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Select item 68881431.

Suz12 inactivation cooperates with JAK3 mutant signaling in the development of T-cell acute lymphoblastic leukemia

Michael Broux, Cristina Prieto, Sofie Demeyer, Marlies Vanden Bempt, Llucia Alberti-Servera, Inge Lodewijckx, Roel Vandepoel, Nicole Mentens, Olga Gielen, Kris Jacobs, Ellen Geerdens, Carmen Vicente, Charles E. de Bock, Jan Cools

Blood. 2019 Oct 17; 134(16): 1323–1336. Prepublished online 2019 Sep 6. doi: 10.1182/blood.2019000015

PMCID:: PMC6888143

Abstract Article

Select item 65919222.

Ubiquitin-specific protease 3 promotes cell migration and invasion by interacting with and deubiquitinating SUZ12 in gastric cancer

Xiaosheng Wu, Mengwei Liu, Huiqiong Zhu, Jing Wang, Weiyu Dai, Jiaying Li, Danping Zhu, Weimei Tang, Yizhi Xiao, Jianjiao Lin, Wenjing Zhang, Yong Sun, Yi Zhang, Yaying Chen, Guoxin Li, Aimin Li, Li Xiang, Side Liu, Jide Wang

J Exp Clin Cancer Res. 2019; 38: 277. Published online 2019 Jun 24. doi: 10.1186/s13046-019-1270-4

PMCID:: PMC6591922

Abstract Article PDF–13M

Select item 65490873.

miR-767-5p inhibits glioma proliferation and metastasis by targeting SUZ12

Jiale Zhang, Shuo Xu, Jia Xu, Yangyang Li, Jie Zhang, Jian Zhang, Xiaoming Lu

Oncol Rep. 2019 Jul; 42(1): 55–66. Published online 2019 May 13. doi: 10.3892/or.2019.7156

PMCID:: PMC6549087

Abstract Article PDF–2.6M

Select item 1874794.

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

Andrei Kuzmichev, Kenichi Nishioka, Hediye Erdjument-Bromage, Paul Tempst, Danny Reinberg

Genes Dev. 2002 Nov 15; 16(22): 2893–2905. doi: 10.1101/gad.1035902

PMCID:: PMC187479

Abstract Article PDF–571K

Select item 998595.

Use of Chromatin Immunoprecipitation To Clone Novel E2F Target Promoters

Amy S. Weinmann, Stephanie M. Bartley, Theresa Zhang, Michael Q. Zhang, Peggy J. Farnham

Mol Cell Biol. 2001 Oct; 21(20): 6820–6832. doi: 10.1128/MCB.21.20.6820-6832.2001

PMCID:: PMC99859

Abstract Article PDF–356K

Select item 334716.

Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors

Jason I. Koontz, A. Lee Soreng, Marisa Nucci, Frank C. Kuo, Patrick Pauwels, Herman van den Berghe, Paola Dal Cin, Jonathan A. Fletcher, Jeffrey Sklar

Proc Natl Acad Sci U S A. 2001 May 22; 98(11): 6348–6353. doi: 10.1073/pnas.101132598

PMCID:: PMC33471

Abstract Article PDF–675K

Select item 61202167.

High-throughput screening with nucleosome substrate identifies small-molecule inhibitors of the human histone lysine methyltransferase NSD2

Nathan P. Coussens, Stephen C. Kales, Mark J. Henderson, Olivia W. Lee, Kurumi Y. Horiuchi, Yuren Wang, Qing Chen, Ekaterina Kuznetsova, Jianghong Wu, Sirisha Chakka, Dorian M. Cheff, Ken Chih-Chien Cheng, Paul Shinn, Kyle R. Brimacombe, Min Shen, Anton Simeonov, Madhu Lal-Nag, Haiching Ma, Ajit Jadhav, Matthew D. Hall

J Biol Chem. 2018 Aug 31; 293(35): 13750–13765. Published online 2018 Jun 26. doi: 10.1074/jbc.RA118.004274

PMCID:: PMC6120216

Abstract Article PDF–3.9M

Select item 57888698.

Polycomb group protein Suz12 is regulated by a novel miRNA-like small RNA

Patrice Penfornis, Joseph D. Fernandes, Radhika R. Pochampally

Sci Rep. 2018; 8: 1720. Published online 2018 Jan 29. doi: 10.1038/s41598-018-19989-5

PMCID:: PMC5788869

Abstract Article PDF–2.9M

Select item 57071859.

Detection of Mutations in Myeloid Malignancies through Paired-Sample Analysis of Microdroplet-PCR Deep Sequencing Data

Donavan T. Cheng, Janice Cheng, Talia N. Mitchell, Aijazuddin Syed, Ahmet Zehir, Nana Yaa T. Mensah, Alifya Oultache, Khedoudja Nafa, Ross L. Levine, Maria E. Arcila, Michael F. Berger, Cyrus V. Hedvat

J Mol Diagn. 2014 Sep; 16(5): 504–518. doi: 10.1016/j.jmoldx.2014.05.006

PMCID:: PMC5707185

Abstract Article PDF–1.3M

Select item 562027710.

The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells

Evelina Miele, Sergio Valente, Vincenzo Alfano, Marianna Silvano, Paolo Mellini, Diana Borovika, Biagina Marrocco, Agnese Po, Zein Mersini Besharat, Giuseppina Catanzaro, Giuseppe Battaglia, Luana Abballe, Clemens Zwergel, Giulia Stazi, Ciro Milite, Sabrina Castellano, Marco Tafani, Peteris Trapencieris, Antonello Mai, Elisabetta Ferretti

Oncotarget. 2017 Sep 15; 8(40): 68557–68570. Published online 2017 Aug 2. doi: 10.18632/oncotarget.19782

PMCID:: PMC5620277

Abstract Article PDF–2.9M

Select item 415875911.

Interactive transcriptome analysis of malaria patients and infecting Plasmodium falciparum

Junya Yamagishi, Anna Natori, Mohammed E.M. Tolba, Arthur E. Mongan, Chihiro Sugimoto, Toshiaki Katayama, Shuichi Kawashima, Wojciech Makalowski, Ryuichiro Maeda, Yuki Eshita, Josef Tuda, Yutaka Suzuki

Genome Res. 2014 Sep; 24(9): 1433–1444. doi: 10.1101/gr.158980.113

Correction in:: Genome Res. 2018 Aug; 28(8): 1253.

PMCID:: PMC4158759

Abstract Article PDF–2.1M

Select item 388540612.

Transcriptome-Wide Analysis of UTRs in Non-Small Cell Lung Cancer Reveals Cancer-Related Genes with SNV-Induced Changes on RNA Secondary Structure and miRNA Target Sites

Radhakrishnan Sabarinathan, Anne Wenzel, Peter Novotny, Xiaojia Tang, Krishna R. Kalari, Jan Gorodkin

PLoS One. 2014; 9(1): e82699. Published online 2014 Jan 8. doi: 10.1371/journal.pone.0082699

PMCID:: PMC3885406

Abstract Article PDF–1.0M

Select item 365662713.

Assay Development for Histone Methyltransferases

Kurumi Y. Horiuchi, Mia M. Eason, Joseph J. Ferry, Jamie L. Planck, Colin P. Walsh, Robert F. Smith, Konrad T. Howitz, Haiching Ma

Assay Drug Dev Technol. 2013 May; 11(4): 227–236. doi: 10.1089/adt.2012.480

PMCID:: PMC3656627

Abstract Article PDF–510K

Select item 341250214.

Absence of the JAZF1/SUZ12 chimeric transcript in the immortalized non-neoplastic endometrial stromal cell line T HESCs

IOANNIS PANAGOPOULOS

Oncol Lett. 2010 Nov; 1(6): 947–950. Published online 2010 Sep 23. doi: 10.3892/ol.2010.185

PMCID:: PMC3412502

Abstract Article PDF–498K

Select item 302298515.

Identification of Genes Potentially Involved in the Increased Risk of Malignancy in NF1-Microdeleted Patients

Eric Pasmant, Julien Masliah-Planchon, Pascale Lévy, Ingrid Laurendeau, Nicolas Ortonne, Béatrice Parfait, Laurence Valeyrie-Allanore, Karen Leroy, Pierre Wolkenstein, Michel Vidaud, Dominique Vidaud, Ivan Bièche

Mol Med. 2011 Jan-Feb; 17(1-2): 79–87. Published online 2010 Sep 10. doi: 10.2119/molmed.2010.00079

PMCID:: PMC3022985

Abstract Article PDF–1.8M

Select item 300029716.

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

Christopher J. Sneeringer, Margaret Porter Scott, Kevin W. Kuntz, Sarah K. Knutson, Roy M. Pollock, Victoria M. Richon, Robert A. Copeland

Proc Natl Acad Sci U S A. 2010 Dec 7; 107(49): 20980–20985. Published online 2010 Nov 15. doi: 10.1073/pnas.1012525107

PMCID:: PMC3000297

Abstract Article PDF–548K

Select item 296661717.

miR-489 is a tumour-suppressive miRNA target PTPN11 in hypopharyngeal squamous cell carcinoma (HSCC)

N Kikkawa, T Hanazawa, L Fujimura, N Nohata, H Suzuki, H Chazono, D Sakurai, S Horiguchi, Y Okamoto, N Seki

Br J Cancer. 2010 Sep 7; 103(6): 877–884. Published online 2010 Aug 10. doi: 10.1038/sj.bjc.6605811

PMCID:: PMC2966617

Abstract Article PDF–464K

Select item 278547318.

CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells

Silvia Deaglio, Semra Aydin, Maurizia Mello Grand, Tiziana Vaisitti, Luciana Bergui, Giovanni D’Arena, Giovanna Chiorino, Fabio Malavasi

Mol Med. 2010 Mar-Apr; 16(3-4): 87–91. Published online 2009 Nov 28. doi: 10.2119/molmed.2009.00146

PMCID:: PMC2785473

Abstract Article PDF–245K

Select item 276575019.

Detection and Characterization of NF1 Microdeletions by Custom High Resolution Array CGH

Eric Pasmant, Audrey Sabbagh, Julien Masliah-Planchon, Véronique Haddad, Marie-José Hamel, Ingrid Laurendeau, Jean Soulier, Béatrice Parfait, Pierre Wolkenstein, Ivan Bièche, Michel Vidaud, Dominique Vidaud

J Mol Diagn. 2009 Nov; 11(6): 524–529. doi: 10.2353/jmoldx.2009.090064

PMCID:: PMC2765750

Abstract Article PDF–364K

Select item 227635420.

Type 2 NF1 Deletions Are Highly Unusual by Virtue of the Absence of Nonallelic Homologous Recombination Hotspots and an Apparent Preference for Female Mitotic Recombination

Katharina Steinmann, David N. Cooper, Lan Kluwe, Nadia A. Chuzhanova, Cornelia Senger, Eduard Serra, Conxi Lazaro, Montserrat Gilaberte, Katharina Wimmer, Viktor-Felix Mautner, Hildegard Kehrer-Sawatzki

Am J Hum Genet. 2007 Dec; 81(6): 1201–1220. Published online 2007 Oct 31. doi: 10.1086/522089

PMCID:: PMC2276354

Abstract Article PDF–683K

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