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Items: 12

1.
Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations
Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu
Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3
PMCID:
PMC6742646
AbstractArticlePDF–1.2M
2.
AMP-activated protein kinase complexes containing the β2 regulatory subunit are up-regulated during and contribute to adipogenesis
Omar J. Katwan, Fatmah Alghamdi, Tarek A. Almabrouk, Sarah J. Mancini, Simon Kennedy, Jonathan S. Oakhill, John W. Scott, Ian P. Salt
Biochem J. 2019 Jun 28; 476(12): 1725–1740. Prepublished online 2019 Jun 12. Published online 2019 Jun 26. doi: 10.1042/BCJ20180714
PMCID:
PMC6595317
AbstractArticlePDF–4.4M
3.
AMPK signaling linked to the schizophrenia-associated 1q21.1 deletion is required for neuronal and sleep maintenance
Stanislav Nagy, Gianna W. Maurer, Julie L. Hentze, Morten Rose, Thomas M. Werge, Kim Rewitz
PLoS Genet. 2018 Dec; 14(12): e1007623. Published online 2018 Dec 19. doi: 10.1371/journal.pgen.1007623
PMCID:
PMC6317821
AbstractArticlePDF–3.0M
4.
Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK)
Xin Gu, Michael D. Bridges, Yan Yan, Parker W. de Waal, X. Edward Zhou, Kelly M. Suino-Powell, H. Eric Xu, Wayne L. Hubbell, Karsten Melcher
J Biol Chem. 2018 Nov 2; 293(44): 16994–17007. Published online 2018 Sep 11. doi: 10.1074/jbc.RA118.004101
PMCID:
PMC6222100
AbstractArticlePDF–1.7M
5.
Architecture of the human interactome defines protein communities and disease networks
Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper
Nature. Author manuscript; available in PMC 2017 Nov 17.
Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366
PMCID:
PMC5531611
AbstractArticlePDF–2.7M
6.
Dysregulation of sterol regulatory element-binding protein 2 gene in HIV treatment-experienced individuals
Anuoluwapo Sopeyin, Lei Zhou, Min Li, Lydia Barakat, Elijah Paintsil
PLoS One. 2019; 14(12): e0226573. Published online 2019 Dec 17. doi: 10.1371/journal.pone.0226573
PMCID:
PMC6917281
AbstractArticlePDF–1.1M
7.
Combined chemical genetics and data-driven bioinformatics approach identifies receptor tyrosine kinase inhibitors as host-directed antimicrobials
Cornelis J. Korbee, Matthias T. Heemskerk, Dragi Kocev, Elisabeth van Strijen, Omid Rabiee, Kees L. M. C. Franken, Louis Wilson, Nigel D. L. Savage, Sašo Džeroski, Mariëlle C. Haks, Tom H. M. Ottenhoff
Nat Commun. 2018; 9: 358. Published online 2018 Jan 24. doi: 10.1038/s41467-017-02777-6
PMCID:
PMC5783939
AbstractArticlePDF–1.0M
8.
Oxyphenisatin acetate (NSC 59687) triggers a cell starvation response leading to autophagy, mitochondrial dysfunction, and autocrine TNFα-mediated apoptosis
Bethanie L Morrison, Michael E Mullendore, Luke H Stockwin, Suzanne Borgel, Melinda G Hollingshead, Dianne L Newton
Cancer Med. 2013 Oct; 2(5): 687–700. Published online 2013 Jul 23. doi: 10.1002/cam4.107
PMCID:
PMC3892800
AbstractArticlePDF–1.6M
9.
Transcriptome-Wide Analysis of UTRs in Non-Small Cell Lung Cancer Reveals Cancer-Related Genes with SNV-Induced Changes on RNA Secondary Structure and miRNA Target Sites
Radhakrishnan Sabarinathan, Anne Wenzel, Peter Novotny, Xiaojia Tang, Krishna R. Kalari, Jan Gorodkin
PLoS One. 2014; 9(1): e82699. Published online 2014 Jan 8. doi: 10.1371/journal.pone.0082699
PMCID:
PMC3885406
AbstractArticlePDF–1.0M
10.
Phosphofructokinase deficiency impairs ATP generation, autophagy, and redox balance in rheumatoid arthritis T cells
Zhen Yang, Hiroshi Fujii, Shalini V. Mohan, Jorg J. Goronzy, Cornelia M. Weyand
J Exp Med. 2013 Sep 23; 210(10): 2119–2134. doi: 10.1084/jem.20130252
PMCID:
PMC3782046
AbstractArticlePDF–2.8M
11.
Ets-1 Regulates Energy Metabolism in Cancer Cells
Meghan L. Verschoor, Leigh A. Wilson, Chris P. Verschoor, Gurmit Singh
PLoS One. 2010; 5(10): e13565. Published online 2010 Oct 22. doi: 10.1371/journal.pone.0013565
PMCID:
PMC2962648
AbstractArticlePDF–524K
12.
CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells
Silvia Deaglio, Semra Aydin, Maurizia Mello Grand, Tiziana Vaisitti, Luciana Bergui, Giovanni D’Arena, Giovanna Chiorino, Fabio Malavasi
Mol Med. 2010 Mar-Apr; 16(3-4): 87–91. Published online 2009 Nov 28. doi: 10.2119/molmed.2009.00146
PMCID:
PMC2785473
AbstractArticlePDF–245K

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