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Select item 101028461.

Blood-Based Diagnosis and Risk Stratification of Patients with Pancreatic Intraductal Papillary Mucinous Neoplasm (IPMN)

Chaoyang Zhang, Fawaz N. Al-Shaheri, Mohamed Saiel Saeed Alhamdani, Andrea S. Bauer, Jörg D. Hoheisel, Miriam Schenk, Ulf Hinz, Philipp Goedecke, Karam Al-Halabi, Markus W. Büchler, Nathalia A. Giese, Thilo Hackert, Susanne Roth

Clin Cancer Res. 2023 Apr 14; 29(8): 1535–1545. Published online 2022 Dec 14. doi: 10.1158/1078-0432.CCR-22-2531

PMCID:: PMC10102846

Abstract Article PDF–3.5M

Select item 72944582.

Novel Methylated DNA Markers Discriminate Advanced Neoplasia in Pancreatic Cysts: Marker Discovery, Tissue Validation, and Cyst Fluid Testing

Shounak Majumder, William R. Taylor, Tracy C. Yab, Calise K. Berger, Brian A. Dukek, Xiaoming Cao, Patrick H. Foote, Chung Wah Wu, Douglas W. Mahoney, Harry R. Aslanian, Carlos Fernández-Del Castillo, Leona A. Doyle, James J. Farrell, William E. Fisher, Linda S. Lee, Yvonne N. Lee, Walter Park, Clifton Rodrigues, Bonnie Elyssa Gould Rothberg, Ronald R. Salem, Diane M. Simeone, Sumithra Urs, George Van Buren, Thomas C. Smyrk, Hatim T. Allawi, Graham P. Lidgard, Massimo Raimondo, Suresh T. Chari, Michael L. Kendrick, John B. Kisiel, Mark D. Topazian, David A. Ahlquist

Am J Gastroenterol. Author manuscript; available in PMC 2020 Sep 1.

Published in final edited form as: Am J Gastroenterol. 2019 Sep; 114(9): 1539–1549. doi: 10.14309/ajg.0000000000000284

PMCID:: PMC7294458

Abstract Article PDF–1.4M

Select item 72864723.

Identification of key lncRNAs in the tumorigenesis of intraductal pancreatic mucinous neoplasm by coexpression network analysis

Jun Ding, Yi Li, Yong Zhang, Bin Fan, Qinghe Li, Jian Zhang, Jiayao Zhang

Cancer Med. 2020 Jun; 9(11): 3840–3851. Published online 2020 Apr 2. doi: 10.1002/cam4.2927

PMCID:: PMC7286472

Abstract Article PDF–2.2M

Select item 99331744.

Molecular heterogeneity and commonalities in pancreatic cancer precursors with gastric and intestinal phenotype

Sven-Thorsten Liffers, Laura Godfrey, Lisa Frohn, Lena Haeberle, Aslihan Yavas, Rita Vesce, Wolfgang Goering, Friederike V Opitz, Nickolas Stoecklein, Wolfram Trudo Knoefel, Anna Melissa Schlitter, Guenter Klöppel, Elisa Espinet, Andreas Trumpp, Jens T Siveke, Irene Esposito

Gut. 2023 Mar; 72(3): 522–534. Published online 2022 Aug 9. doi: 10.1136/gutjnl-2021-326550

PMCID:: PMC9933174

Abstract Article PDF–5.2M

Select item 99423825.

Utility of promoter hypermethylation in malignant risk stratification of intraductal papillary mucinous neoplasms

Ankit Chhoda, Anup Sharma, Bethsebie Sailo, Haoyu Tang, Nensi Ruzgar, Wan Ying Tan, Lee Ying, Rishabh Khatri, Anand Narayanan, Shrikant Mane, Bony De Kumar, Laura D. Wood, Christine Iacobuzio-Donahue, Christopher L. Wolfgang, John W. Kunstman, Ronald R. Salem, James J. Farrell, Nita Ahuja

Clin Epigenetics. 2023; 15: 28. Published online 2023 Feb 20. doi: 10.1186/s13148-023-01429-5

PMCID:: PMC9942382

Abstract Article PDF–1.2M

Select item 99498936.

Multidimensional Immunophenotyping of Intraductal Papillary Mucinous Neoplasms Reveals Novel T Cell and Macrophage Signature

Austin M. Eckhoff, Ashley A. Fletcher, Karenia Landa, Matthew Iyer, Daniel P. Nussbaum, Chanjuan Shi, Smita K. Nair, Peter J. Allen

Ann Surg Oncol. Author manuscript; available in PMC 2023 Feb 23.

Published in final edited form as: Ann Surg Oncol. 2022 Nov; 29(12): 7781–7788. Published online 2022 Jul 13. doi: 10.1245/s10434-022-12157-0

PMCID:: PMC9949893

Abstract Article PDF–1.1M

Select item 72350277.

Upregulation of follistatin and low apoptotic activity in intraductal oncocytic papillary neoplasm of the pancreatobiliary system

Jun Nakahodo, Yuki Fukumura, Tsuyoshi Saito, Kenichi Hirabayashi, Reiko Doi, Takuo Hayashi, Takashi Yao

Sci Rep. 2020; 10: 8179. Published online 2020 May 18. doi: 10.1038/s41598-020-64920-6

PMCID:: PMC7235027

Abstract Article PDF–2.3M

Select item 71674158.

Macrophage inhibitory cytokine-1/growth differentiation factor-15 in premalignant and neoplastic tumours in a high-risk pancreatic cancer cohort

Robert Sean O’Neill, Sam Emmanuel, David Williams, Alina Stoita

World J Gastroenterol. 2020 Apr 14; 26(14): 1660–1673. Published online 2020 Apr 14. doi: 10.3748/wjg.v26.i14.1660

PMCID:: PMC7167415

Abstract Article PDF–842K

Select item 100229069.

Digital spatial profiling of intraductal papillary mucinous neoplasms: Toward a molecular framework for risk stratification

Matthew K. Iyer, Chanjuan Shi, Austin M. Eckhoff, Ashley Fletcher, Daniel P. Nussbaum, Peter J. Allen

Sci Adv. 2023 Mar; 9(11): eade4582. Published online 2023 Mar 17. doi: 10.1126/sciadv.ade4582

PMCID:: PMC10022906

Abstract Article PDF–2.4M

Select item 991105010.

A pilot study to evaluate tissue- and plasma-based DNA driver mutations in a cohort of patients with pancreatic intraductal papillary mucinous neoplasms

Margaret A Park, Thinzar Zaw, Sean J Yoder, Maria Gomez, Maria Genilo-Delgado, Toni Basinski, Esther Katende, Aamir Dam, Shaffer R S Mok, Alvaro Monteiro, Amir Mohammadi, Daniel K Jeong, Kun Jiang, Barbara A Centeno, Pamela Hodul, Mokenge Malafa, Jason Fleming, Dung-Tsa Chen, Qianxing Mo, Jamie K Teer, Jennifer B Permuth

G3 (Bethesda) 2023 Feb; 13(2): jkac314. Published online 2022 Dec 1. doi: 10.1093/g3journal/jkac314

PMCID:: PMC9911050

Abstract Article PDF–464K

Select item 701055411.

Recurrent Rearrangements in PRKACA and PRKACB in Intraductal Oncocytic Papillary Neoplasms of the Pancreas and Bile Duct

Aatur D. Singhi, Laura D. Wood, Emma Parks, Michael S. Torbenson, Matthäus Felsenstein, Ralph H. Hruban, Marina N. Nikiforova, Abigail I. Wald, Cihan Kaya, Yuri E. Nikiforov, Laura Favazza, Jin He, Kevin McGrath, Kenneth E. Fasanella, Randall E. Brand, Anne Marie Lennon, Alessandro Furlan, Anil K. Dasyam, Amer H. Zureikat, Herbert J. Zeh, Kenneth Lee, David L. Bartlett, Adam Slivka

Gastroenterology. Author manuscript; available in PMC 2021 Feb 1.

Published in final edited form as: Gastroenterology. 2020 Feb; 158(3): 573–582.e2. Published online 2019 Oct 31. doi: 10.1053/j.gastro.2019.10.028

PMCID:: PMC7010554

Abstract Article PDF–1.2M

Select item 1029315512.

NKX3.1 Expression and Molecular Characterization of Secretory Myoepithelial Carcinoma (SMCA): Advancing the Case for a Salivary Mucous Acinar Phenotype

Simmi Patel, Abigail I. Wald, Jassem M. Bastaki, Simon I. Chiosea, Aatur D. Singhi, Raja R. Seethala

Head Neck Pathol. 2023 Jun; 17(2): 467–478. Published online 2023 Feb 6. doi: 10.1007/s12105-023-01524-2

PMCID:: PMC10293155

Abstract Article PDF–3.2M

Select item 681571213.

Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet

Yongde Luo, Yaying Yang, Muyun Liu, Dan Wang, Feng Wang, Yawei Bi, Juntao Ji, Suyun Li, Yan Liu, Rong Chen, Haojie Huang, Xiaojie Wang, Agnieszka K. Swidnicka-Siergiejko, Tobias Janowitz, Semir Beyaz, Guoqiang Wang, Sulan Xu, Agnieszka B. Bialkowska, Catherine K. Luo, Christoph L. Pin, Guang Liang, Xiongbin Lu, Maoxin Wu, Kenneth R. Shroyer, Robert A. Wolff, William Plunkett, Baoan Ji, Zhaoshen Li, Ellen Li, Xiaokun Li, Vincent W. Yang, Craig D. Logsdon, James L. Abbruzzese, Weiqin Lu

Gastroenterology. Author manuscript; available in PMC 2020 Nov 1.

Published in final edited form as: Gastroenterology. 2019 Nov; 157(5): 1413–1428.e11. Published online 2019 Jul 25. doi: 10.1053/j.gastro.2019.07.030

PMCID:: PMC6815712

Abstract Article PDF–1.4M

Select item 679432614.

The TLR7/8 agonist R848 remodels tumor and host responses to promote survival in pancreatic cancer

Katherine A. Michaelis, Mason A. Norgard, Xinxia Zhu, Peter R. Levasseur, Shamilene Sivagnanam, Shannon M. Liudahl, Kevin G. Burfeind, Brennan Olson, Katherine R. Pelz, Diana M. Angeles Ramos, H. Carlo Maurer, Kenneth P. Olive, Lisa M. Coussens, Terry K. Morgan, Daniel L. Marks

Nat Commun. 2019; 10: 4682. Published online 2019 Oct 15. doi: 10.1038/s41467-019-12657-w

Correction in:: Nat Commun. 2019; 10: 5257.

PMCID:: PMC6794326

Abstract Article PDF–3.4M

Select item 1048763415.

Mutation Analysis of Pancreatic Juice and Plasma for the Detection of Pancreatic Cancer

Iris J. M. Levink, Maurice P. H. M. Jansen, Zakia Azmani, Wilfred van IJcken, Ronald van Marion, Maikel P. Peppelenbosch, Djuna L. Cahen, Gwenny M. Fuhler, Marco J. Bruno

Int J Mol Sci. 2023 Sep; 24(17): 13116. Published online 2023 Aug 23. doi: 10.3390/ijms241713116

PMCID:: PMC10487634

Abstract Article PDF–820K

Select item 677363316.

Surveillance for pancreatic cancer in high‐risk individuals

I. C. A. W. Konings, M. I. Canto, J. A. Almario, F. Harinck, P. Saxena, A. L. Lucas, F. Kastrinos, D. C. Whitcomb, R. E. Brand, J. Lachter, G. Malleo, S. Paiella, S. Syngal, J. R. Saltzman, E. M. Stoffel, J. E. van Hooft, R. H. Hruban, J. W. Poley, P. Fockens, M. G. Goggins, M. J. Bruno, on behalf of the International CAncer of the Pancreas Screening (CAPS) Consortium

BJS Open. 2019 Oct; 3(5): 656–665. Published online 2019 Jul 2. doi: 10.1002/bjs5.50180

PMCID:: PMC6773633

Abstract Article PDF–227K

Select item 675695017.

Intraductal Papillary Mucinous Neoplasms Arise from Multiple Independent Clones, Each With Distinct Mutations

Catherine G. Fischer, Violeta Beleva Guthrie, Alicia M. Braxton, Lily Zheng, Pei Wang, Qianqian Song, James F. Griffin, Peter E. Chianchiano, Waki Hosoda, Noushin Niknafs, Simeon Springer, Marco Dal Molin, David Masica, Robert B. Scharpf, Elizabeth D. Thompson, Jin He, Christopher L. Wolfgang, Ralph H. Hruban, Nicholas J. Roberts, Anne Marie Lennon, Yuchen Jiao, Rachel Karchin, Laura D. Wood

Gastroenterology. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Gastroenterology. 2019 Oct; 157(4): 1123–1137.e22. Published online 2019 Jun 5. doi: 10.1053/j.gastro.2019.06.001

PMCID:: PMC6756950

Abstract Article PDF–1.4M

Select item 887963318.

Deficient Rnf43 potentiates hyperactive Kras‐mediated pancreatic preneoplasia initiation and malignant transformation

Xian Zhou, Zhichao Sun, Mengdi Zhang, Xiaoyu Qu, Shuhui Yang, Lianmei Wang, Yanling Jing, Li Li, Weiwei Deng, Fangming Liu, Jin Di, Jie Chen, Jian Wu, Hongbing Zhang

Animal Model Exp Med. 2022 Feb; 5(1): 61–71. Published online 2022 Jan 22. doi: 10.1002/ame2.12203

PMCID:: PMC8879633

Abstract Article PDF–3.7M

Select item 859269819.

Bioinformatic Analysis and Integration of Transcriptome and Proteome Results Identify Key Coding and Noncoding Genes Predicting Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Barsha Saha, Bishnupriya Chhatriya, Swapnila Pramanick, Srikanta Goswami

Biomed Res Int. 2021; 2021: 1056622. Published online 2021 Nov 8. doi: 10.1155/2021/1056622

PMCID:: PMC8592698

Abstract Article PDF–1.2M

Select item 860607020.

Case report: composite pancreatic intraductal papillary mucinous neoplasm and neuroendocrine tumor: a new mixed neuroendocrine-non-neuroendocrine neoplasm?

Jingci Chen, Pengyan Wang, Ke Lv, Weixun Zhou

Diagn Pathol. 2021; 16: 108. Published online 2021 Nov 20. doi: 10.1186/s13000-021-01165-5

PMCID:: PMC8606070

Abstract Article PDF–3.1M

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