PMC Articles for MedGen (Select 56350) - PMC

Result Filters

Links from MedGen

Items: 1 to 20 of 1794

<< First< Prev

Page of 90

Select item 112160061.

Icanbelimod (CBP-307), a next-generation Sphingosine-1-phosphate receptor modulator, in healthy men: pharmacokinetics, pharmacodynamics, safety, and tolerability in a randomized trial in Australia

Jason Lickliter, Xin Yang, Jiawang Guo, Wubin Pan, Zheng Wei

Front Immunol. 2024; 15: 1380975. Published online 2024 Jun 17. doi: 10.3389/fimmu.2024.1380975

PMCID:: PMC11216006

Abstract Article PDF–2.5M

Select item 112055792.

CBP Expression Contributes to Neuropathic Pain via CREB and MeCP2 Regulation in the Spared Nerve Injury Rat Model

Chae-Chil Lee, Ki-Bong Park, Min Seok Kim, Young Dae Jeon

Medicina (Kaunas) 2024 Jun; 60(6): 989. Published online 2024 Jun 17. doi: 10.3390/medicina60060989

PMCID:: PMC11205579

Abstract Article PDF–6.5M

Select item 112021273.

CBP/P300 Inhibition Impairs CD4+ T Cell Activation: Implications for Autoimmune Disorders

Lucas Wilhelmus Picavet, Anoushka A. K. Samat, Jorg Calis, Lotte Nijhuis, Rianne Scholman, Michal Mokry, David F. Tough, Rabinder K. Prinjha, Sebastiaan J. Vastert, Jorg van Loosdregt

Biomedicines. 2024 Jun; 12(6): 1344. Published online 2024 Jun 18. doi: 10.3390/biomedicines12061344

PMCID:: PMC11202127

Abstract Article PDF–2.5M

Select item 112017184.

3D Chromatin Alteration by Disrupting β-Catenin/CBP Interaction Is Enriched with Insulin Signaling in Pancreatic Cancer

Yufan Zhou, Zhijing He, Tian Li, Lavanya Choppavarapu, Xiaohui Hu, Ruifeng Cao, Gustavo W. Leone, Michael Kahn, Victor X. Jin

Cancers (Basel) 2024 Jun; 16(12): 2202. Published online 2024 Jun 12. doi: 10.3390/cancers16122202

PMCID:: PMC11201718

Abstract Article PDF–1.9M

Select item 111784985.

The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemia

Guangming Wang, Wenjun Zhang, Jie Ren, Yu Zeng, Xiuyong Dang, Xiaoxue Tian, Wenlei Yu, Zheng Li, Yuting Ma, Pingping Yang, Jinyuan Lu, Junke Zheng, Bing Lu, Jun Xu, Aibin Liang

Oncogene. 2024; 43(25): 1900–1916. Published online 2024 Apr 26. doi: 10.1038/s41388-024-02998-2

PMCID:: PMC11178498

Abstract Article PDF–5.2M

Select item 111674396.

Transcriptional synergy in human aortic endothelial cells is vulnerable to combination p300/CBP and BET bromodomain inhibition

Ronan C. Bracken, Lindsay M. Davison, Dennis P. Buehler, Maci E. Fulton, Emily E. Carson, Quanhu Sheng, Lindsey K. Stolze, Christelle Guillermier, Matthew L. Steinhauser, Jonathan D. Brown

iScience. 2024 Jun 21; 27(6): 110011. Published online 2024 May 16. doi: 10.1016/j.isci.2024.110011

PMCID:: PMC11167439

Abstract Article PDF–14M

Select item 111586347.

P300/CBP‐associated factor regulates Y‐box binding protein‐1 expression and promotes cancer cell growth, cancer invasion and drug resistance

Masaki Shiota, Akira Yokomizo, Yasuhiro Tada, Takeshi Uchiumi, Junichi Inokuchi, Katsunori Tatsugami, Kentaro Kuroiwa, Ken Yamamoto, Narihito Seki, Seiji Naito

Cancer Sci. 2010 Aug; 101(8): 1797–1806. Published online 2010 Apr 23. doi: 10.1111/j.1349-7006.2010.01598.x

PMCID:: PMC11158634

Abstract Article PDF–808K

Select item 111535948.

Targeting dependency on a paralog pair of CBP/p300 against de-repression of KREMEN2 in SMARCB1-deficient cancers

Mariko Sasaki, Daiki Kato, Karin Murakami, Hiroshi Yoshida, Shohei Takase, Tsuguteru Otsubo, Hideaki Ogiwara

Nat Commun. 2024; 15: 4770. Published online 2024 Jun 5. doi: 10.1038/s41467-024-49063-w

PMCID:: PMC11153594

Abstract Article PDF–2.3M

Select item 111131699.

Transcriptional/epigenetic regulator CBP/p300 in tumorigenesis: structural and functional versatility in target recognition

Feng Wang, Christopher B. Marshall, Mitsuhiko Ikura

Cell Mol Life Sci. 2013 Nov; 70(21): 3989–4008. Published online 2013 Jan 11. doi: 10.1007/s00018-012-1254-4

PMCID:: PMC11113169

Abstract Article PDF–1.5M

Select item 1110568410.

CBP-mediated SMN acetylation modulates Cajal body biogenesis and the cytoplasmic targeting of SMN

Vanesa Lafarga, Olga Tapia, Sahil Sharma, Rocio Bengoechea, Georg Stoecklin, Miguel Lafarga, Maria T. Berciano

Cell Mol Life Sci. 2018 Feb; 75(3): 527–546. Published online 2017 Sep 6. doi: 10.1007/s00018-017-2638-2

PMCID:: PMC11105684

Abstract Article PDF–11M

Select item 1110073011.

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

Sumaira Sardar, Christopher M. McNair, Lakshmi Ravindranath, Saswati N. Chand, Wei Yuan, Denisa Bogdan, Jon Welti, Adam Sharp, Natalie K. Ryan, Matthew J. Schiewer, Elise G. DeArment, Thomas Janas, Xiaofeng A. Su, Lisa M. Butler, Johann S. de Bono, Kris Frese, Nigel Brooks, Neil Pegg, Karen E. Knudsen, Ayesha A. Shafi

Version 1. bioRxiv. Preprint. 2024 May 7. doi: 10.1101/2024.05.07.592966

Published in:: Oncogene. 2024 Sep 13

PMCID:: PMC11100730

Abstract Article PDF–5.8M

Select item 1107162812.

CBP/P300 BRD Inhibition Reduces Neutrophil Accumulation and Activates Antitumor Immunity in TNBC

Xueying Yuan, Xiaoxin Hao, Hilda L. Chan, Na Zhao, Diego A. Pedroza, Fengshuo Liu, Kang Le, Alex J. Smith, Sebastian J. Calderon, Nadia Lieu, Michael J. Soth, Philip Jones, Xiang H.-F. Zhang, Jeffrey M. Rosen

Version 1. bioRxiv. Preprint. 2024 Apr 27. doi: 10.1101/2024.04.25.590983

Published in:: JCI Insight. 2024 Sep 17

PMCID:: PMC11071628

Abstract Article PDF–1.2M

Select item 1104575713.

Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition

Noha A. M. Shendy, Melissa Bikowitz, Logan H. Sigua, Yang Zhang, Audrey Mercier, Yousef Khashana, Stephanie Nance, Qi Liu, Ian M. Delahunty, Sarah Robinson, Vanshita Goel, Matthew G. Rees, Melissa A. Ronan, Tingjian Wang, Mustafa Kocak, Jennifer A. Roth, Yingzhe Wang, Burgess B. Freeman, Brent A. Orr, Brian J. Abraham, Martine F. Roussel, Ernst Schonbrunn, Jun Qi, Adam D. Durbin

Nat Commun. 2024; 15: 3483. Published online 2024 Apr 25. doi: 10.1038/s41467-024-47102-0

PMCID:: PMC11045757

Abstract Article PDF–4.7M

Select item 1099670914.

p300/CBP degradation is required to disable the active AR enhanceosome in prostate cancer

Jie Luo, Zhixiang Chen, Yuanyuan Qiao, Jean Ching-Yi Tien, Eleanor Young, Rahul Mannan, Somnath Mahapatra, Tongchen He, Sanjana Eyunni, Yuping Zhang, Yang Zheng, Fengyun Su, Xuhong Cao, Rui Wang, Yunhui Cheng, Rithvik Seri, James George, Miriam Shahine, Stephanie J. Miner, Ulka Vaishampayan, Mi Wang, Shaomeng Wang, Abhijit Parolia, Arul M. Chinnaiyan

Version 2. bioRxiv. Preprint. 2024 Mar 30 [revised 2024 May 23]. doi: 10.1101/2024.03.29.587346

PMCID:: PMC10996709

Abstract Article PDF–3.7M

Select item 1098006915.

Neuronal CBP-1 is required for enhanced body muscle proteostasis in response to reduced translation downstream of mTOR

Santina Snow, Dilawar Mir, Zhengxin Ma, Jordan Horrocks, Matthew Cox, Marissa Ruzga, Hussein Sayed, Aric N. Rogers

Version 1. bioRxiv. Preprint. 2024 Mar 17. doi: 10.1101/2024.03.15.585263

Published in:: Front Biosci (Landmark Ed). 2024 Jul 23; 29(7): 264.

PMCID:: PMC10980069

Abstract Article

Select item 1095750116.

Selective Modulation of the Human Glucocorticoid Receptor Compromises GR Chromatin Occupancy and Recruitment of p300/CBP and the Mediator Complex

Laura Van Moortel, Annick Verhee, Jonathan Thommis, René Houtman, Diana Melchers, Louis Delhaye, Chloé Van Leene, Madeleine Hellemans, Kris Gevaert, Sven Eyckerman, Karolien De Bosscher

Mol Cell Proteomics. 2024 Mar; 23(3): 100741. Published online 2024 Feb 20. doi: 10.1016/j.mcpro.2024.100741

PMCID:: PMC10957501

Abstract Article PDF–3.0M

Select item 1094411517.

SADS-CoV nsp1 inhibits the STAT1 phosphorylation by promoting K11/K48-linked polyubiquitination of JAK1 and blocks the STAT1 acetylation by degrading CBP

Yingjie Xiang, Chunxiao Mou, Liqi Zhu, Ziyan Wang, Kaichuang Shi, Wenbin Bao, Jiarui Li, Xiang Chen, Zhenhai Chen

J Biol Chem. 2024 Mar; 300(3): 105779. Published online 2024 Feb 21. doi: 10.1016/j.jbc.2024.105779

PMCID:: PMC10944115

Abstract Article PDF–6.3M

Select item 1094307718.

Plasma extracellular vesicle microRNAs reflecting the therapeutic effect of the CBP/β-catenin inhibitor PRI-724 in patients with liver cirrhosis

Mayu Yoshida, Juntaro Matsuzaki, Koji Fujita, Masamichi Kimura, Tomohiro Umezu, Noi Tokuda, Tomoko Yamaguchi, Masahiko Kuroda, Takahiro Ochiya, Yoshimasa Saito, Kiminori Kimura

Sci Rep. 2024; 14: 6266. Published online 2024 Mar 15. doi: 10.1038/s41598-024-56942-1

PMCID:: PMC10943077

Abstract Article PDF–7.6M

Select item 1092522819.

Insights into post-translational regulation of skeletal muscle contractile function by the acetyltransferases, p300 and CBP

Gretchen A. Meyer, Jeremie L.A. Ferey, James A. Sanford, Liam S. Fitzgerald, Akiva E. Greenberg, Kristoffer Svensson, Michael J. Greenberg, Simon Schenk

Version 1. bioRxiv. Preprint. 2024 Feb 29. doi: 10.1101/2024.02.27.582179

Published in:: J Appl Physiol (1985). 2024 Jun 1; 136(6): 1559–1567.

PMCID:: PMC10925228

Abstract Article

Select item 1090012820.

Covalent Chemical Cochaperones of the p300/CBP GACKIX Domain

Jean M. Lodge, Chinmay Y. Majmudar, James Clayton, Anna K. Mapp

Chembiochem. Author manuscript; available in PMC 2024 Feb 28.

Published in final edited form as: Chembiochem. 2018 Sep 17; 19(18): 1907–1912. Published online 2018 Sep 5. doi: 10.1002/cbic.201800173

PMCID:: PMC10900128

Abstract Article PDF–742K

<< First< Prev

Page of 90

Next >Last >>

Supplemental Content

Filter your results:

Manage Filters

Find related data

Recent activity

Clear Turn Off Turn On

PMC Articles for MedGen (Select 56350) (1794)
PMC
Conserved Domain Links for Gene (Select 150274) (3)
Conserved Domains
Ostreococcus tauri TRAM/LAG1/CLN8 homology domain (OT_ostta13g02920), partial mR...
Ostreococcus tauri TRAM/LAG1/CLN8 homology domain (OT_ostta13g02920), partial mRNA
gi|1275575811|ref|XM_022982770.1|

Nucleotide
Ostreococcus tauri ARID/BRIGHT DNA-binding domain (OT_ostta13g02865), partial mR...
Ostreococcus tauri ARID/BRIGHT DNA-binding domain (OT_ostta13g02865), partial mRNA
gi|1275575799|ref|XM_003082719.2|

Nucleotide
ST13P13 ST13, Hsp70 interacting protein pseudogene 13 [Homo sapiens]
ST13P13 ST13, Hsp70 interacting protein pseudogene 13 [Homo sapiens]
Gene ID:401648

Gene

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PMC

Result Filters

Article attributes

Text availability

Publication date

Custom date range

Research Funder

Additional filters

Display Settings:

Send to: