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Select item 38998121.

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment

Asha Seth, Jianming Ye, Nanjia Yu, Fanny Guez, David C. Bedford, Geoffrey A. Neale, Sabine Cordi, Paul K. Brindle, Frederic P. Lemaigre, Klaus H. Kaestner, Beatriz Sosa-Pineda

Development. 2014 Feb 1; 141(3): 538–547. doi: 10.1242/dev.099481

PMCID:: PMC3899812

Abstract Article

Select item 59969752.

Nuclear BAP1 loss is common in intrahepatic cholangiocarcinoma and a subtype of hepatocellular carcinoma but rare in pancreatic ductal adenocarcinoma

Asmaa Mosbeh, Khalil Halfawy, Wael S. Abdel-Mageed, Dina Sweed, Mohamed H. Abdel Rahman

Cancer Genet. Author manuscript; available in PMC 2019 Aug 1.

Published in final edited form as: Cancer Genet. 2018 Aug; 224-225: 21–28. Published online 2018 Apr 9. doi: 10.1016/j.cancergen.2018.03.002

PMCID:: PMC5996975

Abstract Article PDF–571K

Select item 59258093.

The transcription factor Klf5 is essential for intrahepatic biliary epithelial tissue remodeling after cholestatic liver injury

Hajime Okada, Minami Yamada, Kenji Kamimoto, Cindy Yuet-Yin Kok, Kota Kaneko, Masatsugu Ema, Atsushi Miyajima, Tohru Itoh

J Biol Chem. 2018 Apr 27; 293(17): 6214–6229. Published online 2018 Mar 9. doi: 10.1074/jbc.RA118.002372

PMCID:: PMC5925809

Abstract Article PDF–4.0M

Select item 110613774.

Bortezomib in previously treated phosphatase and tension homology‐deficient patients with advanced intrahepatic cholangiocarcinoma: An open‐label, prospective and single‐centre phase II trial

Tian‐mei Zeng, Tian‐yi Jiang, Guang Yang, Zhuo Cheng, Cheng Lou, Wei Wei, Chen‐jie Tao, Shouzi Hu, Hui Wang, Xiao‐wen Cui, Ye‐xiong Tan, Li‐wei Dong, Hong‐yang Wang, Zhen‐gang Yuan

Clin Transl Med. 2024 May; 14(5): e1675. Published online 2024 Apr 30. doi: 10.1002/ctm2.1675

PMCID:: PMC11061377

Abstract Article PDF–6.7M

Select item 52365165.

Vanishing bile duct syndrome in Hodgkin’s lymphoma: A case report and literature review

Mena Bakhit, Thomas R McCarty, Sunhee Park, Basile Njei, Margaret Cho, Raffi Karagozian, AnnMarie Liapakis

World J Gastroenterol. 2017 Jan 14; 23(2): 366–372. Published online 2017 Jan 14. doi: 10.3748/wjg.v23.i2.366

PMCID:: PMC5236516

Abstract Article PDF–1.1M

Select item 51199506.

Antitumor effect of FGFR inhibitors on a novel cholangiocarcinoma patient derived xenograft mouse model endogenously expressing an FGFR2-CCDC6 fusion protein

Yu Wang, Xiwei Ding, Shaoqing Wang, Catherine D. Moser, Hassan M. Shaleh, Essa A. Mohamed, Roongruedee Chaiteerakij, Loretta K. Allotey, Gang Chen, Katsuyuki Miyabe, Melissa S. McNulty, Albert Ndzengue, Ryan A. Knudson, Patricia T. Greipp, Karl J. Clark, Michael S. Torbenson, Benjamin R. Kipp, Jie Zhou, Michael T. Barrett, Michael P. Gustafson, Steven R. Alberts, Mitesh J. Borad, Lewis R. Roberts

Cancer Lett. Author manuscript; available in PMC 2017 Sep 28.

Published in final edited form as: Cancer Lett. 2016 Sep 28; 380(1): 163–173. Published online 2016 May 20. doi: 10.1016/j.canlet.2016.05.017

PMCID:: PMC5119950

Abstract Article PDF–2.4M

Select item 47266797.

Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

Ning Ding, Li Che, Xiao-Lei Li, Yan Liu, Li-Jie Jiang, Biao Fan, Jun-Yan Tao, Xin Chen, Jia-Fu Ji

World J Gastroenterol. 2016 Feb 14; 22(6): 2071–2080. Published online 2016 Feb 14. doi: 10.3748/wjg.v22.i6.2071

PMCID:: PMC4726679

Abstract Article PDF–3.0M

Select item 47187478.

Jagged1 heterozygosity in mice results in a congenital cholangiopathy which is reversed by concomitant deletion of one copy of Poglut1 (Rumi)

Shakeel M. Thakurdas, Mario F. Lopez, Shinako Kakuda, Rodrigo Fernandez-Valdivia, Neda Zarrin-Khameh, Robert S. Haltiwanger, Hamed Jafar-Nejad

Hepatology. Author manuscript; available in PMC 2017 Feb 1.

Published in final edited form as: Hepatology. 2016 Feb; 63(2): 550–565. Published online 2015 Oct 20. doi: 10.1002/hep.28024

PMCID:: PMC4718747

Abstract Article PDF–4.0M

Select item 47118269.

Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

Miki Nishio, Keishi Sugimachi, Hiroki Goto, Jia Wang, Takumi Morikawa, Yosuke Miyachi, Yusuke Takano, Hiroki Hikasa, Tohru Itoh, Satoshi O. Suzuki, Hiroki Kurihara, Shinichi Aishima, Andrew Leask, Takehiko Sasaki, Toru Nakano, Hiroshi Nishina, Yuji Nishikawa, Yoshitaka Sekido, Kazuwa Nakao, Kazuo Shin-ya, Koshi Mimori, Akira Suzuki

Proc Natl Acad Sci U S A. 2016 Jan 5; 113(1): E71–E80. Published online 2015 Dec 22. doi: 10.1073/pnas.1517188113

PMCID:: PMC4711826

Abstract Article PDF–2.6M

Select item 453741410.

Recruited metastasis suppressor NM23-H2 attenuates expression and activity of peroxisome proliferator-activated receptor (PPAR) in human cholangiocarcinoma

Fang He, J. Philippe York, Sherilyn Gordon Burroughs, Lidong Qin, Jintang Xia, De Chen, Eamonn M. Quigley, Paul Webb, Gene D. LeSage, Xuefeng Xia

Dig Liver Dis. Author manuscript; available in PMC 2015 Aug 14.

Published in final edited form as: Dig Liver Dis. 2015 Jan; 47(1): 62–67. Published online 2014 Sep 29. doi: 10.1016/j.dld.2014.09.002

PMCID:: PMC4537414

Abstract Article PDF–980K

Select item 446743911.

FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells

Hui Yang, Xiaofei Lu, Ziming Liu, Lili Chen, Yunfei Xu, Yuli Wang, Guangwei Wei, Yuxin Chen

Oncotarget. 2015 Mar 20; 6(8): 6310–6325. Published online 2015 Jan 31. doi: 10.18632/oncotarget.3355

PMCID:: PMC4467439

Abstract Article PDF–11M

Select item 419940012.

Inspissated bile syndrome in an infant with citrin deficiency and congenital anomalies of the biliary tract and esophagus: Identification and pathogenicity analysis of a novel SLC25A13 mutation with incomplete penetrance

HAN-SHI ZENG, SHU-TAO ZHAO, MEI DENG, ZHAN-HUI ZHANG, XIANG-RAN CAI, FENG-PING CHEN, YUAN-ZONG SONG

Int J Mol Med. 2014 Nov; 34(5): 1241–1248. Published online 2014 Sep 10. doi: 10.3892/ijmm.2014.1929

PMCID:: PMC4199400

Abstract Article PDF–991K

Select item 414950013.

Aberrant Expression of NF-κB in Liver Fluke Associated Cholangiocarcinoma: Implications for Targeted Therapy

Wunchana Seubwai, Chaisiri Wongkham, Anucha Puapairoj, Narong Khuntikeo, Ake Pugkhem, Chariya Hahnvajanawong, Jariya Chaiyagool, Kazuo Umezawa, Seiji Okada, Sopit Wongkham

PLoS One. 2014; 9(8): e106056. Published online 2014 Aug 29. doi: 10.1371/journal.pone.0106056

PMCID:: PMC4149500

Abstract Article PDF–2.1M

Select item 408746814.

Immunohistochemical expression of mismatch repair genes: A screening tool for predicting mutator phenotype in liver fluke infection-associated intrahepatic cholangiocarcinoma

Upama Liengswangwong, Anant Karalak, Yukio Morishita, Masayuki Noguchi, Thiravud Khuhaprema, Petcharin Srivatanakul, Masanao Miwa

World J Gastroenterol. 2006 Jun 21; 12(23): 3740–3745. Published online 2006 Jun 21. doi: 10.3748/wjg.v12.i23.3740

PMCID:: PMC4087468

Abstract Article PDF–827K

Select item 405737515.

LITHOCHOLIC ACID FEEDING RESULTS IN DIRECT HEPATO-TOXICITY INDEPENDENT OF NEUTROPHIL FUNCTION IN MICE

Benjamin L. Woolbright, Feng Li, Yuchao Xie, Anwar Farhood, Peter Fickert, Michael Trauner, Hartmut Jaeschke

Toxicol Lett. Author manuscript; available in PMC 2015 Jul 3.

Published in final edited form as: Toxicol Lett. 2014 Jul 3; 228(1): 56–66. Published online 2014 Apr 15. doi: 10.1016/j.toxlet.2014.04.001

PMCID:: PMC4057375

Abstract Article PDF–910K

Select item 404933416.

Peroxisome Proliferator-Activated Receptor α Activates Human Multidrug Resistance Transporter 3/ATP-Binding Cassette Protein Subfamily B4 Transcription and Increases Rat Biliary Phosphatidylcholine Secretion

Nisanne S. Ghonem, Meenakshisundaram Ananthanarayanan, Carol J. Soroka, James L. Boyer

Hepatology. Author manuscript; available in PMC 2014 Jun 9.

Published in final edited form as: Hepatology. 2014 Mar; 59(3): 1030–1042. Published online 2014 Jan 27. doi: 10.1002/hep.26894

PMCID:: PMC4049334

Abstract Article PDF–1.0M

Select item 590195917.

The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals

Nan Wu, Quy Nguyen, Ying Wan, Tiaohao Zhou, Julie Venter, Gabriel A Frampton, Sharon DeMorrow, Duojia Pan, Fanyin Meng, Shannon Glaser, Gianfranco Alpini, Haibo Bai

Lab Invest. Author manuscript; available in PMC 2018 Apr 16.

Published in final edited form as: Lab Invest. 2017 Jul; 97(7): 843–853. Published online 2017 Jun 5. doi: 10.1038/labinvest.2017.29