U.S. flag

An official website of the United States government

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Links from MedGen

Items: 1 to 20 of 130

1.
Single-Cell Transcriptomic Profiling of the Mouse Testicular Germ Cells Reveals Important Role of Phosphorylated GRTH/DDX25 in Round Spermatid Differentiation and Acrosome Biogenesis during Spermiogenesis
Raghuveer Kavarthapu, Rajakumar Anbazhagan, Soumitra Pal, Maria L. Dufau
Int J Mol Sci. 2023 Feb; 24(4): 3127. Published online 2023 Feb 4. doi: 10.3390/ijms24043127
PMCID:
PMC9962311
ArticlePDF–10M
2.
Blockade of GRTH/DDX25 Phosphorylation by Cyclic Peptides Provides an Avenue for Developing a Nonhormonal Male Contraceptive
Murugananthkumar Raju, Raghuveer Kavarthapu, Rajakumar Anbazhagan, Sergio A. Hassan, Maria L. Dufau
J Med Chem. Author manuscript; available in PMC 2022 Sep 6.
Published in final edited form as: J Med Chem. 2021 Oct 14; 64(19): 14715–14727. Published online 2021 Oct 2. doi: 10.1021/acs.jmedchem.1c01201
PMCID:
PMC9446413
ArticlePDF–2.1M
3.
Chromatoid Bodies in the Regulation of Spermatogenesis: Novel Role of GRTH
Rajakumar Anbazhagan, Raghuveer Kavarthapu, Maria L. Dufau
Cells. 2022 Feb; 11(4): 613. Published online 2022 Feb 10. doi: 10.3390/cells11040613
PMCID:
PMC8870266
ArticlePDF–2.3M
4.
Role of Phosphorylated Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) in the Regulation of Germ Cell Specific mRNAs in Chromatoid Bodies During Spermatogenesis
Rajakumar Anbazhagan, Raghuveer Kavarthapu, Steven L. Coon, Maria L. Dufau
Front Cell Dev Biol. 2020; 8: 580019. Published online 2020 Dec 23. doi: 10.3389/fcell.2020.580019
PMCID:
PMC7786181
ArticlePDF–2.8M
5.
Linking Phospho-Gonadotropin Regulated Testicular RNA Helicase (GRTH/DDX25) to Histone Ubiquitination and Acetylation Essential for Spermatid Development During Spermiogenesis
Raghuveer Kavarthapu, Rajakumar Anbazhagan, Ashish K. Sharma, Joseph Shiloach, Maria L. Dufau
Front Cell Dev Biol. 2020; 8: 310. Published online 2020 May 15. doi: 10.3389/fcell.2020.00310
PMCID:
PMC7242631
ArticlePDF–3.0M
6.
Targeted knock-in mice with a human mutation in GRTH/DDX25 reveals the essential role of phosphorylated GRTH in spermatid development during spermatogenesis
Raghuveer Kavarthapu, Rajakumar Anbazhagan, Murugananthkumar Raju, Chon-Hwa Tsai Morris, James Pickel, Maria L Dufau
Hum Mol Genet. 2019 Aug 1; 28(15): 2561–2572. Published online 2019 Apr 22. doi: 10.1093/hmg/ddz079
PMCID:
PMC6644162
ArticlePDF–38M
7.
Characterization of the Phosphorylation Site of GRTH/DDX25 and Protein Kinase A Binding Interface Provides Structural Basis for the Design of a Non-Hormonal Male Contraceptive
Murugananthkumar Raju, Sergio A. Hassan, Raghuveer Kavarthapu, Rajakumar Anbazhagan, Maria L. Dufau
Sci Rep. 2019; 9: 6705. Published online 2019 Apr 30. doi: 10.1038/s41598-019-42857-9
PMCID:
PMC6491591
ArticlePDF–1.7M
8.
Germ Cell Nuclear Factor (GCNF/RTR) Regulates Transcription of Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) in Testicular Germ Cells—The Androgen Connection
Raghuveer Kavarthapu, Maria L. Dufau
Mol Endocrinol. 2015 Dec; 29(12): 1792–1804. Published online 2015 Oct 20. doi: 10.1210/me.2015-1198
PMCID:
PMC4664233
Article
9.
A 5′-Flanking Region of Gonadotropin-Regulated Testicular RNA Helicase (GRTH/DDX25) Gene Directs Its Cell-Specific Androgen-Regulated Gene Expression in Testicular Germ Cells
Raghuveer Kavarthapu, Chon-Hwa Tsai-Morris, Masato Fukushima, James Pickel, Maria L. Dufau
Endocrinology. 2013 Jun; 154(6): 2200–2207. Published online 2013 Apr 1. doi: 10.1210/en.2012-2230
PMCID:
PMC3740490
Article
10.
Androgen-Induced Activation of Gonadotropin-Regulated Testicular RNA Helicase (GRTH/Ddx25) Transcription: Essential Role of a Nonclassical Androgen Response Element Half-Site
Joaquin Villar, Chon-Hwa Tsai-Morris, Lisheng Dai, Maria L. Dufau
Mol Cell Biol. 2012 Apr; 32(8): 1566–1580. doi: 10.1128/MCB.06002-11
PMCID:
PMC3318589
ArticlePDF–3.9M
11.
Role of Gonadotropin Regulated Testicular RNA Helicase (GRTH/DDX25) on Polysomal Associated mRNAs in Mouse Testis
Chon-Hwa Tsai-Morris, Hisashi Sato, Ravi Gutti, Maria L. Dufau
PLoS One. 2012; 7(3): e32470. Published online 2012 Mar 30. doi: 10.1371/journal.pone.0032470
PMCID:
PMC3316541
ArticlePDF–1.0M
12.
Testis-specific miRNA-469 Up-regulated in Gonadotropin-regulated Testicular RNA Helicase (GRTH/DDX25)-null Mice Silences Transition Protein 2 and Protamine 2 Messages at Sites within Coding Region: IMPLICATIONS OF ITS ROLE IN GERM CELL DEVELOPMENT
Lisheng Dai, Chon-Hwa Tsai-Morris, Hisashi Sato, Joaquin Villar, Jung-Hoon Kang, Jiabao Zhang, Maria L. Dufau
J Biol Chem. 2011 Dec 30; 286(52): 44306–44318. Published online 2011 Nov 15. doi: 10.1074/jbc.M111.282756
PMCID:
PMC3248001
ArticlePDF–2.7M
13.
Gonadotropin-Regulated Testicular RNA helicase (GRTH/Ddx25) a Multifunctional Protein Essential for Spermatogenesis
Chon-Hwa Tsai-Morris, Yi. Sheng, Ravi. Gutti, Pei-Zhong Tang, Maria. L. Dufau
J Androl. Author manuscript; available in PMC 2011 Dec 25.
Published in final edited form as: J Androl. 2010 Jan-Feb; 31(1): 45–52. Published online 2009 Oct 29. doi: 10.2164/jandrol.109.008219
PMCID:
PMC3245878
ArticlePDF–1.6M
14.
Gonadotropin-regulated Testicular RNA Helicase (GRTH/DDX25), a Negative Regulator of Luteinizing/Chorionic Gonadotropin Hormone-induced Steroidogenesis in Leydig Cells: CENTRAL ROLE OF STEROIDOGENIC ACUTE REGULATORY PROTEIN (StAR)
Masato Fukushima, Joaquin Villar, Chon-Hwa Tsai-Morris, Maria L. Dufau
J Biol Chem. 2011 Aug 26; 286(34): 29932–29940. Published online 2011 Jun 30. doi: 10.1074/jbc.M111.236083
PMCID:
PMC3191034
ArticlePDF–1.9M
15.
Relevance of Gonadotropin-Regulated Testicular RNA helicase (GRTH/DDX25) in the Structural Integrity of the Chromatoid Body During Spermatogenesis
Hisashi Sato, Chon-Hwa Tsai-Morris, Maria L. Dufau
Biochim Biophys Acta. Author manuscript; available in PMC 2011 May 1.
Published in final edited form as: Biochim Biophys Acta. 2010 May; 1803(5): 534–543. Published online 2010 Feb 20. doi: 10.1016/j.bbamcr.2010.02.004
PMCID:
PMC2856730
ArticlePDF–2.7M
16.
Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis
Chon-Hwa Tsai-Morris, Yi Sheng, Eric Lee, Ke-Jian Lei, Maria L. Dufau
Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17): 6373–6378. Published online 2004 Apr 19. doi: 10.1073/pnas.0401855101
PMCID:
PMC404052
ArticlePDF–912K
17.
miRNA Expression Profiles of Mouse Round Spermatids in GRTH/DDX25-Mediated Spermiogenesis: mRNA–miRNA Network Analysis
Rajakumar Anbazhagan, Raghuveer Kavarthapu, Ryan Dale, Kiersten Campbell, Fabio R. Faucz, Maria L. Dufau
Cells. 2023 Mar; 12(5): 756. Published online 2023 Feb 27. doi: 10.3390/cells12050756
PMCID:
PMC10001410
ArticlePDF–1.9M
18.
Gonadotropin-regulated Testicular Helicase (DDX25), an Essential Regulator of Spermatogenesis, Prevents Testicular Germ Cell Apoptosis
Ravi K. Gutti, Chon-Hwa Tsai-Morris, Maria L. Dufau
J Biol Chem. 2008 Jun 20; 283(25): 17055–17064. doi: 10.1074/jbc.M708449200
PMCID:
PMC2427358
ArticlePDF–667K
19.
Phenotypic variability in patients with generalised resistance to thyroid hormone.
J Pohlenz, S Wirth, A Winterpacht, H Wemme, B Zabel, W Schönberger
J Med Genet. 1995 May; 32(5): 393–395. doi: 10.1136/jmg.32.5.393
PMCID:
PMC1050437
SummaryPage BrowsePDF–477K
20.
Identical mutations in unrelated families with generalized resistance to thyroid hormone occur in cytosine-guanine-rich areas of the thyroid hormone receptor beta gene. Analysis of 15 families.
R E Weiss, M Weinberg, S Refetoff
J Clin Invest. 1993 Jun; 91(6): 2408–2415. doi: 10.1172/JCI116474
PMCID:
PMC443299
SummaryPage BrowsePDF–1.6M

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Filter your results:

Find related data

Recent activity

Clear Turn Off Turn On

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
You are here: NCBI > Literature > PubMed Central (PMC)
Support Center