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Items: 1 to 20 of 410

1.
mTOR Inhibition Promotes TTF1-Dependent Redifferentiation and Restores Iodine Uptake in Thyroid Carcinoma Cell Lines
Theo S. Plantinga, Bas Heinhuis, Danny Gerrits, Mihai G. Netea, Leo A. B. Joosten, Ad R. M. M. Hermus, Wim J. G. Oyen, Rebecca E. Schweppe, Bryan R. Haugen, Otto C. Boerman, Johannes W. A. Smit, Romana T. Netea-Maier
J Clin Endocrinol Metab. 2014 Jul; 99(7): E1368–E1375. Published online 2014 Apr 8. doi: 10.1210/jc.2014-1171
PMCID:
PMC5393487
AbstractArticle
2.
Clinical benefit of a precision medicine based approach for guiding treatment of refractory cancers
Milan Radovich, Patrick J. Kiel, Stacy M. Nance, Erin E. Niland, Megan E. Parsley, Meagan E. Ferguson, Guanglong Jiang, Natraj R. Ammakkanavar, Lawrence H. Einhorn, Liang Cheng, Mehdi Nassiri, Darrell D. Davidson, Daniel A. Rushing, Patrick J. Loehrer, Roberto Pili, Nasser Hanna, J. Thomas Callaghan, Todd C. Skaar, Paul R. Helft, Safi Shahda, Bert H. O’Neil, Bryan P. Schneider
Oncotarget. 2016 Aug 30; 7(35): 56491–56500. Published online 2016 Jul 15. doi: 10.18632/oncotarget.10606
PMCID:
PMC5302930
AbstractArticlePDF–1.5M
3.
A phase 1/2a, dose-escalation, safety, pharmacokinetic, and preliminary efficacy study of intraperitoneal administration of BC-819 (H19-DTA) in subjects with recurrent ovarian/peritoneal cancer
Ofer Lavie, David Edelman, Tally Levy, Ami Fishman, Ayala Hubert, Yakir Segev, Eli Raveh, Michal Gilon, Avraham Hochberg
Arch Gynecol Obstet. 2017; 295(3): 751–761. Published online 2017 Feb 3. doi: 10.1007/s00404-017-4293-0
PMCID:
PMC5315703
AbstractArticlePDF–632K
4.
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer
Adrian Vallejo, Naiara Perurena, Elisabet Guruceaga, Pawel K. Mazur, Susana Martinez-Canarias, Carolina Zandueta, Karmele Valencia, Andrea Arricibita, Dana Gwinn, Leanne C. Sayles, Chen-Hua Chuang, Laura Guembe, Peter Bailey, David K. Chang, Andrew Biankin, Mariano Ponz-Sarvise, Jesper B. Andersen, Purvesh Khatri, Aline Bozec, E. Alejandro Sweet-Cordero, Julien Sage, Fernando Lecanda, Silve Vicent
Nat Commun. 2017; 8: 14294. Published online 2017 Feb 21. doi: 10.1038/ncomms14294
PMCID:
PMC5321758
AbstractArticlePDF–2.6M
5.
Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions
Pierre Vanden Borre, Alexa B. Schrock, Peter M. Anderson, John C. Morris, III, Andreas M. Heilmann, Oliver Holmes, Kai Wang, Adrienne Johnson, Steven G. Waguespack, Sai‐Hong Ignatius Ou, Saad Khan, Kar‐Ming Fung, Philip J. Stephens, Rachel L. Erlich, Vincent A. Miller, Jeffrey S. Ross, Siraj M. Ali
Oncologist. 2017 Mar; 22(3): 255–263. Published online 2017 Feb 16. doi: 10.1634/theoncologist.2016-0279
PMCID:
PMC5344643
AbstractArticlePDF–706K
6.
Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis
Mehmet Asim Bilen, Kenneth R. Hess, Matthew T. Campbell, Jennifer Wang, Russell R. Broaddus, Jose A. Karam, John F. Ward, Christopher G. Wood, Seungtaek L. Choi, Priya Rao, Miao Zhang, Aung Naing, Rosale General, Diana H. Cauley, Sue-Hwa Lin, Christopher J. Logothetis, Louis L. Pisters, Shi-Ming Tu
Oncotarget. 2016 Dec 27; 7(52): 86280–86289. Published online 2016 Nov 16. doi: 10.18632/oncotarget.13380
PMCID:
PMC5349913
AbstractArticlePDF–3.6M
7.
Drug-dependent functionalization of wild-type and mutant p53 in cisplatin-resistant human ovarian tum3or cells
Michelle Bhatt, Cristina Ivan, Xiaolei Xie, Zahid H. Siddik
Oncotarget. 2017 Feb 14; 8(7): 10905–10918. Published online 2016 Dec 26. doi: 10.18632/oncotarget.14228
PMCID:
PMC5355233
AbstractArticlePDF–3.0M
8.
Exosomes as mediators of platinum resistance in ovarian cancer
Jennifer Crow, Safinur Atay, Samagya Banskota, Brittany Artale, Sarah Schmitt, Andrew K Godwin
Oncotarget. 2017 Feb 14; 8(7): 11917–11936. Published online 2017 Jan 2. doi: 10.18632/oncotarget.14440
PMCID:
PMC5355315
AbstractArticlePDF–11M
9.
Association of RAB5 overexpression in pancreatic cancer with cancer progression and poor prognosis via E-cadherin suppression
Takamichi Igarashi, Kenichiro Araki, Takehiko Yokobori, Bolag Altan, Takahiro Yamanaka, Norihiro Ishii, Mariko Tsukagoshi, Akira Watanabe, Norio Kubo, Tadashi Handa, Yasuo Hosouchi, Masahiko Nishiyama, Tetsunari Oyama, Ken Shirabe, Hiroyuki Kuwano
Oncotarget. 2017 Feb 14; 8(7): 12290–12300. Published online 2017 Jan 17. doi: 10.18632/oncotarget.14703
PMCID:
PMC5355344
AbstractArticlePDF–2.7M
10.
Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine
Costantine Albany, Mary P. Hever-Jardine, Katherine M. von Herrmann, Christina Y. Yim, Janice Tam, Joshua M. Warzecha, Leah Shin, Sarah E. Bock, Brian S. Curran, Aneeq S. Chaudhry, Fred Kim, George E. Sandusky, Pietro Taverna, Sarah J. Freemantle, Brock C. Christensen, Lawrence H. Einhorn, Michael J. Spinella
Oncotarget. 2017 Jan 10; 8(2): 2949–2959. Published online 2016 Dec 7. doi: 10.18632/oncotarget.13811
PMCID:
PMC5356854
AbstractArticlePDF–2.7M
11.
Increased expression of programmed death ligand 1 (PD-L1) in human pituitary tumors
Yu Mei, Wenya Linda Bi, Noah F. Greenwald, Ziming Du, Nathalie Y. R. Agar, Ursula B. Kaiser, Whitney W. Woodmansee, David A. Reardon, Gordon J. Freeman, Peter E. Fecci, Edward R. Laws, Jr, Sandro Santagata, Gavin P. Dunn, Ian F. Dunn
Oncotarget. 2016 Nov 22; 7(47): 76565–76576. Published online 2016 Sep 17. doi: 10.18632/oncotarget.12088
PMCID:
PMC5363530
AbstractArticlePDF–4.0M
12.
HER inhibitor promotes BRAF/MEK inhibitor-induced redifferentiation in papillary thyroid cancer harboring BRAFV600E
Lingxiao Cheng, Yuchen Jin, Min Liu, Maomei Ruan, Libo Chen
Oncotarget. 2017 Mar 21; 8(12): 19843–19854. Published online 2017 Feb 28. doi: 10.18632/oncotarget.15773
PMCID:
PMC5386727
AbstractArticlePDF–5.3M
13.
Development and Characterization of a Differentiated Thyroid Cancer Cell Line Resistant to VEGFR-Targeted Kinase Inhibitors
Crescent R. Isham, Brian C. Netzel, Ayoko R. Bossou, Dragana Milosevic, Kendall W. Cradic, Stefan K. Grebe, Keith C. Bible
J Clin Endocrinol Metab. 2014 Jun; 99(6): E936–E943. Published online 2014 Mar 14. doi: 10.1210/jc.2013-2658
PMCID:
PMC5393484
AbstractArticle
14.
Bromodomain and extraterminal protein inhibitor JQ1 suppresses thyroid tumor growth in a mouse model
Xuguang Zhu, Keisuke Enomoto, Li Zhao, Yuelin J Zhu, Mark C. Willingham, Paul Meltzer, J Qi, Sheue-yann Cheng
Clin Cancer Res. Author manuscript; available in PMC 2018 Jan 15.
Published in final edited form as: Clin Cancer Res. 2017 Jan 15; 23(2): 430–440. Published online 2016 Jul 20. doi: 10.1158/1078-0432.CCR-16-0914
PMCID:
PMC5241246
AbstractArticlePDF–1.4M
15.
Physiological and Pathological Roles in Human Adrenal of the Glomeruli-Defining Matrix Protein NPNT (Nephronectin)
Ada Ee Der Teo, Sumedha Garg, Timothy Isaac Johnson, Wanfeng Zhao, Junhua Zhou, Celso Enrique Gomez-Sanchez, Mark Gurnell, Morris Jonathan Brown
Hypertension. 2017 Jun; 69(6): 1207–1216. Published online 2017 May 10. doi: 10.1161/HYPERTENSIONAHA.117.09156
PMCID:
PMC5424579
AbstractArticlePDF–889K
16.
NADPH Oxidase NOX4 Is a Critical Mediator of BRAFV600E-Induced Downregulation of the Sodium/Iodide Symporter in Papillary Thyroid Carcinomas
Naïma Azouzi, Jérémy Cailloux, Juliana M. Cazarin, Jeffrey A. Knauf, Jennifer Cracchiolo, Abir Al Ghuzlan, Dana Hartl, Michel Polak, Aurore Carré, Mohammed El Mzibri, Abdelkarim Filali-Maltouf, Abderrahmane Al Bouzidi, Martin Schlumberger, James A. Fagin, Rabii Ameziane-El-Hassani, Corinne Dupuy
Antioxid Redox Signal. 2017 May 20; 26(15): 864–877. Published online 2017 May 20. doi: 10.1089/ars.2015.6616
PMCID:
PMC5444494
AbstractArticlePDF–837K
17.
Emergent Role of the Fractalkine Axis in Dissemination of Peritoneal Metastasis from Epithelial Ovarian Carcinoma
Hilal Gurler Main, Jia Xie, Goda G. Muralidhar, Osama Elfituri, Haoliang Xu, Andre A. Kajdacsy-Balla, Maria V. Barbolina
Oncogene. Author manuscript; available in PMC 2017 Jun 12.
Published in final edited form as: Oncogene. 2017 May 25; 36(21): 3025–3036. Published online 2016 Dec 12. doi: 10.1038/onc.2016.456
PMCID:
PMC5444995
AbstractArticlePDF–3.8M
18.
Genetic and Histopathologic Intertumor Heterogeneity in Primary Aldosteronism
Kei Omata, Yuto Yamazaki, Yasuhiro Nakamura, Sharath K. Anand, Justine A. Barletta, Hironobu Sasano, William E. Rainey, Scott A. Tomlins, Anand Vaidya
J Clin Endocrinol Metab. 2017 Jun 1; 102(6): 1792–1796. Published online 2017 Mar 24. doi: 10.1210/jc.2016-4007
PMCID:
PMC5470766
AbstractArticle
19.
Development of Circulating Tumor Cell-Endocrine Therapy Index in Patients with Hormone Receptor Positive Breast Cancer
Costanza Paoletti, Maria C. Muñiz, Dafydd G. Thomas, Kent A. Griffith, Kelley M. Kidwell, Nahomi Tokudome, Martha E. Brown, Kimberly Aung, M. Craig Miller, Dorothy L. Blossom, Anne F.Schott, Norah L. Henry, James M. Rae, Mark C. Connelly, David A. Chianese, Daniel F. Hayes
Clin Cancer Res. Author manuscript; available in PMC 2017 Jul 19.
Published in final edited form as: Clin Cancer Res. 2015 Jun 1; 21(11): 2487–2498. Published online 2014 Nov 7. doi: 10.1158/1078-0432.CCR-14-1913
PMCID:
PMC5516625
AbstractArticlePDF–866K
20.
Vemurafenib in patients with BRAFV600E-positive metastatic or unresectable papillary thyroid cancer refractory to radioactive iodine: a non-randomised, multicentre, open-label, phase 2 trial
Marcia S Brose, Maria E Cabanillas, Ezra E W Cohen, Lori J Wirth, Todd Riehl, Huibin Yue, Prof Steven I Sherman, Eric J Sherman
Lancet Oncol. Author manuscript; available in PMC 2017 Jul 28.
Published in final edited form as: Lancet Oncol. 2016 Sep; 17(9): 1272–1282. Published online 2016 Jul 23. doi: 10.1016/S1470-2045(16)30166-8
PMCID:
PMC5532535
AbstractArticlePDF–636K

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