PMC Articles for MedGen (Select 1720013) - PMC

Select item 113527061.

Overexpression of CCL-20 and CXCL-8 genes enhances tumor escape and resistance to cemiplimab, a programmed cell death protein-1 (PD-1) inhibitor, in patients with locally advanced and metastatic cutaneous squamous cell carcinoma

Vincenzo De Falco, Stefania Napolitano, Renato Franco, Federica Zito Marino, Luigi Formisano, Daniela Esposito, Gabriella Suarato, Rossella Napolitano, Alfonso Esposito, Francesco Caraglia, Maria Cristina Giugliano, Eleonora Cioli, Vincenzo Famiglietti, Roberto Bianco, Giuseppe Argenziano, Andrea Ronchi, Davide Ciardiello, Valerio Nardone, Emma D’Ippolito, Sara Del Tufo, Fortunato Ciardiello, Teresa Troiani

Oncoimmunology. 2024; 13(1): 2388315. Published online 2024 Aug 26. doi: 10.1080/2162402X.2024.2388315

PMCID:: PMC11352706

Abstract Article PDF–4.7M

Select item 100733122.

Extrachromosomal DNA Amplification Contributes to Small Cell Lung Cancer Heterogeneity and is Associated with Worse Outcomes

Lőrinc Sándor Pongor, Christopher W. Schultz, Lorenzo Rinaldi, Darawalee Wangsa, Christophe E. Redon, Nobuyuki Takahashi, Gavriel Fialkoff, Parth Desai, Yang Zhang, Sandra Burkett, Nadav Hermoni, Noa Vilk, Jenia Gutin, Gergely Rona, Yongmei Zhao, Samantha Nichols, Rasa Vilimas, Linda Sciuto, Chante Graham, Juan Manuel Caravaca, Sevilay Turan, Tsai-wei Shen, Vinodh N Rajapakse, Rajesh Kumar, Deep Upadhyay, Suresh Kumar, Yoo Sun Kim, Nitin Roper, Bao Tran, Stephen M. Hewitt, David E. Kleiner, Mirit I Aladjem, Nir Friedman, Gordon L. Hager, Yves Pommier, Thomas Ried, Anish Thomas

Cancer Discov. Author manuscript; available in PMC 2023 Oct 3.

Published in final edited form as: Cancer Discov. 2023 Apr 3; 13(4): 928–949. doi: 10.1158/2159-8290.CD-22-0796

PMCID:: PMC10073312

Abstract Article PDF–1.4M

Select item 93653363.

Identification of KRAS^G12C Mutations in Circulating Tumor DNA in Patients With Cancer

Kyaw Z. Thein, Amadeo B. Biter, Kimberly C. Banks, Andrew W. Duda, Jennifer Saam, Jason Roszik, Filip Janku, Ferdinandos Skoulidis, John V. Heymach, Scott Kopetz, Funda Meric-Bernstam, David S. Hong

JCO Precis Oncol. 2022; 6: e2100547. Published online 2022 Jul 21. doi: 10.1200/PO.21.00547

PMCID:: PMC9365336

Abstract Article PDF–806K

Select item 84373564.

Merkel Cell Polyomavirus Infection Induces an Antiviral Innate Immune Response in Human Dermal Fibroblasts

Nathan A. Krump, Ranran Wang, Wei Liu, June F. Yang, Tongcui Ma, Jianxin You

J Virol. 2021 Jul; 95(13): e02211-20. Prepublished online 2021 Apr 21. Published online 2021 Jun 10. doi: 10.1128/JVI.02211-20

PMCID:: PMC8437356

Abstract Article PDF–5.4M

Select item 81375395.

Evasion of Innate Immunity Contributes to Small Cell Lung Cancer Progression and Metastasis

Mingrui Zhu, Yi Huang, Matthew E Bender, Luc Girard, Rahul Kollipara, Buse Eglenen-Polat, Yujiro Naito, Trisha K Savage, Kenneth E Huffman, Shohei Koyama, Atsushi Kumanogoh, John D Minna, Jane E Johnson, Esra A Akbay

Cancer Res. Author manuscript; available in PMC 2021 Oct 1.

Published in final edited form as: Cancer Res. 2021 Apr 1; 81(7): 1813–1826. Published online 2021 Jan 25. doi: 10.1158/0008-5472.CAN-20-2808

PMCID:: PMC8137539

Abstract Article PDF–1.1M

Select item 79597076.

Comprehensive Genomic Profiling of Rare Tumors in China: Routes to Immunotherapy

Shuhang Wang, Yuan Fang, Ning Jiang, Shujun Xing, Qin Li, Rongrong Chen, Xin Yi, Zhiqian Zhang, Ning Li

Front Immunol. 2021; 12: 631483. Published online 2021 Feb 25. doi: 10.3389/fimmu.2021.631483

PMCID:: PMC7959707

Abstract Article PDF–3.2M

Select item 77020757.

PCSK2 expression in neuroendocrine tumors points to a midgut, pulmonary, or pheochromocytoma–paraganglioma origin

Satu Maria Remes, Helena Leijon, Tiina Vesterinen, Johanna Louhimo, Ville Pulkkinen, Sini Ezer, Juha Kere, Caj Haglund, Johanna Arola

APMIS. 2020 Nov; 128(11): 563–572. Published online 2020 Sep 28. doi: 10.1111/apm.13071

PMCID:: PMC7702075

Abstract Article PDF–1.7M

Select item 74703738.

High-resolution analysis of Merkel Cell Polyomavirus in Merkel Cell Carcinoma reveals distinct integration patterns and suggests NHEJ and MMBIR as underlying mechanisms

Manja Czech-Sioli, Thomas Günther, Marlin Therre, Michael Spohn, Daniela Indenbirken, Juliane Theiss, Sabine Riethdorf, Minyue Qi, Malik Alawi, Corinna Wülbeck, Irene Fernandez-Cuesta, Franziska Esmek, Jürgen C. Becker, Adam Grundhoff, Nicole Fischer

PLoS Pathog. 2020 Aug; 16(8): e1008562. Published online 2020 Aug 24. doi: 10.1371/journal.ppat.1008562

PMCID:: PMC7470373

Abstract Article PDF–5.2M

Select item 72883739.

Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma

Pavlos Msaouel, Gabriel G. Malouf, Xiaoping Su, Hui Yao, Durga N. Tripathi, Melinda Soeung, Jianjun Gao, Priya Rao, Cristian Coarfa, Chad J. Creighton, Jean-Philippe Bertocchio, Selvi Kunnimalaiyaan, Asha S. Multani, Jorge Blando, Rong He, Daniel D. Shapiro, Luigi Perelli, Sanjana Srinivasan, Federica Carbone, Patrick G. Pilié, Menuka Karki, Riyad N.H. Seervai, Bujamin H. Vokshi, Dolores Lopez-Terrada, Emily H. Cheng, Ximing Tang, Wei Lu, Ignacio I. Wistuba, Timothy C. Thompson, Irwin Davidson, Virginia Giuliani, Katharina Schlacher, Alessandro Carugo, Timothy P. Heffernan, Padmanee Sharma, Jose A. Karam, Christopher G. Wood, Cheryl L. Walker, Giannicola Genovese, Nizar M. Tannir

Cancer Cell. Author manuscript; available in PMC 2021 May 11.

Published in final edited form as: Cancer Cell. 2020 May 11; 37(5): 720–734.e13. Published online 2020 Apr 30. doi: 10.1016/j.ccell.2020.04.002

PMCID:: PMC7288373

Abstract Article PDF–3.2M

Select item 710883110.

Kaposi’s Sarcoma-Associated Herpesvirus Infection Induces the Expression of Neuroendocrine Genes in Endothelial Cells

Mohanan Valiya Veettil, Gayathri Krishna, Arunava Roy, Anandita Ghosh, Dipanjan Dutta, Binod Kumar, Sayan Chakraborty, Thoppil Raveendran Anju, Neelam Sharma-Walia, Bala Chandran

J Virol. 2020 Apr; 94(8): e01692-19. Prepublished online 2020 Jan 22. Published online 2020 Mar 31. doi: 10.1128/JVI.01692-19

PMCID:: PMC7108831

Abstract Article PDF–3.4M

Select item 650694411.

Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression

Soyoung Choi, Dunrui Wang, Xiang Chen, Laura H. Tang, Akanksha Verma, Zhengming Chen, Bu Jung Kim, Leigh Selesner, Kenneth Robzyk, George Zhang, Sharon Pang, Teng Han, Chang S. Chan, Thomas J. Fahey, III, Olivier Elemento, Yi-Chieh Nancy Du

Mol Cancer. 2019; 18: 92. Published online 2019 May 9. doi: 10.1186/s12943-019-1018-y

PMCID:: PMC6506944

Abstract Article PDF–2.3M

Select item 581593112.

Merkel cell carcinoma patients presenting without a primary lesion have elevated markers of immunity, higher tumor mutation burden and improved survival

Natalie Vandeven, Christopher W. Lewis, Vladimir Makarov, Nadeem Riaz, Kelly G. Paulson, Daniel Hippe, Amy Bestick, Ryan Doumani, Tessa Marx, Seesha Takagishi, Timothy A. Chan, Jaehyuk Choi, Paul Nghiem

Clin Cancer Res. Author manuscript; available in PMC 2019 Feb 15.

Published in final edited form as: Clin Cancer Res. 2018 Feb 15; 24(4): 963–971. Published online 2017 Dec 15. doi: 10.1158/1078-0432.CCR-17-1678

PMCID:: PMC5815931

Abstract Article PDF–449K

Select item 517543813.

Medullary Thyroid Carcinoma Associated with Germline RET^K666N Mutation

Jian Yu Xu, Elizabeth G. Grubbs, Steven G. Waguespack, Camilo Jimenez, Robert F. Gagel, Julie A. Sosa, Rena V. Sellin, Ramona Dadu, Mimi I. Hu, Chardria S. Trotter, Michelle Jackson, Thereasa A. Rich, Samuel M. Hyde, Steven I. Sherman, Gilbert J. Cote

Thyroid. 2016 Dec 1; 26(12): 1744–1751. Published online 2016 Dec 1. doi: 10.1089/thy.2016.0374

PMCID:: PMC5175438

Abstract Article PDF–276K

Select item 391250914.

Activation of PI3K signaling in Merkel cell carcinoma

Valentina Nardi, Young Chul Song, Juan A. Santamaria-Barria, Arjola K. Cosper, Quynh Lam, Anthony C. Faber, Genevieve M. Boland, Beow Y. Yeap, Kristin Bergethon, Vanessa L. Scialabba, Hensin Tsao, Jeffrey Settleman, David P. Ryan, Darrell R. Borger, Atul Bhan, Mai P. Hoang, Anthony J. Iafrate, James C. Cusack, Jeffrey A. Engelman, Dora Dias-Santagata

Clin Cancer Res. Author manuscript; available in PMC 2014 Feb 4.

Published in final edited form as: Clin Cancer Res. 2012 Mar 1; 18(5): 1227–1236. Published online 2012 Jan 18. doi: 10.1158/1078-0432.CCR-11-2308

PMCID:: PMC3912509

Abstract Article PDF–1.1M

Select item 332883715.

Multiple endocrine neoplasia type 2: achievements and current challenges

Andreas Machens, Henning Dralle

Clinics (Sao Paulo) 2012 Apr; 67(Suppl 1): 113–118. doi: 10.6061/clinics/2012(Sup01)19

PMCID:: PMC3328837

Abstract Article PDF–675K

Select item 289363216.

Hybrid Model Integrating Immunohistochemistry and Expression Profiling for the Classification of Carcinomas of Unknown Primary Site

Barbara A. Centeno, Gregory Bloom, Dung-Tsa Chen, Zhihua Chen, Mike Gruidl, Aejaz Nasir, Timothy Y. Yeatman

J Mol Diagn. 2010 Jul; 12(4): 476–486. doi: 10.2353/jmoldx.2010.090197

PMCID:: PMC2893632

Abstract Article PDF–319K

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