PMC Links for Nucleotide (Select 1519243160) - PMC

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Items: 13

Select item 58695871.

Extensive molecular tinkering in the evolution of the membrane attachment mode of the Rheb GTPase

Kristína Záhonová, Romana Petrželková, Matus Valach, Euki Yazaki, Denis V. Tikhonenkov, Anzhelika Butenko, Jan Janouškovec, Štěpánka Hrdá, Vladimír Klimeš, Gertraud Burger, Yuji Inagaki, Patrick J. Keeling, Vladimír Hampl, Pavel Flegontov, Vyacheslav Yurchenko, Marek Eliáš

Sci Rep. 2018; 8: 5239. Published online 2018 Mar 27. doi: 10.1038/s41598-018-23575-0

PMCID:: PMC5869587

Abstract Article PDF–3.8M

Select item 57635822.

An oncogenic mutant of RHEB, RHEB Y35N, exhibits an altered interaction with BRAF resulting in cancer transformation

Jeffrey J. Heard, Ivy Phung, Mark I. Potes, Fuyuhiko Tamanoi

BMC Cancer. 2018; 18: 69. Published online 2018 Jan 10. doi: 10.1186/s12885-017-3938-5

PMCID:: PMC5763582

Abstract Article PDF–1.3M

Select item 57500763.

Structural Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40

Haijuan Yang, Xiaolu Jiang, Buren Li, Hyo J. Yang, Meredith Miller, Angela Yang, Ankita Dhar, Nikola P. Pavletich

Nature. Author manuscript; available in PMC 2018 Jun 13.

Published in final edited form as: Nature. 2017 Dec 21; 552(7685): 368–373. Published online 2017 Dec 13. doi: 10.1038/nature25023

PMCID:: PMC5750076

Abstract Article PDF–3.0M

Select item 2318184.

Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals.

W M Yee, P F Worley

Mol Cell Biol. 1997 Feb; 17(2): 921–933. doi: 10.1128/mcb.17.2.921

PMCID:: PMC231818

Summary PDF–787K

Select item 68513935.

Dissecting the genetic basis of focal cortical dysplasia: a large cohort study

Sara Baldassari, Théo Ribierre, Elise Marsan, Homa Adle-Biassette, Sarah Ferrand-Sorbets, Christine Bulteau, Nathalie Dorison, Martine Fohlen, Marc Polivka, Sarah Weckhuysen, Georg Dorfmüller, Mathilde Chipaux, Stéphanie Baulac

Acta Neuropathol. 2019; 138(6): 885–900. Published online 2019 Aug 23. doi: 10.1007/s00401-019-02061-5

PMCID:: PMC6851393

Abstract Article PDF–2.6M

Select item 68027366.

A brain somatic RHEB doublet mutation causes focal cortical dysplasia type II

Shanshan Zhao, Zhenghui Li, Muxian Zhang, Lingliang Zhang, Honghua Zheng, Jinhuan Ning, Yanyan Wang, Fengpeng Wang, Xiaobin Zhang, Hexia Gan, Yuanqing Wang, Xian Zhang, Hong Luo, Guojun Bu, Huaxi Xu, Yi Yao, Yun-wu Zhang

Exp Mol Med. 2019 Jul; 51(7): 84. Published online 2019 Jul 23. doi: 10.1038/s12276-019-0277-4

PMCID:: PMC6802736

Abstract Article PDF–1.6M

Select item 56487727.

Variation in a range of mTOR-related genes associates with intracranial volume and intellectual disability

M. R. F. Reijnders, M. Kousi, G. M. van Woerden, M. Klein, J. Bralten, G. M. S. Mancini, T. van Essen, M. Proietti-Onori, E. E. J. Smeets, M. van Gastel, A. P. A. Stegmann, S. J. C. Stevens, S. H. Lelieveld, C. Gilissen, R. Pfundt, P. L. Tan, T. Kleefstra, B. Franke, Y. Elgersma, N. Katsanis, H. G. Brunner

Nat Commun. 2017; 8: 1052. Published online 2017 Oct 20. doi: 10.1038/s41467-017-00933-6

PMCID:: PMC5648772

Abstract Article PDF–1.3M

Select item 45804118.

G9a Inhibition Induces Autophagic Cell Death via AMPK/mTOR Pathway in Bladder Transitional Cell Carcinoma

Feng Li, Jin Zeng, Yang Gao, Zhenfeng Guan, Zhenkun Ma, Qi Shi, Chong Du, Jing Jia, Shan Xu, Xinyang Wang, Luke Chang, Dalin He, Peng Guo

PLoS One. 2015; 10(9): e0138390. Published online 2015 Sep 23. doi: 10.1371/journal.pone.0138390

PMCID:: PMC4580411

Abstract Article PDF–9.7M

Select item 38854069.

Transcriptome-Wide Analysis of UTRs in Non-Small Cell Lung Cancer Reveals Cancer-Related Genes with SNV-Induced Changes on RNA Secondary Structure and miRNA Target Sites

Radhakrishnan Sabarinathan, Anne Wenzel, Peter Novotny, Xiaojia Tang, Krishna R. Kalari, Jan Gorodkin

PLoS One. 2014; 9(1): e82699. Published online 2014 Jan 8. doi: 10.1371/journal.pone.0082699

PMCID:: PMC3885406

Abstract Article PDF–1.0M

Select item 284057010.

Screening of potential molecular targets for colorectal cancer therapy

Kimi Honma, Ichiro Takemasa, Ryo Matoba, Yusuke Yamamoto, Fumitaka Takeshita, Masaki Mori, Morito Monden, Kenichi Matsubara, Takahiro Ochiya

Int J Gen Med. 2009; 2: 243–257. Published online 2009 Dec 29. doi: 10.2147/ijgm.s5158

PMCID:: PMC2840570

Abstract Article PDF–1.2M

Select item 275392511.

Identification and characterization of the interferon-β-mediated p53 signal pathway in human peripheral blood mononuclear cells

Fanglin Zhang, Subramaniam Sriram

Immunology. 2009 Sep; 128(1 Pt 2): e905–e918. doi: 10.1111/j.1365-2567.2009.03104.x

PMCID:: PMC2753925

Abstract Article PDF–641K

Select item 269863712.

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis

Micah J. Drummond, Mitsunori Miyazaki, Hans C. Dreyer, Bart Pennings, Shaheen Dhanani, Elena Volpi, Karyn A. Esser, Blake B. Rasmussen

J Appl Physiol (1985) 2009 Apr; 106(4): 1403–1411. Published online 2008 Sep 11. doi: 10.1152/japplphysiol.90842.2008

PMCID:: PMC2698637

Abstract Article

Select item 127561313.

Linkage and Association Studies Identify a Novel Locus for Alzheimer Disease at 7q36 in a Dutch Population-Based Sample

Rosa Rademakers, Marc Cruts, Kristel Sleegers, Bart Dermaut, Jessie Theuns, Yurii Aulchenko, Stefan Weckx, Tim De Pooter, Marleen Van den Broeck, Ellen Corsmit, Peter De Rijk, Jurgen Del-Favero, John van Swieten, Cornelia M. van Duijn, Christine Van Broeckhoven

Am J Hum Genet. 2005 Oct; 77(4): 643–652. Published online 2005 Aug 30. doi: 10.1086/491749