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Items: 1 to 20 of 53

1.
Loss of PDK4 switches the hepatic NF-κB/TNF pathway from pro-survival to pro-apoptosis
Jianguo Wu, Yulan Zhao, Young-Ki Park, Ji-Young Lee, Ling Gao, Jiajun Zhao, Li Wang
Hepatology. Author manuscript; available in PMC 2019 Sep 30.
Published in final edited form as: Hepatology. 2018 Sep; 68(3): 1111–1124. Published online 2018 May 20. doi: 10.1002/hep.29902
PMCID:
PMC6165716
AbstractArticlePDF–3.6M
2.
Coenzyme A–mediated degradation of pyruvate dehydrogenase kinase 4 promotes cardiac metabolic flexibility after high-fat feeding in mice
Christopher Schafer, Zachary T. Young, Catherine A. Makarewich, Abdallah Elnwasany, Caroline Kinter, Michael Kinter, Luke I. Szweda
J Biol Chem. 2018 May 4; 293(18): 6915–6924. Published online 2018 Mar 14. doi: 10.1074/jbc.RA117.000268
PMCID:
PMC5936801
AbstractArticlePDF–1.5M
3.
Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells
A G Trinidad, N Whalley, R Rowlinson, O Delpuech, P Dudley, C Rooney, S E Critchlow
Oncogene. 2017 Nov 2; 36(44): 6164–6176. Published online 2017 Jul 10. doi: 10.1038/onc.2017.224
PMCID:
PMC5671936
AbstractArticlePDF–3.5M
4.
Up-regulation of pyruvate dehydrogenase kinase isoform 4 (PDK4) protein expression in oxidative skeletal muscle does not require the obligatory participation of peroxisome-proliferator-activated receptor alpha (PPARalpha).
Mark J Holness, Karen Bulmer, Geoffrey F Gibbons, Mary C Sugden
Biochem J. 2002 Sep 15; 366(Pt 3): 839–846. doi: 10.1042/BJ20020754
PMCID:
PMC1222844
SummaryPDF–205K
5.
Evidence that pyruvate dehydrogenase kinase belongs to the ATPase/kinase superfamily.
M Bowker-Kinley, K M Popov
Biochem J. 1999 Nov 15; 344(Pt 1): 47–53.
PMCID:
PMC1220612
SummaryPDF–280K
6.
Vascular PPARβ/δ Promotes Tumor Angiogenesis and Progression
Kay-Dietrich Wagner, Siyue Du, Luc Martin, Nathalie Leccia, Jean-François Michiels, Nicole Wagner
Cells. 2019 Dec; 8(12): 1623. Published online 2019 Dec 12. doi: 10.3390/cells8121623
PMCID:
PMC6952835
AbstractArticlePDF–23M
7.
Crtc1 Activates a Transcriptional Program Deregulated at Early Alzheimer's Disease-Related Stages
Arnaldo Parra-Damas, Jorge Valero, Meng Chen, Judit España, Elsa Martín, Isidro Ferrer, José Rodríguez-Alvarez, Carlos A. Saura
J Neurosci. 2014 Apr 23; 34(17): 5776–5787. doi: 10.1523/JNEUROSCI.5288-13.2014
PMCID:
PMC6608295
AbstractArticlePDF–2.6M
8.
Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease
Luana Naia, Teresa Cunha-Oliveira, Joana Rodrigues, Tatiana R. Rosenstock, Ana Oliveira, Márcio Ribeiro, Catarina Carmo, Sofia I. Oliveira-Sousa, Ana I. Duarte, Michael R. Hayden, A. Cristina Rego
J Neurosci. 2017 Mar 8; 37(10): 2776–2794. doi: 10.1523/JNEUROSCI.2006-14.2016
PMCID:
PMC6596633
AbstractArticlePDF–3.9M
9.
Increase in muscle endurance in mice by dietary Yamabushitake mushroom (Hericium erinaceus) possibly via activation of PPARδ
Yusuke Komiya, Toshiya Nakamura, Momoko Ishii, Kuniyoshi Shimizu, Eri Hiraki, Fuminori Kawabata, Mako Nakamura, Ryuichi Tatsumi, Yoshihide Ikeuchi, Wataru Mizunoya
Anim Sci J. 2019 Jun; 90(6): 781–789. Published online 2019 Apr 1. doi: 10.1111/asj.13199
PMCID:
PMC6594082
AbstractArticlePDF–1.0M
10.
Temporal Integrative Analysis of mRNA and microRNAs Expression Profiles and Epigenetic Alterations in Female SAMP8, a Model of Age-Related Cognitive Decline
Marta Cosín-Tomás, María Jesús Álvarez-López, Júlia Companys-Alemany, Perla Kaliman, Celia González-Castillo, Daniel Ortuño-Sahagún, Mercè Pallàs, Christian Griñán-Ferré
Front Genet. 2018; 9: 596. Published online 2018 Dec 11. doi: 10.3389/fgene.2018.00596
PMCID:
PMC6297390
AbstractArticlePDF–3.4M
11.
Remodeling of skeletal muscle mitochondrial proteome with high-fat diet involves greater changes to β-oxidation than electron transfer proteins in mice
Surendra Dasari, Sean A. Newsom, Sarah E. Ehrlicher, Harrison D. Stierwalt, Matthew M. Robinson
Am J Physiol Endocrinol Metab. 2018 Oct 1; 315(4): E425–E434. Published online 2018 May 29. doi: 10.1152/ajpendo.00051.2018
PMCID:
PMC6230708
AbstractArticle
12.
Specific Physical Exercise Improves Energetic Metabolism in the Skeletal Muscle of Amyotrophic-Lateral- Sclerosis Mice
Céline Desseille, Séverine Deforges, Olivier Biondi, Léo Houdebine, Domenico D’amico, Antonin Lamazière, Cédric Caradeuc, Gildas Bertho, Gaëlle Bruneteau, Laure Weill, Jean Bastin, Fatima Djouadi, François Salachas, Philippe Lopes, Christophe Chanoine, Charbel Massaad, Frédéric Charbonnier
Front Mol Neurosci. 2017; 10: 332. Published online 2017 Oct 20. doi: 10.3389/fnmol.2017.00332
PMCID:
PMC5655117
AbstractArticlePDF–3.2M
13.
Supramolecular structure of dietary fat in early life modulates expression of markers for mitochondrial content and capacity in adipose tissue of adult mice
Andrea Kodde, Eline M. van der Beek, Esther Phielix, Eefje Engels, Lidewij Schipper, Annemarie Oosting
Nutr Metab (Lond) 2017; 14: 37. Published online 2017 Jun 12. doi: 10.1186/s12986-017-0191-5
PMCID:
PMC5469001
AbstractArticlePDF–1.1M
14.
CD36 is essential for endurance improvement, changes in whole‐body metabolism, and efficient PPAR‐related transcriptional responses in the muscle with exercise training
Mark Christian C. Manio, Shigenobu Matsumura, Daisaku Masuda, Kazuo Inoue
Physiol Rep. 2017 May; 5(10): e13282. Published online 2017 May 19. doi: 10.14814/phy2.13282
PMCID:
PMC5449563
AbstractArticlePDF–1.2M
15.
The PPARγ2 A/B-Domain Plays a Gene-Specific Role in Transactivation and Cofactor Recruitment
Anne Bugge, Lars Grøntved, Mads M. Aagaard, Rehannah Borup, Susanne Mandrup
Mol Endocrinol. June 1, 2009; 23(6): 794–808. doi: 10.1210/me.2008-0236
PMCID:
PMC5419289
AbstractArticle
16.
PPARβ Activation Induces Rapid Changes of Both AMPK Subunit Expression and AMPK Activation in Mouse Skeletal Muscle
E. Lendoye, B. Sibille, A-S. Rousseau, J. Murdaca, P. A. Grimaldi, P. Lopez
Mol Endocrinol. September 1, 2011; 25(9): 1487–1498. Published online 2011 Jul 28. doi: 10.1210/me.2010-0504
PMCID:
PMC5417230
AbstractArticle
17.
Metabolic Response of Visceral White Adipose Tissue of Obese Mice Exposed for 5 Days to Human Room Temperature Compared to Mouse Thermoneutrality
Inge van der Stelt, Femke Hoevenaars, Jitka Široká, Lidwien de Ronde, David Friedecký, Jaap Keijer, Evert van Schothorst
Front Physiol. 2017; 8: 179. Published online 2017 Mar 23. doi: 10.3389/fphys.2017.00179
PMCID:
PMC5362617
AbstractArticlePDF–2.4M
18.
Imidacloprid Promotes High Fat Diet-Induced Adiposity and Insulin Resistance in Male C57BL/6J Mice
Quancai Sun, Xiao Xiao, Yoo Kim, Daeyoung Kim, Kyoon Sup Yoon, John M. Clark, Yeonhwa Park
J Agric Food Chem. 2016 Dec 14; 64(49): 9293–9306. Published online 2016 Nov 17. doi: 10.1021/acs.jafc.6b04322
PMCID:
PMC5325319
AbstractArticlePDF–5.3M
19.
NEURON-SPECIFIC SUMO KNOCKDOWN SUPPRESSES GLOBAL GENE EXPRESSION RESPONSE AND WORSENS FUNCTIONAL OUTCOME AFTER TRANSIENT FOREBRAIN ISCHEMIA IN MICE
LIN ZHANG, XIAOZHI LIU, HUAXIN SHENG, SHUAI LIU, YING LI, JULIA Q. ZHAO, DAVID S. WARNER, WULF PASCHEN, WEI YANG
Neuroscience. Author manuscript; available in PMC 2018 Feb 20.
Published in final edited form as: Neuroscience. 2017 Feb 20; 343: 190–212. Published online 2016 Dec 3. doi: 10.1016/j.neuroscience.2016.11.036
PMCID:
PMC5319602
AbstractArticlePDF–1.7M
20.
On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
Mark A. Cole, Amira H. Abd Jamil, Lisa C. Heather, Andrew J. Murray, Elizabeth R. Sutton, Mary Slingo, Liam Sebag-Montefiore, Suat Cheng Tan, Dunja Aksentijević, Ottilie S. Gildea, Daniel J. Stuckey, Kar Kheng Yeoh, Carolyn A. Carr, Rhys D. Evans, Ellen Aasum, Christopher J. Schofield, Peter J. Ratcliffe, Stefan Neubauer, Peter A. Robbins, Kieran Clarke
FASEB J. 2016 Aug; 30(8): 2684–2697. Published online 2016 Apr 21. doi: 10.1096/fj.201500094R
PMCID:
PMC5072355
AbstractArticle

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