PMC Links for Nucleotide (Select 1519241776) - PMC

Select item 64420341.

The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A

Pilar Rivero-Ríos, María Romo-Lozano, Jesús Madero-Pérez, Andrew P. Thomas, Alice Biosa, Elisa Greggio, Sabine Hilfiker

J Biol Chem. 2019 Mar 29; 294(13): 4738–4758. Published online 2019 Feb 1. doi: 10.1074/jbc.RA118.005008

PMCID:: PMC6442034

Abstract Article PDF–6.5M

Select item 62958922.

Human MICAL1: Activation by the small GTPase Rab8 and small‐angle X‐ray scattering studies on the oligomerization state of MICAL1 and its complex with Rab8

Alessandro Esposito, Valeria Ventura, Maxim V. Petoukhov, Amrita Rai, Dmitri I. Svergun, Maria A. Vanoni

Protein Sci. 2019 Jan; 28(1): 150–166. Published online 2018 Oct 31. doi: 10.1002/pro.3512

PMCID:: PMC6295892

Abstract Article PDF–2.5M

Select item 62516823.

Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function

Myung Jong Kim, Sohee Jeon, Lena F Burbulla, Dimitri Krainc

Hum Mol Genet. 2018 Jun 1; 27(11): 1972–1988. Published online 2018 Mar 22. doi: 10.1093/hmg/ddy105

PMCID:: PMC6251682

Abstract Article PDF–1.1M

Select item 58284824.

LRRK2 mediated Rab8a phosphorylation promotes lipid storage

Miao Yu, Muhammad Arshad, Wenmin Wang, Dongyu Zhao, Li Xu, Linkang Zhou

Lipids Health Dis. 2018; 17: 34. Published online 2018 Feb 27. doi: 10.1186/s12944-018-0684-x

PMCID:: PMC5828482

Abstract Article PDF–1.4M

Select item 57788125.

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

Jesús Madero-Pérez, Elena Fdez, Belén Fernández, Antonio J. Lara Ordóñez, Marian Blanca Ramírez, Patricia Gómez-Suaga, Dieter Waschbüsch, Evy Lobbestael, Veerle Baekelandt, Angus C. Nairn, Javier Ruiz-Martínez, Ana Aiastui, Adolfo López de Munain, Pawel Lis, Thomas Comptdaer, Jean-Marc Taymans, Marie-Christine Chartier-Harlin, Alexandria Beilina, Adriano Gonnelli, Mark R. Cookson, Elisa Greggio, Sabine Hilfiker

Mol Neurodegener. 2018; 13: 3. Published online 2018 Jan 23. doi: 10.1186/s13024-018-0235-y

PMCID:: PMC5778812

Abstract Article PDF–12M

Select item 21198936.

A small rab GTPase is distributed in cytoplasmic vesicles in non polarized cells but colocalizes with the tight junction marker ZO-1 in polarized epithelial cells

J Cell Biol. 1994 Jan 1; 124(1): 101–115. doi: 10.1083/jcb.124.1.101

PMCID:: PMC2119893

Summary PDF–6.6M

Select item 59775217.

Identification and Characterization of Nine Novel Human Small GTPases Showing Variable Expressions in Liver Cancer Tissues

Hua He, Fangyan Dai, Long Yu, Xingyu She, Yong Zhao, Jianmin Jiang, Xiaosong Chen, Shouyuan Zhao

Gene Expr. 2002; 10(5-6): 231–242. Published online 2018 May 31. doi: 10.3727/000000002783992406

PMCID:: PMC5977521

Abstract Article PDF–1.3M

Select item 59150268.

TGFB1 is secreted through an unconventional pathway dependent on the autophagic machinery and cytoskeletal regulators

Julian Nüchel, Sushmita Ghatak, Alexandra V. Zuk, Anja Illerhaus, Matthias Mörgelin, Katrin Schönborn, Katrin Blumbach, Sara A. Wickström, Thomas Krieg, Gerhard Sengle, Markus Plomann, Beate Eckes

Autophagy. 2018; 14(3): 465–486. Published online 2018 Mar 11. doi: 10.1080/15548627.2017.1422850

PMCID:: PMC5915026

Abstract Article PDF–2.2M

Select item 57601009.

Loss-of-function of the ciliopathy protein Cc2d2a disorganizes the vesicle fusion machinery at the periciliary membrane and indirectly affects Rab8-trafficking in zebrafish photoreceptors

Irene Ojeda Naharros, Matthias Gesemann, José M. Mateos, Gery Barmettler, Austin Forbes, Urs Ziegler, Stephan C. F. Neuhauss, Ruxandra Bachmann-Gagescu

PLoS Genet. 2017 Dec; 13(12): e1007150. Published online 2017 Dec 27. doi: 10.1371/journal.pgen.1007150

PMCID:: PMC5760100

Abstract Article PDF–58M

Select item 288187410.

Trafficking of Sendai Virus Nucleocapsids Is Mediated by Intracellular Vesicles

Raychel Chambers, Toru Takimoto

PLoS One. 2010; 5(6): e10994. Published online 2010 Jun 7. doi: 10.1371/journal.pone.0010994

PMCID:: PMC2881874

Abstract Article PDF–1.7M

Select item 286657511.

Genome-wide changes accompanying the knockdown of Ep-CAM in retinoblastoma

Moutushy Mitra, Mallikarjuna Kandalam, Rama Shanker Verma, Krishnan UmaMaheswari, Subramanian Krishnakumar

Mol Vis. 2010; 16: 828–842. Published online 2010 May 11.

PMCID:: PMC2866575

Abstract Article PDF–2.6M

Select item 278547312.

CD38/CD31 interactions activate genetic pathways leading to proliferation and migration in chronic lymphocytic leukemia cells

Silvia Deaglio, Semra Aydin, Maurizia Mello Grand, Tiziana Vaisitti, Luciana Bergui, Giovanni D’Arena, Giovanna Chiorino, Fabio Malavasi

Mol Med. 2010 Mar-Apr; 16(3-4): 87–91. Published online 2009 Nov 28. doi: 10.2119/molmed.2009.00146

PMCID:: PMC2785473

Abstract Article PDF–245K

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