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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 66455352.

Cullin-4B E3 ubiquitin ligase mediates Apaf-1 ubiquitination to regulate caspase-9 activity

Eri Ohta, Masanori Itoh, Masashi Ueda, Yoko Hida, Miao-xing Wang, Miki Hayakawa-Ogura, Shimo Li, Emika Nishida, Kazunori Ohta, Tana, Saiful Islam, Kiyomi Nakagawa, Tomomi Sunayama, Huayue Chen, So Hirata, Masashi Endo, Yoya Ohno, Toshiyuki Nakagawa

PLoS One. 2019; 14(7): e0219782. Published online 2019 Jul 22. doi: 10.1371/journal.pone.0219782

PMCID:: PMC6645535

Abstract Article PDF–2.9M

Select item 67804883.

Long Non-Coding RNAs Modulate Sjögren’s Syndrome Associated Gene Expression and Are Involved in the Pathogenesis of the Disease

Marzia Dolcino, Elisa Tinazzi, Claudio Vitali, Nicoletta Del Papa, Antonio Puccetti, Claudio Lunardi

J Clin Med. 2019 Sep; 8(9): 1349. Published online 2019 Sep 1. doi: 10.3390/jcm8091349

PMCID:: PMC6780488

Abstract Article PDF–3.6M

Select item 66594394.

European mtDNA Variants Are Associated With Differential Responses to Cisplatin, an Anticancer Drug: Implications for Drug Resistance and Side Effects

Tej H. Patel, Lucas Norman, Steven Chang, Sina Abedi, Catherine Liu, Marilyn Chwa, Shari R. Atilano, Kunal Thaker, Stephanie Lu, S. Michal Jazwinski, Michael V. Miceli, Nitin Udar, Daniela Bota, M. Cristina Kenney

Front Oncol. 2019; 9: 640. Published online 2019 Jul 19. doi: 10.3389/fonc.2019.00640

PMCID:: PMC6659439

Abstract Article PDF–1.8M

Select item 63911455.

The in vitro and in vivo anti-melanoma effects of hydroxyapatite nanoparticles: influences of material factors

Hongfeng Wu, Zhongtao Li, Jiaoqing Tang, Xiao Yang, Yong Zhou, Bo Guo, Lin Wang, Xiangdong Zhu, Chongqi Tu, Xingdong Zhang

Int J Nanomedicine. 2019; 14: 1177–1191. Published online 2019 Feb 15. doi: 10.2147/IJN.S184792

PMCID:: PMC6391145

Abstract Article PDF–4.5M

Select item 62740526.

Combinatorial Cytotoxic Effects of Damnacanthal and Doxorubicin against Human Breast Cancer MCF-7 Cells in Vitro

Muhammad Yusran Abdul Aziz, Nadiah Abu, Swee Keong Yeap, Wan Yong Ho, Abdul Rahman Omar, Nor Hadiani Ismail, Syahida Ahmad, Mehdi R. Pirozyan, Nadeem M. Akhtar, Noorjahan Banu Alitheen

Molecules. 2016 Sep; 21(9): 1228. Published online 2016 Sep 14. doi: 10.3390/molecules21091228

PMCID:: PMC6274052

Abstract Article PDF–2.8M

Select item 61213957.

The Role of the Nuclear Factor κB Pathway in the Cellular Response to Low and High Linear Energy Transfer Radiation

Christine E. Hellweg, Luis F. Spitta, Kristina Koch, Arif A. Chishti, Bernd Henschenmacher, Sebastian Diegeler, Bikash Konda, Sebastian Feles, Claudia Schmitz, Thomas Berger, Christa Baumstark-Khan

Int J Mol Sci. 2018 Aug; 19(8): 2220. Published online 2018 Jul 30. doi: 10.3390/ijms19082220

PMCID:: PMC6121395

Abstract Article PDF–7.3M

Select item 60179158.

Curcumin Analog DK1 Induces Apoptosis in Human Osteosarcoma Cells In Vitro through Mitochondria-Dependent Signaling Pathway

Muhammad Nazirul Mubin Aziz, Yazmin Hussin, Nurul Fattin Che Rahim, Noraini Nordin, Nurul Elyani Mohamad, Swee Keong Yeap, Chean Yeah Yong, Mas Jaffri Masarudin, Yoke Kqueen Cheah, Nadiah Abu, Muhammad Nadeem Akhtar, Noorjahan Banu Alitheen

Molecules. 2018 Jan; 23(1): 75. Published online 2018 Jan 5. doi: 10.3390/molecules23010075

PMCID:: PMC6017915

Abstract Article PDF–3.2M

Select item 59794159.

DK1 Induces Apoptosis via Mitochondria-Dependent Signaling Pathway in Human Colon Carcinoma Cell Lines In Vitro

Yazmin Hussin, Muhammad Nazirul Mubin Aziz, Nurul Fattin Che Rahim, Swee Keong Yeap, Nurul Elyani Mohamad, Mas Jaffri Masarudin, Noraini Nordin, Nik Mohd Afizan-Nik Abd Rahman, Chean Yeah Yong, Muhammad Nadeem Akhtar, Siti Noor Hajar Zamrus, Noorjahan Banu Alitheen

Int J Mol Sci. 2018 Apr; 19(4): 1151. Published online 2018 Apr 11. doi: 10.3390/ijms19041151

PMCID:: PMC5979415

Abstract Article PDF–2.3M

Select item 577520310.

Pseudoalteromonas haloplanktis TAC125 produces 4-hydroxybenzoic acid that induces pyroptosis in human A459 lung adenocarcinoma cells

Filomena Sannino, Clementina Sansone, Christian Galasso, Sara Kildgaard, Pietro Tedesco, Renato Fani, Gennaro Marino, Donatella de Pascale, Adrianna Ianora, Ermenegilda Parrilli, Thomas Ostenfeld Larsen, Giovanna Romano, Maria Luisa Tutino

Sci Rep. 2018; 8: 1190. Published online 2018 Jan 19. doi: 10.1038/s41598-018-19536-2

PMCID:: PMC5775203

Abstract Article PDF–1.2M

Select item 546672511.

Angiotensin II type 2 receptor promotes apoptosis and inhibits angiogenesis in bladder cancer

Nana Pei, Yingying Mao, Pengfei Wan, Xinglu Chen, Andrew Li, Huiying Chen, Jinlong Li, Renqiang Wan, Yanling Zhang, Hongyan Du, Baihong Chen, Guangyu Jiang, Minghan Xia, Colin Sumners, Guixue Hu, Dongsheng Gu, Hongwei Li

J Exp Clin Cancer Res. 2017; 36: 77. Published online 2017 Jun 9. doi: 10.1186/s13046-017-0542-0

PMCID:: PMC5466725

Abstract Article PDF–2.7M

Select item 536304112.

Involvement of apoptotic pathways in docosahexaenoic acid-induced benefit in prostate cancer: Pathway-focused gene expression analysis using RT² Profile PCR Array System

Yanan Sun, Xiaopeng Jia, Lianguo Hou, Xing Liu, Qiang Gao

Lipids Health Dis. 2017; 16: 59. Published online 2017 Mar 23. doi: 10.1186/s12944-017-0442-5

PMCID:: PMC5363041

Abstract Article PDF–1.2M

Select item 512576013.

Blockage of both the extrinsic and intrinsic pathways of diazinon-induced apoptosis in PaTu cells by magnesium oxide and selenium nanoparticles

Mahdi Shiri, Mona Navaei-Nigjeh, Maryam Baeeri, Mahban Rahimifard, Hossein Mahboudi, Ahmad Reza Shahverdi, Abbas Kebriaeezadeh, Mohammad Abdollahi

Int J Nanomedicine. 2016; 11: 6239–6250. Published online 2016 Nov 22. doi: 10.2147/IJN.S119680

PMCID:: PMC5125760

Abstract Article PDF–1.1M

Select item 481446514.

Dual Regulation of Cell Death and Cell Survival upon Induction of Cellular Stress by Isopimara-7,15-Dien-19-Oic Acid in Cervical Cancer, HeLa Cells In vitro

Nadiah Abu, Swee K. Yeap, Ahmad Z. Mat Pauzi, M. Nadeem Akhtar, Nur R. Zamberi, Jamil Ismail, Seema Zareen, Noorjahan B. Alitheen

Front Pharmacol. 2016; 7: 89. Published online 2016 Mar 31. doi: 10.3389/fphar.2016.00089

PMCID:: PMC4814465

Abstract Article PDF–2.0M

Select item 463564815.

Saturated fatty acids enhance TLR4 immune pathways in human trophoblasts

Xiaohua Yang, Maricela Haghiac, Patricia Glazebrook, Judi Minium, Patrick M. Catalano, Sylvie Hauguel-de Mouzon

Hum Reprod. 2015 Sep; 30(9): 2152–2159. Published online 2015 Jul 22. doi: 10.1093/humrep/dev173

PMCID:: PMC4635648

Abstract Article PDF–535K

Select item 452870016.

Mechanistic basis for protection of differentiated SH-SY5Y cells by oryzanol-rich fraction against hydrogen peroxide-induced neurotoxicity

Norsharina Ismail, Maznah Ismail, Mustapha Umar Imam, Nur Hanisah Azmi, Siti Farhana Fathy, Jhi Biau Foo, Muhammad Firdaus Abu Bakar

BMC Complement Altern Med. 2014; 14: 467. Published online 2014 Dec 5. doi: 10.1186/1472-6882-14-467

PMCID:: PMC4528700

Abstract Article PDF–1.4M

Select item 452224417.

Characterization of ex vivo cultured limbal, conjunctival, and oral mucosal cells: A comparative study with implications in transplantation medicine

Kamesh Dhamodaran, Murali Subramani, Nallathambi Jeyabalan, Murugeswari Ponnalagu, Priyanka Chevour, Reshma Shetty, Himanshu Matalia, Rohit Shetty, Sabina Evan Prince, Debashish Das

Mol Vis. 2015; 21: 828–845. Published online 2015 Jul 31.