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Items: 1 to 20 of 129

1.
Randomised Phase II Trial of Irinotecan/Temozolomide (I/T) with Temsirolimus (TEM) or Dinutuximab (DIN) in Children with Refractory or Relapsed Neuroblastoma: A Report from The Children’s Oncology Group (COG)
Rajen Mody, Arlene Naranjo, Collin Van Ryn, Alice L. Yu, Wendy B. London, Barry L. Shulkin, Marguerite T. Parisi, Sabah-E-Noor Servaes, Mitchell B. Diccianni, Paul M. Sondel, John M. Maris, Julie R. Park, Rochelle Bagatell
Lancet Oncol. Author manuscript; available in PMC 2017 Jul 26.
Published in final edited form as: Lancet Oncol. 2017 Jul; 18(7): 946–957. Published online 2017 May 23. doi: 10.1016/S1470-2045(17)30355-8
PMCID:
PMC5527694
AbstractArticlePDF–608K
2.
Gene Editing of CCR5 in Autologous CD4 T Cells of Persons Infected with HIV
Pablo Tebas, David Stein, Winson W. Tang, Ian Frank, Shelley Q. Wang, Gary Lee, S. Kaye Spratt, Richard T. Surosky, Martin A. Giedlin, Geoff Nichol, Michael C. Holmes, Philip D. Gregory, Dale G. Ando, Michael Kalos, Ronald G. Collman, Gwendolyn Binder-Scholl, Gabriela Plesa, Wei-Ting Hwang, Bruce L. Levine, Carl H. June
N Engl J Med. Author manuscript; available in PMC 2014 Sep 6.
Published in final edited form as: N Engl J Med. 2014 Mar 6; 370(10): 901–910. doi: 10.1056/NEJMoa1300662
PMCID:
PMC4084652
AbstractArticlePDF–1.3M
3.
Distribution of CYP2D6 Alleles and Phenotypes in the Brazilian Population
Deise C. Friedrich, Júlia P. Genro, Vinicius A. Sortica, Guilherme Suarez-Kurtz, Maria Elizabete de Moraes, Sergio D. J. Pena, Ândrea K. Ribeiro dos Santos, Marco A. Romano-Silva, Mara H. Hutz
PLoS One. 2014; 9(10): e110691. Published online 2014 Oct 20. doi: 10.1371/journal.pone.0110691
PMCID:
PMC4203818
AbstractArticlePDF–217K
4.
Biological significance of HLA locus matching in unrelated donor bone marrow transplantation
Yasuo Morishima, Koichi Kashiwase, Keitaro Matsuo, Fumihiro Azuma, Satoko Morishima, Makoto Onizuka, Toshio Yabe, Makoto Murata, Noriko Doki, Tetsuya Eto, Takehiko Mori, Koichi Miyamura, Hiroshi Sao, Tatsuo Ichinohe, Hiroo Saji, Shunichi Kato, Yoshiko Atsuta, Keisei Kawa, Yoshihisa Kodera, Takehiko Sasazuki
Blood. 2015 Feb 12; 125(7): 1189–1197. Prepublished online 2014 Dec 17. doi: 10.1182/blood-2014-10-604785
PMCID:
PMC4326776
AbstractArticle
5.
Predicting the Impact of Adverse Events and Treatment Duration on Medical Resource Utilization-Related Costs in Hepatitis C Genotype 1 Treatment-Naïve Patients Receiving Antiviral Therapy
Essè Ifèbi Hervé Akpo, Karin Cerri, Joris Kleintjens
Pharmacoeconomics. 2015; 33(4): 409–422. Published online 2015 Jan 11. doi: 10.1007/s40273-014-0249-4
PMCID:
PMC4381112
AbstractArticlePDF–372K
6.
Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia
Sabine Cerny-Reiterer, Anja Rabenhorst, Gabriele Stefanzl, Susanne Herndlhofer, Gregor Hoermann, Leonhard Müllauer, Sigrid Baumgartner, Christine Beham-Schmid, Wolfgang R Sperr, Christine Mannhalter, Heinz Sill, Werner Linkesch, Michel Arock, Karin Hartmann, Peter Valent
Oncotarget. 2015 Feb; 6(5): 3071–3084. Published online 2014 Dec 26. doi: 10.18632/oncotarget.3074
PMCID:
PMC4413638
AbstractArticlePDF–3.1M
7.
Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association
Véronique L. Roger, Alan S. Go, Donald M. Lloyd-Jones, Robert J. Adams, Jarett D. Berry, Todd M. Brown, Mercedes R. Carnethon, Shifan Dai, Giovanni de Simone, Earl S. Ford, Caroline S. Fox, Heather J. Fullerton, Cathleen Gillespie, Kurt J. Greenlund, Susan M. Hailpern, John A. Heit, P. Michael Ho, Virginia J. Howard, Brett M. Kissela, Steven J. Kittner, Daniel T. Lackland, Judith H. Lichtman, Lynda D. Lisabeth, Diane M. Makuc, Gregory M. Marcus, Ariane Marelli, David B. Matchar, Mary M. McDermott, James B. Meigs, Claudia S. Moy, Dariush Mozaffarian, Michael E. Mussolino, Graham Nichol, Nina P. Paynter, Wayne D. Rosamond, Paul D. Sorlie, Randall S. Stafford, Tanya N. Turan, Melanie B. Turner, Nathan D. Wong, Judith Wylie-Rosett
Circulation. Author manuscript; available in PMC 2015 May 4.
Published in final edited form as: Circulation. 2011 Feb 1; 123(4): e18–e209. Published online 2010 Dec 15. doi: 10.1161/CIR.0b013e3182009701
Correction in:
volume 124 on page e426
PMCID:
PMC4418670
AbstractArticlePDF–18M
8.
Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors
E. M. Dunbar, B. S. Coats, A. L. Shroads, T. Langaee, A. Lew, J. R. Forder, J. J. Shuster, D. A. Wagner, P. W. Stacpoole
Invest New Drugs. Author manuscript; available in PMC 2015 Jun 4.
Published in final edited form as: Invest New Drugs. 2014 Jun; 32(3): 452–464. Published online 2013 Dec 3. doi: 10.1007/s10637-013-0047-4
PMCID:
PMC4455946
AbstractArticlePDF–993K
9.
Reproductive Health Issues for Adults with a Common Genomic Disorder: 22q11.2 Deletion Syndrome
Chrystal Chan, Gregory Costain, Lucas Ogura, Candice K. Silversides, Eva W.C. Chow, Anne S. Bassett
J Genet Couns. Author manuscript; available in PMC 2015 Oct 1.
Published in final edited form as: J Genet Couns. 2015 Oct; 24(5): 810–821. Published online 2015 Jan 13. doi: 10.1007/s10897-014-9811-7
PMCID:
PMC4567324
AbstractArticlePDF–365K
10.
Sphingosine Kinase 1 Protects Hepatocytes from Lipotoxicity via Down-regulation of IRE1α Protein Expression
Yanfei Qi, Wei Wang, Jinbiao Chen, Lan Dai, Dominik Kaczorowski, Xin Gao, Pu Xia
J Biol Chem. 2015 Sep 18; 290(38): 23282–23290. Published online 2015 Aug 3. doi: 10.1074/jbc.M115.677542
PMCID:
PMC4645625
AbstractArticlePDF–1.5M
11.
Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial
Eric W F W Alton, David K Armstrong, Deborah Ashby, Katie J Bayfield, Diana Bilton, Emily V Bloomfield, A Christopher Boyd, June Brand, Ruaridh Buchan, Roberto Calcedo, Paula Carvelli, Mario Chan, Seng H Cheng, D David S Collie, Steve Cunningham, Heather E Davidson, Gwyneth Davies, Jane C Davies, Lee A Davies, Maria H Dewar, Ann Doherty, Jackie Donovan, Natalie S Dwyer, Hala I Elgmati, Rosanna F Featherstone, Jemyr Gavino, Sabrina Gea-Sorli, Duncan M Geddes, James S R Gibson, Deborah R Gill, Andrew P Greening, Uta Griesenbach, David M Hansell, Katharine Harman, Tracy E Higgins, Samantha L Hodges, Stephen C Hyde, Laura Hyndman, J Alastair Innes, Joseph Jacob, Nancy Jones, Brian F Keogh, Maria P Limberis, Paul Lloyd-Evans, Alan W Maclean, Michelle C Manvell, Dominique McCormick, Michael McGovern, Gerry McLachlan, Cuixiang Meng, M Angeles Montero, Hazel Milligan, Laura J Moyce, Gordon D Murray, Andrew G Nicholson, Tina Osadolor, Javier Parra-Leiton, David J Porteous, Ian A Pringle, Emma K Punch, Kamila M Pytel, Alexandra L Quittner, Gina Rivellini, Clare J Saunders, Ronald K Scheule, Sarah Sheard, Nicholas J Simmonds, Keith Smith, Stephen N Smith, Najwa Soussi, Samia Soussi, Emma J Spearing, Barbara J Stevenson, Stephanie G Sumner-Jones, Minna Turkkila, Rosa P Ureta, Michael D Waller, Marguerite Y Wasowicz, James M Wilson, Paul Wolstenholme-Hogg, UK Cystic Fibrosis Gene Therapy Consortium
Lancet Respir Med. 2015 Sep; 3(9): 684–691. doi: 10.1016/S2213-2600(15)00245-3
Correction in:
Lancet Respir Med. 2015 Sep; 3(9): e33.
PMCID:
PMC4673100
AbstractArticle
12.
Consistent gene expression profiles in MexTAg transgenic mouse and wild type mouse asbestos-induced mesothelioma
Cleo Robinson, Ian M. Dick, Michael J. Wise, Andrew Holloway, Dileepa Diyagama, Bruce W. S. Robinson, Jenette Creaney, Richard A. Lake
BMC Cancer. 2015; 15: 983. Published online 2015 Dec 18. doi: 10.1186/s12885-015-1953-y
PMCID:
PMC4683914
AbstractArticlePDF–3.0M
13.
Pioglitazone, a PPARγ agonist, attenuates PDGF-induced vascular smooth muscle cell proliferation through AMPK-dependent and AMPK-independent inhibition of mTOR/p70S6K and ERK signaling
Islam Osman, Lakshman Segar
Biochem Pharmacol. Author manuscript; available in PMC 2017 Feb 1.
Published in final edited form as: Biochem Pharmacol. 2016 Feb 1; 101: 54–70. Published online 2015 Nov 28. doi: 10.1016/j.bcp.2015.11.026
PMCID:
PMC4753090
AbstractArticlePDF–3.4M
14.
Combination of International Scoring System 3, High Lactate Dehydrogenase, and t(4;14) and/or del(17p) Identifies Patients With Multiple Myeloma (MM) Treated With Front-Line Autologous Stem-Cell Transplantation at High Risk of Early MM Progression–Related Death
Philippe Moreau, Michele Cavo, Pieter Sonneveld, Laura Rosinol, Michel Attal, Annalisa Pezzi, Hartmut Goldschmidt, Juan Jose Lahuerta, Gerald Marit, Antonio Palumbo, Bronno van der Holt, Joan Bladé, Maria Teresa Petrucci, Kai Neben, Jesus san Miguel, Francesca Patriarca, Henk Lokhorst, Elena Zamagni, Cyrille Hulin, Norma Gutierrez, Thierry Facon, Denis Caillot, Lotfi Benboubker, Jean-Luc Harousseau, Xavier Leleu, Hervé Avet-Loiseau, Jean-Yves Mary
J Clin Oncol. 2014 Jul 10; 32(20): 2173–2180. Published online 2014 Jun 2. doi: 10.1200/JCO.2013.53.0329
PMCID:
PMC4879712
AbstractArticlePDF–167K
15.
Pharmacogenetics for Safe Codeine Use in Sickle Cell Disease
Roseann S. Gammal, Kristine R. Crews, Cyrine E. Haidar, James M. Hoffman, Donald K. Baker, Patricia J. Barker, Jeremie H. Estepp, Deqing Pei, Ulrich Broeckel, Winfred Wang, Mitchell J. Weiss, Mary V. Relling, Jane Hankins
Pediatrics. 2016 Jul; 138(1): e20153479. doi: 10.1542/peds.2015-3479
PMCID:
PMC4925073
AbstractArticlePDF–2.0M
16.
DL-ADR: a novel deep learning model for classifying genomic variants into adverse drug reactions
Zhaohui Liang, Jimmy Xiangji Huang, Xing Zeng, Gang Zhang
BMC Med Genomics. 2016; 9(Suppl 2): 48. Published online 2016 Aug 10. doi: 10.1186/s12920-016-0207-4
PMCID:
PMC4980789
AbstractArticlePDF–1.2M
17.
Single-dose infliximab in hepatitis C genotype 1 treatmentnaive patients with high serum levels of tumour necrosis factor-alpha does not influence the efficacy of pegylated interferon alpha-2b/ribavirin therapy
Curtis Cooper, Stephen Shafran, Susan Greenbloom, Robert Enns, John Farley, Nir Hilzenrat, Kurt Williams, Magdy Elkashab, Nabil Abadir, Manuela Neuman
Can J Gastroenterol Hepatol. 2014 Jan; 28(1): 35–40. doi: 10.1155/2014/367131
PMCID:
PMC4071902
AbstractArticlePDF–1.3M
18.
High expression of CPNE3 predicts adverse prognosis in acute myeloid leukemia
Lin Fu, Huaping Fu, Jianlin Qiao, Yifan Pang, Keman Xu, Lei Zhou, Qingyun Wu, Zhenyu Li, Xiaoyan Ke, Kailin Xu, Jinlong Shi
Cancer Sci. 2017 Sep; 108(9): 1850–1857. Published online 2017 Aug 20. doi: 10.1111/cas.13311
PMCID:
PMC5581509
AbstractArticlePDF–2.3M
19.
Critical biological parameters modulate affinity as a determinant of function in T-cell receptor gene-modified T-cells
Timothy T. Spear, Yuan Wang, Kendra C. Foley, David C. Murray, Gina M. Scurti, Patricia E. Simms, Elizabeth Garrett-Mayer, Lance M. Hellman, Brian M. Baker, Michael I. Nishimura
Cancer Immunol Immunother. 2017 Nov; 66(11): 1411–1424. Published online 2017 Jun 20. doi: 10.1007/s00262-017-2032-9
PMCID:
PMC5647210
AbstractArticlePDF–2.0M
20.
Lorlatinib in ALK- or ROS1-rearranged non-small cell lung cancer: an international, multicenter, open-label phase 1 trial
Alice T. Shaw, Enriqueta Felip, Todd M. Bauer, Benjamin Besse, Alejandro Navarro, Sophie Postel-Vinay, Justin F. Gainor, Melissa Johnson, Jorg Dietrich, Leonard P. James, Jill S. Clancy, Joseph Chen, Jean-François Martini, Antonello Abbattista, Benjamin J. Solomon
Lancet Oncol. Author manuscript; available in PMC 2018 Dec 1.
Published in final edited form as: Lancet Oncol. 2017 Dec; 18(12): 1590–1599. Published online 2017 Oct 23. doi: 10.1016/S1470-2045(17)30680-0
PMCID:
PMC5777233
AbstractArticlePDF–712K

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