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Select item 67560751.

Regulation of PERK expression by FOXO3: a vulnerability of drug-resistant cancer cells

Glowi Alasiri, Yannasittha Jiramongkol, Stefania Zona, Lavender Y. -N. Fan, Zimam Mahmud, Gyungyub Gong, Hee Jin Lee, Eric W. -F. Lam

Oncogene. 2019; 38(36): 6382–6398. Published online 2019 Jul 16. doi: 10.1038/s41388-019-0890-7

PMCID:: PMC6756075

Abstract Article PDF–3.4M

Select item 67518262.

Circ-Foxo3 is positively associated with the Foxo3 gene and leads to better prognosis of acute myeloid leukemia patients

Jiao Zhou, Ling-Yu Zhou, Xi Tang, Jing Zhang, Ling-Ling Zhai, Yun Yun Yi, Jing Yi, Jiang Lin, Jun Qian, Zhao-Qun Deng

BMC Cancer. 2019; 19: 930. Published online 2019 Sep 18. doi: 10.1186/s12885-019-5967-8

PMCID:: PMC6751826

Abstract Article PDF–1.2M

Select item 67289713.

Oncogenic Akt-FOXO3 loop favors tumor-promoting modes and enhances oxidative damage-associated hepatocellular carcinogenesis

Miao Lu, Daniel Hartmann, Rickmer Braren, Aayush Gupta, Baocai Wang, Yang Wang, Carolin Mogler, Zhangjun Cheng, Thomas Wirth, Helmut Friess, Jörg Kleeff, Norbert Hüser, Yoshiaki Sunami

BMC Cancer. 2019; 19: 887. Published online 2019 Sep 5. doi: 10.1186/s12885-019-6110-6

PMCID:: PMC6728971

Abstract Article PDF–8.1M

Select item 65822084.

Hippo kinases regulate cell junctions to inhibit tumor metastasis in response to oxidative stress

Yang Wang, Juan Li, Ya Gao, Yue Luo, Hong Luo, Liang Wang, Yong Yi, Zengqiang Yuan, Zhi-Xiong Jim Xiao

Redox Biol. 2019 Sep; 26: 101233. Published online 2019 Jun 4. doi: 10.1016/j.redox.2019.101233

PMCID:: PMC6582208

Abstract Article PDF–4.3M

Select item 65150045.

miR-590-3p Targets Cyclin G2 and FOXO3 to Promote Ovarian Cancer Cell Proliferation, Invasion, and Spheroid Formation

Mohamed Salem, Yanan Shan, Stefanie Bernaudo, Chun Peng

Int J Mol Sci. 2019 Apr; 20(8): 1810. Published online 2019 Apr 12. doi: 10.3390/ijms20081810

PMCID:: PMC6515004

Abstract Article PDF–3.5M

Select item 65949726.

LINC01355 suppresses breast cancer growth through FOXO3-mediated transcriptional repression of CCND1

Bolun Ai, Xiangyi Kong, Xiangyu Wang, Kai Zhang, Xue Yang, Jie Zhai, Ran Gao, Yihang Qi, Jing Wang, Zhongzhao Wang, Yi Fang

Cell Death Dis. 2019 Jul; 10(7): 502. Published online 2019 Jun 26. doi: 10.1038/s41419-019-1741-8

PMCID:: PMC6594972

Abstract Article PDF–2.0M

Select item 64326387.

The HDAC3-SMARCA4-miR27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma

Narendra Bharathy, Noah E. Berlow, Eric Wang, Jinu Abraham, Teagan P. Settelmeyer, Jody E. Hooper, Matthew N. Svalina, Yoshihiro Ishikawa, Keith Zientek, Zia Bajwa, Martin W. Goros, Brian S. Hernandez, Johannes E. Wolff, Michelle A. Rudek, Linping Xu, Nicole M. Anders, Ranadip Pal, Alexandria P. Harrold, Angela M. Davies, Arya Ashok, Darnell Bushby, Maria Mancini, Christopher Noakes, Neal C. Goodwin, Peter Ordentlich, James Keck, Douglas S. Hawkins, Erin R. Rudzinski, Bishwanath Chatterjee, Hans Peter Bächinger, Frederic G. Barr, Jennifer Liddle, Benjamin A. Garcia, Atiya Mansoor, Theodore J. Perkins, Christopher R. Vakoc, Joel E. Michalek, Charles Keller

Sci Signal. Author manuscript; available in PMC 2019 May 20.

Published in final edited form as: Sci Signal. 2018 Nov 20; 11(557): eaau7632. Published online 2018 Nov 20. doi: 10.1126/scisignal.aau7632

PMCID:: PMC6432638

Abstract Article PDF–2.2M

Select item 57599468.

Houttuynia cordata Thunb Promotes Activation of HIF-1A–FOXO3 and MEF2A Pathways to Induce Apoptosis in Human HepG2 Hepatocellular Carcinoma Cells

Jung Min Kim, In-Hu Hwang, Ik-Soon Jang, Min Kim, In Seok Bang, Soo Jung Park, Yun-Jo Chung, Jong-Cheon Joo, Min-Goo Lee

Integr Cancer Ther. 2017 Sep; 16(3): 360–372. Published online 2016 Oct 3. doi: 10.1177/1534735416670987

PMCID:: PMC5759946

Abstract Article PDF–1.1M

Select item 57273049.

Identification and characterization of two functional variants in the human longevity gene FOXO3

Friederike Flachsbart, Janina Dose, Liljana Gentschew, Claudia Geismann, Amke Caliebe, Carolin Knecht, Marianne Nygaard, Nandini Badarinarayan, Abdou ElSharawy, Sandra May, Anne Luzius, Guillermo G. Torres, Marlene Jentzsch, Michael Forster, Robert Häsler, Kathrin Pallauf, Wolfgang Lieb, Céline Derbois, Pilar Galan, Dmitriy Drichel, Alexander Arlt, Andreas Till, Ben Krause-Kyora, Gerald Rimbach, Hélène Blanché, Jean-François Deleuze, Lene Christiansen, Kaare Christensen, Michael Nothnagel, Philip Rosenstiel, Stefan Schreiber, Andre Franke, Susanne Sebens, Almut Nebel

Nat Commun. 2017; 8: 2063. Published online 2017 Dec 12. doi: 10.1038/s41467-017-02183-y

Correction in:: Nat Commun. 2018; 9: 320.

PMCID:: PMC5727304

Abstract Article PDF–832K

Select item 569782310.

Global transcriptome profile reveals abundance of DNA damage response and repair genes in individuals from high level natural radiation areas of Kerala coast

Vinay Jain, Birajalaxmi Das

PLoS One. 2017; 12(11): e0187274. Published online 2017 Nov 21. doi: 10.1371/journal.pone.0187274

PMCID:: PMC5697823

Abstract Article PDF–16M

Select item 569574511.

A Peroxidase Peroxiredoxin 1-Specific Redox Regulation of the Novel FOXO3 microRNA Target let-7

Barbara L. Hopkins, Monica Nadler, John J. Skoko, Thierry Bertomeu, Andrea Pelosi, Parisa Mousavi Shafaei, Kevin Levine, Anja Schempf, Bodvael Pennarun, Bo Yang, Dipak Datta, Octavian Bucur, Kenneth Ndebele, Steffi Oesterreich, Da Yang, Maria Giulia Rizzo, Roya Khosravi-Far, Carola A. Neumann

Antioxid Redox Signal. 2018 Jan 1; 28(1): 62–77. Published online 2018 Jan 1. doi: 10.1089/ars.2016.6871

PMCID:: PMC5695745

Abstract Article PDF–1.2M

Select item 556179312.

Gene expression profiling of human blastocysts from in vivo and ‘rescue IVM’ with or without melatonin treatment

Yan Hao, Zhiguo Zhang, Dan Han, Yunxia Cao, Ping Zhou, Zhaolian Wei, Mingrong Lv, Dawei Chen

Mol Med Rep. 2017 Aug; 16(2): 1278–1288. Published online 2017 Jun 9. doi: 10.3892/mmr.2017.6742

PMCID:: PMC5561793

Abstract Article PDF–963K

Select item 538180113.

IL-15 regulates migration, invasion, angiogenesis and genes associated with lipid metabolism and inflammation in prostate cancer

Krizia Rohena-Rivera, María M. Sánchez-Vázquez, Diana A. Aponte-Colón, Ingrid S. Forestier-Román, Mario E. Quintero-Aguiló, Magaly Martínez-Ferrer

PLoS One. 2017; 12(4): e0172786. Published online 2017 Apr 5. doi: 10.1371/journal.pone.0172786

PMCID:: PMC5381801

Abstract Article PDF–6.7M

Select item 532579014.

Impact of Hot and Cold Exposure on Human Skeletal Muscle Gene Expression

Roksana B. Zak, Robert J. Shute, Matthew W.S. Heesch, D. Taylor La Salle, Matthew P. Bubak, Nicholas E. Dinan, Terence L. Laursen, Dustin R. Slivka

Appl Physiol Nutr Metab. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Appl Physiol Nutr Metab. 2017 Mar; 42(3): 319–325. Published online 2016 Dec 1. doi: 10.1139/apnm-2016-0415

PMCID:: PMC5325790

Abstract Article PDF–687K

Select item 490848515.

Effect of dietary n‐3 PUFA supplementation on the muscle transcriptome in older adults

Jun Yoshino, Gordon I. Smith, Shannon C. Kelly, Sophie Julliand, Dominic N. Reeds, Bettina Mittendorfer

Physiol Rep. 2016 Jun; 4(11): e12785. Published online 2016 Jun 1. doi: 10.14814/phy2.12785

PMCID:: PMC4908485

Abstract Article PDF–172K

Select item 487709316.

IL-4 Causes Hyperpermeability of Vascular Endothelial Cells through Wnt5A Signaling

Tom Skaria, Julia Burgener, Esther Bachli, Gabriele Schoedon

PLoS One. 2016; 11(5): e0156002. Published online 2016 May 23. doi: 10.1371/journal.pone.0156002

PMCID:: PMC4877093

Abstract Article PDF–15M

Select item 460049317.

Looking for Pyroptosis-Modulating miRNAs as a Therapeutic Target for Improving Myocardium Survival

Seahyoung Lee, Eunhyun Choi, Min-Ji Cha, Ki-Chul Hwang

Mediators Inflamm. 2015; 2015: 254871. Published online 2015 Sep 27. doi: 10.1155/2015/254871

PMCID:: PMC4600493

Abstract Article PDF–535K

Select item 454723318.

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

Haiquan Lu, Debangshu Samanta, Lisha Xiang, Huimin Zhang, Hongxia Hu, Ivan Chen, John W. Bullen, Gregg L. Semenza

Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33): E4600–E4609. Published online 2015 Jul 30. doi: 10.1073/pnas.1513433112

PMCID:: PMC4547233

Abstract Article PDF–1.6M

Select item 410894619.

Reprogramming ovarian and breast cancer cells into non-cancerous cells by low-dose metformin or SN-38 through FOXO3 activation

Theodore Hu, Young Min Chung, Michelle Guan, Michael Ma, Jessica Ma, Jonathan S. Berek, Mickey C-T. Hu

Sci Rep. 2014; 4: 5810. Published online 2014 Jul 24. doi: 10.1038/srep05810

PMCID:: PMC4108946

Abstract Article PDF–3.5M

Select item 390770720.

Ageing has no effect on the regulation of the ubiquitin proteasome-related genes and proteins following resistance exercise

Renae J. Stefanetti, Evelyn Zacharewicz, Paul Della Gatta, Andrew Garnham, Aaron P. Russell, Séverine Lamon

Front Physiol. 2014; 5: 30. Published online 2014 Jan 31. doi: 10.3389/fphys.2014.00030

PMCID:: PMC3907707

Abstract Article PDF–1.3M

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