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Select item 3343841.

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

M H Koken, C Vreeken, S A Bol, N C Cheng, I Jaspers-Dekker, J H Hoeijmakers, J C Eeken, G Weeda, A Pastink

Nucleic Acids Res. 1992 Nov 11; 20(21): 5541–5548. doi: 10.1093/nar/20.21.5541

PMCID:: PMC334384

Summary Page Browse PDF–2.0M

Select item 864262.

Mechanism of Promoter Melting by the Xeroderma Pigmentosum Complementation Group B Helicase of Transcription Factor IIH Revealed by Protein-DNA Photo-Cross-Linking

Maxime Douziech, Frédéric Coin, Jean-Marc Chipoulet, Yoko Arai, Yoshiaki Ohkuma, Jean-Marc Egly, Benoit Coulombe

Mol Cell Biol. 2000 Nov; 20(21): 8168–8177. doi: 10.1128/mcb.20.21.8168-8177.2000

PMCID:: PMC86426

Article PDF–3.1M

Select item 109722703.

Relationship between XPA, XPB/ERCC3, XPF/ERCC4, and XPG/ERCC5 Polymorphisms and the Susceptibility to Head and Neck Carcinoma: A Systematic Review, Meta-Analysis, and Trial Sequential Analysis

Mohammad Moslem Imani, Masoumeh Basamtabar, Sattar Akbari, Edris Sadeghi, Masoud Sadeghi

Medicina (Kaunas) 2024 Mar; 60(3): 478. Published online 2024 Mar 14. doi: 10.3390/medicina60030478

PMCID:: PMC10972270

Article PDF–837K

Select item 95577304.

Systematic mutagenesis of TFIIH subunit p52/Tfb2 identifies residues required for XPB/Ssl2 subunit function and genetic interactions with TFB6

Jacob Bassett, Jenna K. Rimel, Shrabani Basu, Pratik Basnet, Jie Luo, Krysta L. Engel, Michael Nagel, Alexander Woyciehowsky, Christopher C. Ebmeier, Craig D. Kaplan, Dylan J. Taatjes, Jeffrey A. Ranish

J Biol Chem. 2022 Oct; 298(10): 102433. Published online 2022 Aug 28. doi: 10.1016/j.jbc.2022.102433

PMCID:: PMC9557730

Article PDF–4.6M

Select item 94584335.

Differential dependencies of human RNA polymerase II promoters on TBP, TAF1, TFIIB and XPB

Juan F Santana, Geoffrey S Collins, Mrutyunjaya Parida, Donal S Luse, David H Price

Nucleic Acids Res. 2022 Sep 9; 50(16): 9127–9148. Published online 2022 Aug 10. doi: 10.1093/nar/gkac678

PMCID:: PMC9458433

Article PDF–8.8M

Select item 86593836.

Topical Treatment of Human Skin and Cultured Keratinocytes with High-Dose Spironolactone Reduces XPB Expression and Induces Toxicity

M. Alexandra Carpenter, Michael G. Kemp

JID Innov. 2021 Sep; 1(3): 100023. Published online 2021 May 6. doi: 10.1016/j.xjidi.2021.100023

PMCID:: PMC8659383

Article PDF–1.2M

Select item 83273647.

The role of XPB/Ssl2 dsDNA translocation processivity in transcription-start-site scanning.

Eric J. Tomko, Olivia Luyties, Jenna K. Rimel, Chi-Lin Tsai, Jill O. Fuss, James Fishburn, Steven Hahn, Susan E. Tsutakawa, Dylan J. Taatjes, Eric A. Galburt

J Mol Biol. Author manuscript; available in PMC 2022 Jul 9.

Published in final edited form as: J Mol Biol. 2021 Jul 9; 433(14): 166813. Published online 2021 Jan 13. doi: 10.1016/j.jmb.2021.166813

PMCID:: PMC8327364

Article PDF–1.1M

Select item 78515598.

The XPB Subunit of the TFIIH Complex Plays a Critical Role in HIV-1 Transcription, and XPB Inhibition by Spironolactone Prevents HIV-1 Reactivation from Latency

Luisa Mori, Katharine Jenike, Yang-Hui Jimmy Yeh, Benoît Lacombe, Chuan Li, Adam J. Getzler, Sonia Mediouni, Michael E. Cameron, Matthew E. Pipkin, Ya-Chi Ho, Bertha Cecilia Ramirez, Susana T. Valente

J Virol. 2021 Feb; 95(4): e01247-20. Prepublished online 2020 Nov 25. Published online 2021 Jan 28. doi: 10.1128/JVI.01247-20

PMCID:: PMC7851559

Article PDF–3.5M

Select item 78497779.

Spironolactone-induced XPB degradation requires TFIIH integrity and ubiquitin-selective segregase VCP/p97

Anil K. Chauhan, Ping Li, Yingming Sun, Gulzar Wani, Qianzheng Zhu, Altaf A. Wani

Cell Cycle. 2021; 20(1): 81–95. Published online 2020 Dec 31. doi: 10.1080/15384101.2020.1860559

PMCID:: PMC7849777

Article PDF–2.0M

Select item 772067710.

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

Jue Er Amanda Lee, Naomi C. Mitchell, Olga Zaytseva, Arjun Chahal, Peter Mendis, Amandine Cartier-Michaud, Linda M. Parsons, Gretchen Poortinga, David L. Levens, Ross D. Hannan, Leonie M. Quinn

Nat Commun. Author manuscript; available in PMC 2020 Dec 7.

Published in final edited form as: Nat Commun. 2015 Jun 15; 6: 7404. Published online 2015 Jun 15. doi: 10.1038/ncomms8404

PMCID:: PMC7720677

Article PDF–2.9M

Select item 770807811.

How to limit the speed of a motor: the intricate regulation of the XPB ATPase and translocase in TFIIH

Jeannette Kappenberger, Wolfgang Koelmel, Elisabeth Schoenwetter, Tobias Scheuer, Julia Woerner, Jochen Kuper, Caroline Kisker

Nucleic Acids Res. 2020 Dec 2; 48(21): 12282–12296. Published online 2020 Nov 16. doi: 10.1093/nar/gkaa911

PMCID:: PMC7708078

Article PDF–2.3M

Select item 767244312.

Structural basis of the XPB helicase–Bax1 nuclease complex interacting with the repair bubble DNA

Feng He, Kevin DuPrez, Eduardo Hilario, Zhenhang Chen, Li Fan

Nucleic Acids Res. 2020 Nov 18; 48(20): 11695–11705. Published online 2020 Sep 28. doi: 10.1093/nar/gkaa801

PMCID:: PMC7672443

Article PDF–5.5M

Select item 729370813.

Epstein–Barr virus co-opts TFIIH component XPB to specifically activate essential viral lytic promoters

Dinesh Verma, Trenton Mel Church, Sankar Swaminathan

Proc Natl Acad Sci U S A. 2020 Jun 9; 117(23): 13044–13055. Published online 2020 May 20. doi: 10.1073/pnas.2000625117

PMCID:: PMC7293708

Article PDF–1.6M

Select item 729301514.

Structural basis of the XPB–Bax1 complex as a dynamic helicase–nuclease machinery for DNA repair

Kevin DuPrez, Feng He, Zhenhang Chen, Eduardo Hilario, Li Fan

Nucleic Acids Res. 2020 Jun 19; 48(11): 6326–6339. Published online 2020 May 6. doi: 10.1093/nar/gkaa324

PMCID:: PMC7293015

Article PDF–7.4M

Select item 727740915.

Spironolactone and XPB: An Old Drug with a New Molecular Target

Ryan D. Gabbard, Robert R. Hoopes, Michael G. Kemp

Biomolecules. 2020 May; 10(5): 756. Published online 2020 May 13. doi: 10.3390/biom10050756

PMCID:: PMC7277409

Article PDF–2.4M

Select item 710883716.

Human T-Cell Lymphotropic Virus Type 1 Transactivator Tax Exploits the XPB Subunit of TFIIH during Viral Transcription

Christophe Martella, Armelle Inge Tollenaere, Laetitia Waast, Benoit Lacombe, Damien Groussaud, Florence Margottin-Goguet, Bertha Cecilia Ramirez, Claudine Pique

J Virol. 2020 Apr; 94(8): e02171-19. Prepublished online 2020 Feb 5. Published online 2020 Mar 31. doi: 10.1128/JVI.02171-19

PMCID:: PMC7108837

Article PDF–3.1M

Select item 673424017.

Cell-type specific concentration regulation of the basal transcription factor TFIIH in XPB^y/y mice model

Lise-Marie Donnio, Catherine Miquel, Wim Vermeulen, Giuseppina Giglia-Mari, Pierre-Olivier Mari

Cancer Cell Int. 2019; 19: 237. Published online 2019 Sep 10. doi: 10.1186/s12935-019-0945-4

PMCID:: PMC6734240

Article PDF–1.8M

Select item 634263518.

Spironolactone depletes the XPB protein and inhibits DNA damage responses in UVB-irradiated human skin

Michael G. Kemp, Smita Krishnamurthy, Michael N. Kent, David L. Schumacher, Priyanka Sharma, Katherine J.D.A. Excoffon, Jeffrey B. Travers, Society for Investigative Dermatology

J Invest Dermatol. Author manuscript; available in PMC 2020 Feb 1.

Published in final edited form as: J Invest Dermatol. 2019 Feb; 139(2): 448–454. Published online 2018 Sep 15. doi: 10.1016/j.jid.2018.07.039