item 537356513.

Custom RT-qPCR-array for glaucoma filtering surgery prognosis

Iñaki Rodriguez-Agirretxe, Iker Garcia, Javier Soria, Tatiana Maria Suarez, Arantxa Acera

PLoS One. 2017; 12(3): e0174559. Published online 2017 Mar 30. doi: 10.1371/journal.pone.0174559

PMCID:: PMC5373565

Abstract Article PDF–2.2M

Select item 532508014.

Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins

Jonathan Choiniere, Jianguo Wu, Li Wang

Mol Pharmacol. 2017 Mar; 91(3): 189–196. Published online 2017 Mar. doi: 10.1124/mol.116.106757

PMCID:: PMC5325080

Abstract Article PDF–1.8M

Select item 521524115.

IL-15 enhances the antitumor effect of human antigen-specific CD8⁺ T cells by cellular senescence delay

Jinsheng Weng, Kelsey E. Moriarty, Flavio Egidio Baio, Fuliang Chu, Sung-Doo Kim, Jin He, Zuliang Jie, Xiaoping Xie, Wencai Ma, Jianfei Qian, Liang Zhang, Jing Yang, Qing Yi, Sattva S. Neelapu, Larry W. Kwak

Oncoimmunology. 2016; 5(12): e1237327. Published online 2016 Oct 7. doi: 10.1080/2162402X.2016.1237327

PMCID:: PMC5215241

Abstract Article PDF–1.1M

Select item 461514016.

Oxidized ATM promotes abnormal proliferation of breast CAFs through maintaining intracellular redox homeostasis and activating the PI3K-AKT, MEK-ERK, and Wnt-β-catenin signaling pathways

Shifu Tang, Yixuan Hou, Hailong Zhang, Gang Tu, Li Yang, Yifan Sun, Lei Lang, Xi Tang, Yan-e Du, Mingli Zhou, Tenghua Yu, Liyun Xu, Siyang Wen, Chunming Liu, Manran Liu

Cell Cycle. 2015 Jun 15; 14(12): 1908–1924. Published online 2015 May 13. doi: 10.1080/15384101.2015.1041685

PMCID:: PMC4615140

Abstract Article PDF–1.7M

Select item 457719717.

Epigenetic silencing of tumor suppressor genes during in vitro Epstein–Barr virus infection

Abhik Saha, Hem C. Jha, Santosh K. Upadhyay, Erle S. Robertson

Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37): E5199–E5207. Published online 2015 Aug 31. doi: 10.1073/pnas.1503806112

PMCID:: PMC4577197

Abstract Article PDF–2.0M

Select item 454201018.

Epigenetic regulation of apoptosis and cell cycle regulatory genes in human colon carcinoma cells

Amy V. Paschall, Kebin Liu

Genom Data. 2015 Sep; 5: 189–191. Published online 2015 Jun 12. doi: 10.1016/j.gdata.2015.05.043

PMCID:: PMC4542010

Abstract Article PDF–363K

Select item 451562819.

Molecular Mechanisms by Which a Fucus vesiculosus Extract Mediates Cell Cycle Inhibition and Cell Death in Pancreatic Cancer Cells

Ulf Geisen, Marion Zenthoefer, Matthias Peipp, Jannik Kerber, Johannes Plenge, Antonella Managò, Markus Fuhrmann, Roland Geyer, Steffen Hennig, Dieter Adam, Levent Piker, Gerald Rimbach, Holger Kalthoff

Mar Drugs. 2015 Jul; 13(7): 4470–4491. Published online 2015 Jul 20. doi: 10.3390/md13074470

PMCID:: PMC4515628

Abstract Article PDF–3.6M

Select item 450875020.

An R132H Mutation in Isocitrate Dehydrogenase 1 Enhances p21 Expression and Inhibits Phosphorylation of Retinoblastoma Protein in Glioma Cells

Satsuki Miyata, Masashi Urabe, Akira Gomi, Mutsumi Nagai, Takashi Yamaguchi, Tomonori Tsukahara, Hiroaki Mizukami, Akihiro Kume, Keiya Ozawa, Eiju Watanabe

Neurol Med Chir (Tokyo) 2013 Oct; 53(10): 645–654. Published online 2013 Oct 25. doi: 10.2176/nmc.oa2012-0409