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Select item 53539501.

Objective response to mTOR inhibition in a metastatic collision tumor of the liver composed of melanoma and adenocarcinoma with TSC1 loss: a case report

Munveer S. Bhangoo, Jenny Y. Zhou, Siraj M. Ali, Russell Madison, Alexa B. Schrock, Carrie Costantini

BMC Cancer. 2017; 17: 197. Published online 2017 Mar 16. doi: 10.1186/s12885-017-3167-y

PMCID:: PMC5353950

Abstract Article PDF–1.5M

Select item 55780532.

Appearance of New Cutaneous Superficial Basal Cell Carcinomas during Successful Nivolumab Treatment of Refractory Metastatic Disease: Implications for Immunotherapy in Early Versus Late Disease

Philip R. Cohen, Shumei Kato, Aaron M. Goodman, Sadakatsu Ikeda, Razelle Kurzrock

Int J Mol Sci. 2017 Aug; 18(8): 1663. Published online 2017 Jul 31. doi: 10.3390/ijms18081663

PMCID:: PMC5578053

Abstract Article PDF–1.3M

Select item 55704953.

A ‘synthetic-sickness’ screen for senescence re-engagement targets in mutant cancer backgrounds

Claire J. Cairney, Lauren S. Godwin, Alan E. Bilsland, Sharon Burns, Katrina H. Stevenson, Lynn McGarry, John Revie, Jon D. Moore, Ceri M. Wiggins, Rebecca S. Collinson, Clare Mudd, Elpida Tsonou, Mahito Sadaie, Dorothy C. Bennett, Masashi Narita, Christopher J. Torrance, W. Nicol Keith

PLoS Genet. 2017 Aug; 13(8): e1006942. Published online 2017 Aug 14. doi: 10.1371/journal.pgen.1006942

PMCID:: PMC5570495

Abstract Article PDF–4.8M

Select item 55570004.

Whole-blood RNA transcript-based models can predict clinical response in two large independent clinical studies of patients with advanced melanoma treated with the checkpoint inhibitor, tremelimumab

Philip Friedlander, Karl Wassmann, Alan M. Christenfeld, David Fisher, Chrisann Kyi, John M. Kirkwood, Nina Bhardwaj, William K. Oh

J Immunother Cancer. 2017; 5: 67. Published online 2017 Aug 15. doi: 10.1186/s40425-017-0272-z

PMCID:: PMC5557000

Abstract Article PDF–1.1M

Select item 55524145.

Abl Kinase Regulation by BRAF/ERK and Cooperation with Akt in Melanoma

Aditi Jain, Rakshamani Tripathi, Courtney P. Turpin, Chi Wang, Rina Plattner

Oncogene. Author manuscript; available in PMC 2017 Oct 3.

Published in final edited form as: Oncogene. 2017 Aug 10; 36(32): 4585–4596. Published online 2017 Apr 3. doi: 10.1038/onc.2017.76

PMCID:: PMC5552414

Abstract Article PDF–2.4M

Select item 55325356.

Vemurafenib in patients with BRAF^V600E-positive metastatic or unresectable papillary thyroid cancer refractory to radioactive iodine: a non-randomised, multicentre, open-label, phase 2 trial

Marcia S Brose, Maria E Cabanillas, Ezra E W Cohen, Lori J Wirth, Todd Riehl, Huibin Yue, Prof Steven I Sherman, Eric J Sherman

Lancet Oncol. Author manuscript; available in PMC 2017 Jul 28.

Published in final edited form as: Lancet Oncol. 2016 Sep; 17(9): 1272–1282. Published online 2016 Jul 23. doi: 10.1016/S1470-2045(16)30166-8

PMCID:: PMC5532535

Abstract Article PDF–636K

Select item 54900837.

Treatment of metastatic uveal melanoma with adoptive transfer of tumor infiltrating lymphocytes: a single-center phase 2 study

Smita S. Chandran, Robert P.T. Somerville, James C. Yang, Richard M. Sherry, Christopher A. Klebanoff, Stephanie L. Goff, John R. Wunderlich, David N. Danforth, Daniel Zlott, Biman C. Paria, Arvind C. Sabesan, Abhishek K. Srivastava, Liqiang Xi, Trinh H. Pham, Mark Raffeld, Donald E. White, Mary Ann Toomey, Steven A. Rosenberg, Udai S. Kammula

Lancet Oncol. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Lancet Oncol. 2017 Jun; 18(6): 792–802. Published online 2017 Apr 7. doi: 10.1016/S1470-2045(17)30251-6

PMCID:: PMC5490083

Abstract Article PDF–519K

Select item 53989228.

CD30 expression is rare in myeloid leukemia cutis; a study of 55 cases and implications for routine diagnostic algorithms

Olakunle Ogunrinade, David Terrano, April Chiu, Melissa Pulitzer

Am J Dermatopathol. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Am J Dermatopathol. 2017 May; 39(5): 351–357. doi: 10.1097/DAD.0000000000000755

PMCID:: PMC5398922

Abstract Article PDF–1.8M

Select item 53550379.

The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRAS^Q61K melanoma

Cynthia M. Simbulan-Rosenthal, Sivanesan Dakshanamurthy, Anirudh Gaur, You-Shin Chen, Hong-Bin Fang, Maryam Abdussamad, Hengbo Zhou, John Zapas, Valerie Calvert, Emanuel F. Petricoin, Michael B. Atkins, Stephen W. Byers, Dean S. Rosenthal

Oncotarget. 2017 Feb 21; 8(8): 12576–12595. Published online 2017 Feb 2. doi: 10.18632/oncotarget.14990

PMCID:: PMC5355037

Abstract Article PDF–4.3M

Select item 559658710.

Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells

Alireza Azimi, Rainer Tuominen, Fernanda Costa Svedman, Stefano Caramuta, Maria Pernemalm, Marianne Frostvik Stolt, Lena Kanter, Pedram Kharaziha, Janne Lehtiö, Carolina Hertzman Johansson, Veronica Höiom, Johan Hansson, Suzanne Egyhazi Brage

Cell Death Dis. 2017 Aug; 8(8): e3029. Published online 2017 Aug 31. doi: 10.1038/cddis.2017.406

PMCID:: PMC5596587

Abstract Article PDF–1.7M

Select item 532157711.

SF3B1 mutations are associated with alternative splicing in uveal melanoma

Simon J. Furney, Malin Pedersen, David Gentien, Amaury G. Dumont, Audrey Rapinat, Laurence Desjardins, Samra Turajlic, Sophie Piperno-Neumann, Pierre de la Grange, Sergio Roman-Roman, Marc-Henri Stern, Richard Marais

Cancer Discov. Author manuscript; available in PMC 2017 Feb 22.

Published in final edited form as: Cancer Discov. 2013 Oct; 3(10): 1122–1129. Published online 2013 Jul 16. doi: 10.1158/2159-8290.CD-13-0330

PMCID:: PMC5321577

Abstract Article PDF–908K

Select item 529137512.

Deep-proteome mapping of WM-266-4 human metastatic melanoma cells: From oncogenic addiction to druggable targets

Eumorphia G. Konstantakou, Athanassios D. Velentzas, Athanasios K. Anagnostopoulos, Zoi I. Litou, Ourania A. Konstandi, Aikaterini F. Giannopoulou, Ema Anastasiadou, Gerassimos E. Voutsinas, George Th. Tsangaris, Dimitrios J. Stravopodis

PLoS One. 2017; 12(2): e0171512. Published online 2017 Feb 3. doi: 10.1371/journal.pone.0171512

PMCID:: PMC5291375

Abstract Article PDF–3.9M

Select item 524448413.

Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors

Patricia M. LoRusso, Charles M. Rudin, Josina C. Reddy, Raoul Tibes, Glen J. Weiss, Mitesh J. Borad, Christine L. Hann, Julie R. Brahmer, Ilsung Chang, Walter C. Darbonne, Richard A. Graham, Kenn L. Zerivitz, Jennifer A. Low, Daniel D. Von Hoff

Clin Cancer Res. Author manuscript; available in PMC 2017 Jan 19.

Published in final edited form as: Clin Cancer Res. 2011 Apr 15; 17(8): 2502–2511. Published online 2011 Feb 7. doi: 10.1158/1078-0432.CCR-10-2745

PMCID:: PMC5244484

Abstract Article PDF–405K

Select item 512589514.

Senescence-like Phenotypes in Human Nevi

Andrew Joselow, Darren Lynn, Tamara Terzian, Neil F. Box

Methods Mol Biol. Author manuscript; available in PMC 2017 Jan 1.

Published in final edited form as: Methods Mol Biol. 2017; 1534: 175–184. doi: 10.1007/978-1-4939-6670-7_17

PMCID:: PMC5125895

Abstract Article PDF–878K

Select item 505365715.

Chronic arsenic trioxide exposure leads to enhanced aggressiveness via Met oncogene addiction in cancer cells

Kushtrim Kryeziu, Christine Pirker, Bernhard Englinger, Sushilla van Schoonhoven, Melanie Spitzwieser, Thomas Mohr, Wilfried Körner, Regina Weinmüllner, Koray Tav, Johannes Grillari, Margit Cichna-Markl, Walter Berger, Petra Heffeter

Oncotarget. 2016 May 10; 7(19): 27379–27393. Published online 2016 Mar 28. doi: 10.18632/oncotarget.8415

PMCID:: PMC5053657

Abstract Article PDF–10M

Select item 501382716.

Phase II Study of Nilotinib in Melanoma Harboring KIT Alterations Following Progression to Prior KIT Inhibition

Richard D. Carvajal, Donald P. Lawrence, Jeffrey S. Weber, Thomas F. Gajewski, Rene Gonzalez, Jose Lutzky, Steven J. O’Day, Omid Hamid, Jedd D. Wolchok, Paul B. Chapman, Ryan J. Sullivan, Jerrold B. Teitcher, Nikhil Ramaiya, Anita Giobbie-Hurder, Cristina R. Antonescu, Michael C. Heinrich, Boris C. Bastian, Christopher L. Corless, Jonathan A. Fletcher, F. Stephen Hodi

Clin Cancer Res. Author manuscript; available in PMC 2016 Sep 7.

Published in final edited form as: Clin Cancer Res. 2015 May 15; 21(10): 2289–2296. Published online 2015 Feb 18. doi: 10.1158/1078-0432.CCR-14-1630

PMCID:: PMC5013827

Abstract Article PDF–1.1M

Select item 498277417.

Clinical, molecular and immune analysis of dabrafenib and trametinib in metastatic melanoma patients that progressed on BRAF inhibitor monotherapy: a phase II clinical trial: CombiDT in BRAF inhibitor refractory melanoma patients

Guo Chen, Jennifer L. McQuade, David J. Panka, Courtney W. Hudgens, Ali Amin-Mansour, Xinmeng Jasmine Mu, Samira Bahl, Judit Jane-Valbuena, Khalida M. Wani, Alexandre Reuben, Caitlyn A. Creasy, Hong Jiang, Zachary A. Cooper, Jason Roszik, Roland L. Bassett, Jr., Aron Y. Joon, Lauren M. Simpson, Rosalind D. Mouton, Isabella C. Glitza, Sapna P. Patel, Wen-Jen Hwu, Rodabe N. Amaria, Adi Diab, Patrick Hwu, Alexander J. Lazar, Jennifer A. Wargo, Levi A. Garraway, Michael T. Tetzlaff, Ryan J. Sullivan, Kevin B. Kim, Michael A. Davies

JAMA Oncol. Author manuscript; available in PMC 2016 Nov 1.

Published in final edited form as: JAMA Oncol. 2016 Aug 1; 2(8): 1056–1064. doi: 10.1001/jamaoncol.2016.0509

PMCID:: PMC4982774

Abstract Article PDF–507K

Select item 497076518.

PD-1 Antibody Monotherapy for Malignant Melanoma: A Systematic Review and Meta-Analysis

Zhijuan Lin, Xing Chen, Zhifeng Li, Yiming Luo, Zhihong Fang, Bing Xu, Mingzhe Han

PLoS One. 2016; 11(8): e0160485. Published online 2016 Aug 2. doi: 10.1371/journal.pone.0160485

PMCID:: PMC4970765

Abstract Article PDF–1.9M

Select item 583386119.

Cell death-based treatments of melanoma:conventional treatments and new therapeutic strategies

Gianfranco Mattia, Rossella Puglisi, Barbara Ascione, Walter Malorni, Alessandra Carè, Paola Matarrese

Cell Death Dis. 2018 Feb; 9(2): 112. Published online 2018 Jan 25. doi: 10.1038/s41419-017-0059-7

PMCID:: PMC5833861

Abstract Article PDF–1.1M

Select item 584000720.

DKK2 imparts tumor immunity evasion through ß-catenin-independent suppression of cytotoxic immune cell activation

Qian Xiao, Jibo Wu, Wei-Jia Wang, Shiyang Chen, Yingxia Zheng, Xiaoqing Yu, Katrina Meeth, Mahnaz Sahraei, Alfred L. M. Bothwell, Lieping Chen, Marcus Bosenberg, Jianfeng Chen, Veronika Sexl, Le Sun, Lin Li, Wenwen Tang, Dianqing Wu

Nat Med. Author manuscript; available in PMC 2018 Aug 12.

Published in final edited form as: Nat Med. 2018 Mar; 24(3): 262–270. Published online 2018 Feb 12. doi: 10.1038/nm.4496

PMCID:: PMC5840007

Abstract Article PDF–3.2M

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PMC Articles for MedGen (Select 1652320) (139)
PMC
zinc finger protein neuro-d4 isoform c [Homo sapiens]
zinc finger protein neuro-d4 isoform c [Homo sapiens]
gi|205830434|ref|NP_001128628.1|

Protein
Human Flt3 ligand gene and Flt3 ligand alternatively spliced isoform gene, compl...
Human Flt3 ligand gene and Flt3 ligand alternatively spliced isoform gene, complete cds
gi|1072036|gb|U29874.1|HSU29874

Nucleotide
BORCS5 BLOC-1 related complex subunit 5 [Homo sapiens]
BORCS5 BLOC-1 related complex subunit 5 [Homo sapiens]
Gene ID:118426

Gene
Gene Links for OMIM (Select 616598) (1)
Gene

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