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Select item 67426461.

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations

Robert Fragoza, Jishnu Das, Shayne D. Wierbowski, Jin Liang, Tina N. Tran, Siqi Liang, Juan F. Beltran, Christen A. Rivera-Erick, Kaixiong Ye, Ting-Yi Wang, Li Yao, Matthew Mort, Peter D. Stenson, David N. Cooper, Xiaomu Wei, Alon Keinan, John C. Schimenti, Andrew G. Clark, Haiyuan Yu

Nat Commun. 2019; 10: 4141. Published online 2019 Sep 12. doi: 10.1038/s41467-019-11959-3

PMCID:: PMC6742646

Abstract Article PDF–1.2M

Select item 64711442.

Baicalein Suppresses Stem Cell-Like Characteristics in Radio- and Chemoresistant MDA-MB-231 Human Breast Cancer Cells through Up-Regulation of IFIT2

So Yae Koh, Jeong Yong Moon, Tatsuya Unno, Somi Kim Cho

Nutrients. 2019 Mar; 11(3): 624. Published online 2019 Mar 14. doi: 10.3390/nu11030624

PMCID:: PMC6471144

Abstract Article PDF–5.4M

Select item 60073073.

IFIT3 and IFIT2/3 promote IFIT1-mediated translation inhibition by enhancing binding to non-self RNA

Renata C Fleith, Harriet V Mears, Xin Yun Leong, Thomas J Sanford, Edward Emmott, Stephen C Graham, Daniel S Mansur, Trevor R Sweeney

Nucleic Acids Res. 2018 Jun 1; 46(10): 5269–5285. Published online 2018 Mar 15. doi: 10.1093/nar/gky191

PMCID:: PMC6007307

Abstract Article PDF–3.7M

Select item 58337364.

PLZF inhibits proliferation and metastasis of gallbladder cancer by regulating IFIT2

Hui Shen, Ming Zhan, Yonglong Zhang, Shuai Huang, Sunwang Xu, Xince Huang, Min He, Yanhua Yao, Mohan Man, Jian Wang

Cell Death Dis. 2018 Feb; 9(2): 71. Published online 2018 Jan 22. doi: 10.1038/s41419-017-0107-3

PMCID:: PMC5833736

Abstract Article PDF–5.2M

Select item 55316115.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 67547856.

Structural Basis for Influenza Virus NS1 Protein Block of mRNA Nuclear Export

Ke Zhang, Yihu Xie, Raquel Muñoz-Moreno, Juan Wang, Liang Zhang, Matthew Esparza, Adolfo García-Sastre, Beatriz M.A. Fontoura, Yi Ren

Nat Microbiol. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Nat Microbiol. 2019 Oct; 4(10): 1671–1679. Published online 2019 Jul 1. doi: 10.1038/s41564-019-0482-x

PMCID:: PMC6754785

Abstract Article PDF–1.7M

Select item 67415387.

Interferon-Induced Proteins with Tetratricopeptide Repeats 1 and 2 Are Cellular Factors That Limit Hepatitis B Virus Replication

Rongjuan Pei, Bo Qin, Xiaoyong Zhang, Wandi Zhu, Thekla Kemper, Zhiyong Ma, Martin Trippler, Joerg Schlaak, Xinwen Chen, Mengji Lu

J Innate Immun. 2014 Feb; 6(2): 182–191. Published online 2013 Jul 18. doi: 10.1159/000353220

PMCID:: PMC6741538

Abstract Article PDF–326K

Select item 59418058.

Gene Expression Profiling in Behcet's Disease Indicates an Autoimmune Component in the Pathogenesis of the Disease and Opens New Avenues for Targeted Therapy

Antonio Puccetti, Piera Filomena Fiore, Andrea Pelosi, Elisa Tinazzi, Giuseppe Patuzzo, Giuseppe Argentino, Francesca Moretta, Claudio Lunardi, Marzia Dolcino

J Immunol Res. 2018; 2018: 4246965. Published online 2018 Apr 24. doi: 10.1155/2018/4246965

PMCID:: PMC5941805

Abstract Article PDF–3.6M

Select item 58573579.

Mitotic progression following DNA damage enables pattern recognition within micronuclei

Shane M Harding, Joseph L Benci, Jerome Irianto, Dennis E Discher, Andy J Minn, Roger A Greenberg

Nature. Author manuscript; available in PMC 2018 Mar 18.

Published in final edited form as: Nature. 2017 Aug 24; 548(7668): 466–470. Published online 2017 Jul 31. doi: 10.1038/nature23470

PMCID:: PMC5857357

Abstract Article PDF–3.2M

Select item 584858610.

Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome

Masood Abu-Halima, Mustafa Kahraman, Dominic Henn, Tanja Rädle-Hurst, Andreas Keller, Hashim Abdul-Khaliq, Eckart Meese

J Transl Med. 2018; 16: 60. Published online 2018 Mar 12. doi: 10.1186/s12967-018-1429-3

PMCID:: PMC5848586

Abstract Article PDF–1.0M

Select item 584572811.

Gene Profiling in Patients with Systemic Sclerosis Reveals the Presence of Oncogenic Gene Signatures

Marzia Dolcino, Andrea Pelosi, Piera Filomena Fiore, Giuseppe Patuzzo, Elisa Tinazzi, Claudio Lunardi, Antonio Puccetti

Front Immunol. 2018; 9: 449. Published online 2018 Mar 6. doi: 10.3389/fimmu.2018.00449

PMCID:: PMC5845728

Abstract Article PDF–3.0M

Select item 572501112.

Decreased expression of interferon-induced protein 2 (IFIT2) by Wnt/β-catenin signaling confers anti-apoptotic properties to colorectal cancer cells

Tomoyuki Ohsugi, Kiyoshi Yamaguchi, Chi Zhu, Tsuneo Ikenoue, Yoichi Furukawa

Oncotarget. 2017 Nov 21; 8(59): 100176–100186. Published online 2017 Oct 26. doi: 10.18632/oncotarget.22122

PMCID:: PMC5725011

Abstract Article PDF–1.9M

Select item 562551213.

Mechanism of Interferon-Stimulated Gene Induction in HIV-1-Infected Macrophages

Najla Nasr, Abdullateef A. Alshehri, Thomas K. Wright, Maryam Shahid, Bonnie M. Heiner, Andrew N. Harman, Rachel A. Botting, Karla J. Helbig, Michael R. Beard, Kazuo Suzuki, Anthony D. Kelleher, Paul Hertzog, Anthony L. Cunningham

J Virol. 2017 Oct 15; 91(20): e00744-17. Prepublished online 2017 Aug 2. Published online 2017 Sep 27. doi: 10.1128/JVI.00744-17

PMCID:: PMC5625512

Abstract Article PDF–2.4M

Select item 556722414.

DEMETER plant DNA demethylase induces antiviral response by interferon signalling in animal cells

Young Geun Mok, Ki Young Choi, Seung Hwan Hong, Jin Hoe Huh

Sci Rep. 2017; 7: 9160. Published online 2017 Aug 22. doi: 10.1038/s41598-017-08827-9

PMCID:: PMC5567224

Abstract Article PDF–2.5M

Select item 533132115.

Transcriptome Profiling of IL-17A Preactivated Mesenchymal Stem Cells: A Comparative Study to Unmodified and IFN-γ Modified Mesenchymal Stem Cells

Kisha Nandini Sivanathan, Darling Rojas-Canales, Shane T. Grey, Stan Gronthos, Patrick T. Coates

Stem Cells Int. 2017; 2017: 1025820. Published online 2017 Feb 15. doi: 10.1155/2017/1025820

PMCID:: PMC5331321

Abstract Article PDF–1.5M

Select item 530867516.

Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus

Eric Hastie, Marcela Cataldi, Megan J. Moerdyk, Sébastien A. Felt, Nury Steuerwald, Valery Z. Grdzelishvili

Oncotarget. 2016 Sep 20; 7(38): 61601–61618. Published online 2016 Aug 11. doi: 10.18632/oncotarget.11202

PMCID:: PMC5308675

Abstract Article PDF–4.5M

Select item 510113217.

Upregulation of Interferon-inducible and damage response pathways in chronic graft-versus-host disease

Frances T. Hakim, Sarfraz Memon, Ping Jin, Matin M. Imanguli, Huan Wang, Najibah Rehman, Xiao-Yi Yan, Jeremy Rose, Jacqueline W. Mays, Susan Dhamala, Veena Kapoor, William Telford, John Dickinson, Sean Davis, David Halverson, Haley B. Naik, Kristin Baird, Daniel Fowler, David Stroncek, Edward W. Cowen, Steven Z. Pavletic, Ronald E. Gress

J Immunol. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: J Immunol. 2016 Nov 1; 197(9): 3490–3503. Published online 2016 Sep 30. doi: 10.4049/jimmunol.1601054

PMCID:: PMC5101132

Abstract Article PDF–1.8M

Select item 504198218.

Small-molecule inhibition of STAT3 in radioresistant head and neck squamous cell carcinoma

Uddalak Bharadwaj, T. Kris Eckols, Xuejun Xu, Moses M. Kasembeli, Yunyun Chen, Makoto Adachi, Yongcheng Song, Qianxing Mo, Stephen Y. Lai, David J. Tweardy

Oncotarget. 2016 May 3; 7(18): 26307–26330. Published online 2016 Mar 25. doi: 10.18632/oncotarget.8368