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Items: 19

Select item 66312571.

A Single Site Population Study to Investigate CYP2D6 Phenotype of Patients with Persistent Non-Malignant Pain

Helen Radford, Karen H. Simpson, Suzanne Rogerson, Mark I. Johnson

Medicina (Kaunas) 2019 Jun; 55(6): 220. Published online 2019 May 28. doi: 10.3390/medicina55060220

PMCID:: PMC6631257

Abstract Article PDF–2.2M

Select item 49166472.

Nicotine Increases Codeine Analgesia Through the Induction of Brain CYP2D and Central Activation of Codeine to Morphine

Douglas M McMillan, Rachel F Tyndale

Neuropsychopharmacology. 2015 Jun; 40(7): 1804–1812. Prepublished online 2015 Jan 29. Published online 2015 Feb 18. doi: 10.1038/npp.2015.32

PMCID:: PMC4916647

Abstract Article PDF–595K

Select item 37264893.

A Clinical Tool for Reducing Central Nervous System Depression among Neonates Exposed to Codeine through Breast Milk

Lauren E. Kelly, Shahnaz A. Chaudhry, Michael J. Rieder, Geert ‘t Jong, Myla E. Moretti, Andrea Lausman, Colin Ross, Howard Berger, Bruce Carleton, Michael R. Hayden, Parvaz Madadi, Gideon Koren

PLoS One. 2013; 8(7): e70073. Published online 2013 Jul 29. doi: 10.1371/journal.pone.0070073

PMCID:: PMC3726489

Abstract Article PDF–174K

Select item 19525514.

Safety of codeine during breastfeeding: Fatal morphine poisoning in the breastfed neonate of a mother prescribed codeine

Parvaz Madadi, Gideon Koren, James Cairns, David Chitayat, Andrea Gaedigk, J. Steven Leeder, Ronni Teitelbaum, Tatyana Karaskov, Katarina Aleksa

Can Fam Physician. 2007 Jan; 53(1): 33–35.

PMCID:: PMC1952551

Abstract Article PDF–158K

Select item 98722185.

Urinary Pharmacokinetics of Immediate and Controlled Release Oxycodone and its Phase I and II Metabolites Using LC–MS-MS

Michael T Truver, Gerd Jakobsson, Maria D Chermà, Madeleine J Swortwood, Henrik Gréen, Robert Kronstrand

J Anal Toxicol. 2022 Nov; 46(9): 1025–1031. Published online 2021 Dec 18. doi: 10.1093/jat/bkab123

PMCID:: PMC9872218

Abstract Article PDF–628K

Select item 29359976.

The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone

CF Samer, Y Daali, M Wagner, G Hopfgartner, CB Eap, MC Rebsamen, MF Rossier, D Hochstrasser, P Dayer, JA Desmeules

Br J Pharmacol. 2010 Jun; 160(4): 907–918. doi: 10.1111/j.1476-5381.2010.00673.x

PMCID:: PMC2935997

Abstract Article PDF–857K

Select item 29359987.

Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety

CF Samer, Y Daali, M Wagner, G Hopfgartner, CB Eap, MC Rebsamen, MF Rossier, D Hochstrasser, P Dayer, JA Desmeules

Br J Pharmacol. 2010 Jun; 160(4): 919–930. doi: 10.1111/j.1476-5381.2010.00709.x

PMCID:: PMC2935998

Abstract Article PDF–350K

Select item 32491958.

Do CYP2D6 genotypes reflect oxycodone requirements for cancer patients treated for cancer pain? A cross-sectional multicentre study

Trine Naalsund Andreassen, Ingrid Eftedal, Pål Klepstad, Andrew Davies, Kristin Bjordal, Staffan Lundström, Stein Kaasa, Ola Dale

Eur J Clin Pharmacol. 2012; 68(1): 55–64. Published online 2011 Jul 7. doi: 10.1007/s00228-011-1093-5

PMCID:: PMC3249195

Abstract Article PDF–263K

Select item 32899639.

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guidelines for Codeine Therapy in the Context of Cytochrome P450 2D6 (CYP2D6) Genotype

KR Crews, A Gaedigk, HM Dunnenberger, TE Klein, DD Shen, JT Callaghan, ED Kharasch, TC Skaar

Clin Pharmacol Ther. 2012 Feb; 91(2): 321–326. Published online 2011 Dec 28. doi: 10.1038/clpt.2011.287

PMCID:: PMC3289963

Abstract Article PDF–151K

Select item 361066210.

CYP2D6 Genotype Dependent Oxycodone Metabolism in Postoperative Patients

Ulrike M. Stamer, Lan Zhang, Malte Book, Lutz E. Lehmann, Frank Stuber, Frank Musshoff

PLoS One. 2013; 8(3): e60239. Published online 2013 Mar 28. doi: 10.1371/journal.pone.0060239

PMCID:: PMC3610662

Abstract Article PDF–256K

Select item 366320611.

Applications of CYP450 Testing in the Clinical Setting

C. F. Samer, K. Ing Lorenzini, V. Rollason, Y. Daali, J. A. Desmeules

Mol Diagn Ther. 2013; 17(3): 165–184. Published online 2013 Apr 16. doi: 10.1007/s40291-013-0028-5

PMCID:: PMC3663206

Abstract Article PDF–1.0M

Select item 376295412.

Cytochrome P450 2D6 Polymorphisms and Predicted Opioid Metabolism in African-American Children with Sickle Cell Disease

Marianne McPherson Yee, Cassandra Josephson, Charles E. Hill, Rosiland Harrington, Marta-Inés Castillejo, Ruan Ramjit, Ifeyinwa Osunkwo

J Pediatr Hematol Oncol. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: J Pediatr Hematol Oncol. 2013 Oct; 35(7): e301–e305. doi: 10.1097/MPH.0b013e31828e52d2

PMCID:: PMC3762954

Abstract Article PDF–99K

Select item 492507313.

Pharmacogenetics for Safe Codeine Use in Sickle Cell Disease

Roseann S. Gammal, Kristine R. Crews, Cyrine E. Haidar, James M. Hoffman, Donald K. Baker, Patricia J. Barker, Jeremie H. Estepp, Deqing Pei, Ulrich Broeckel, Winfred Wang, Mitchell J. Weiss, Mary V. Relling, Jane Hankins

Pediatrics. 2016 Jul; 138(1): e20153479. doi: 10.1542/peds.2015-3479

PMCID:: PMC4925073

Abstract Article PDF–2.0M

Select item 555852914.

CYP2D6 pharmacogenetic and oxycodone pharmacokinetic association study in pediatric surgical patients

Rajiv Balyan, Marc Mecoli, Raja Venkatasubramanian, Vidya Chidambaran, Nichole Kamos, Smokey Clay, David L Moore, Jagroop Mavi, Chris D Glover, Peter Szmuk, Alexander Vinks, Senthilkumar Sadhasivam

Pharmacogenomics. 2017 Mar; 18(4): 337–348. Published online 2017 Feb 17. doi: 10.2217/pgs-2016-0183

PMCID:: PMC5558529

Abstract Article PDF–1.6M

Select item 656282915.

Drug–gene and drug–drug interactions associated with tramadol and codeine therapy in the INGENIOUS trial

Cathy R Fulton, Yong Zang, Zeruesenay Desta, Marc B Rosenman, Ann M Holmes, Brian S Decker, Yifei Zhang, John T Callaghan, Victoria M Pratt, Kenneth D Levy, Brandon T Gufford, Paul R Dexter, Todd C Skaar, Michael T Eadon

Pharmacogenomics. 2019 Apr; 20(6): 397–408. Published online 2019 Feb 20. doi: 10.2217/pgs-2018-0205

PMCID:: PMC6562829

Abstract Article PDF–493K

Select item 829517116.

CYP2D6 GENOTYPE AND REDUCED CODEINE ANALGESIC EFFECT IN REAL-WORLD CLINICAL PRACTICE

Daniel Carranza-Leon, Alyson L. Dickson, Andrea Gaedigk, C. Michael Stein, Cecilia P. Chung

Pharmacogenomics J. Author manuscript; available in PMC 2021 Sep 9.

Published in final edited form as: Pharmacogenomics J. 2021 Aug; 21(4): 484–490. Published online 2021 Mar 9. doi: 10.1038/s41397-021-00226-8

PMCID:: PMC8295171

Abstract Article PDF–399K

Select item 852521717.

A Hybrid Implementation-Effectiveness Randomized Trial of CYP2D6 Guided Post-operative Pain Management

Cameron D. Thomas, Hari K. Parvataneni, Chancellor F. Gray, Justin T. Deen, Hernan A. Prieto, Luis F. Pulido, Amanda R. Elsey, Erica N. Elwood, Petr Starostik, Yan Gong, Roger B. Fillingim, Julie A. Johnson, Larisa H. Cavallari

Genet Med. Author manuscript; available in PMC 2021 Oct 19.

Published in final edited form as: Genet Med. 2021 Apr; 23(4): 621–628. Published online 2021 Jan 8. doi: 10.1038/s41436-020-01050-4

PMCID:: PMC8525217

Abstract Article PDF–286K

Select item 857174018.

Impact of CYP2D6 Pharmacogenomic Status on Pain Control Among Opioid‐Treated Oncology Patients

Natalie Reizine, Keith Danahey, Emily Schierer, Ping Liu, Merisa Middlestadt, Jenna Ludwig, Tien M. Truong, Xander M.R. van Wijk, Kiang‐Teck J. Yeo, Monica Malec, Mark J. Ratain, Peter H. O'Donnell

Oncologist. 2021 Nov; 26(11): e2042–e2052. Published online 2021 Sep 19. doi: 10.1002/onco.13953

PMCID:: PMC8571740

Abstract Article PDF–1.4M

Select item 955393519.

Dutch Pharmacogenetics Working Group (DPWG) guideline for the gene–drug interaction between CYP2D6 and opioids (codeine, tramadol and oxycodone)

Maja Matic, Marga Nijenhuis, Bianca Soree, Nienke J. de Boer-Veger, Anne-Marie Buunk, Elisa J. F. Houwink, Hans Mulder, Gerard A. P. J. M. Rongen, Jan van der Weide, Bob Wilffert, Jesse J. Swen, Henk-Jan Guchelaar, Vera H. M. Deneer, Ron H. N. van Schaik

Eur J Hum Genet. 2022 Oct; 30(10): 1105–1113. Published online 2021 Jul 15. doi: 10.1038/s41431-021-00920-y

Correction in:: Eur J Hum Genet. 2022 Oct; 30(10): 1196.

PMCID:: PMC9553935

Abstract Article PDF–652K

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Homo sapiens fragile X mental retardation 1 (FMR1) mRNA, complete cds, alternati...
Homo sapiens fragile X mental retardation 1 (FMR1) mRNA, complete cds, alternatively spliced
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